FR2332015A1 - Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques - Google Patents

Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques

Info

Publication number
FR2332015A1
FR2332015A1 FR7634885A FR7634885A FR2332015A1 FR 2332015 A1 FR2332015 A1 FR 2332015A1 FR 7634885 A FR7634885 A FR 7634885A FR 7634885 A FR7634885 A FR 7634885A FR 2332015 A1 FR2332015 A1 FR 2332015A1
Authority
FR
France
Prior art keywords
thienamycin
antibiotics
useful
carboxyl derivatives
carboxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634885A
Other languages
English (en)
Other versions
FR2332015B1 (fr
Inventor
B G Christensen
J Hannah
W J Leanzo
R W Ratcliffe
D H M Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2332015A1 publication Critical patent/FR2332015A1/fr
Application granted granted Critical
Publication of FR2332015B1 publication Critical patent/FR2332015B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
FR7634885A 1975-11-21 1976-11-19 Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques Granted FR2332015A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429475A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
FR2332015A1 true FR2332015A1 (fr) 1977-06-17
FR2332015B1 FR2332015B1 (fr) 1978-11-10

Family

ID=24543209

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634885A Granted FR2332015A1 (fr) 1975-11-21 1976-11-19 Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques

Country Status (8)

Country Link
JP (1) JPS5277082A (fr)
CH (1) CH633554A5 (fr)
DE (1) DE2652680A1 (fr)
DK (1) DK523376A (fr)
FR (1) FR2332015A1 (fr)
GB (1) GB1570987A (fr)
NL (1) NL7612942A (fr)
SE (1) SE7612961L (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362142A1 (fr) * 1976-08-17 1978-03-17 Beecham Group Ltd Composes antibacteriens a cycle beta-lactame
FR2371448A1 (fr) * 1976-11-17 1978-06-16 Merck & Co Inc Nouveaux b-lactames antibiotiques
EP0005348A1 (fr) * 1978-05-06 1979-11-14 Beecham Group Plc Dérivés de carbapénème, procédé pour leur préparation et compositions pharmaceutiques les contenant

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007152A1 (fr) * 1978-04-28 1980-01-23 Beecham Group Plc Antibiotiques bêta-lactames, préparation et application
DE2966187D1 (en) * 1978-08-23 1983-10-27 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
EP0044142A1 (fr) * 1980-07-03 1982-01-20 Beecham Group Plc Procédé de préparation d'antibiotiques bêta-lactame

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362142A1 (fr) * 1976-08-17 1978-03-17 Beecham Group Ltd Composes antibacteriens a cycle beta-lactame
FR2371448A1 (fr) * 1976-11-17 1978-06-16 Merck & Co Inc Nouveaux b-lactames antibiotiques
EP0005348A1 (fr) * 1978-05-06 1979-11-14 Beecham Group Plc Dérivés de carbapénème, procédé pour leur préparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
JPS5277082A (en) 1977-06-29
CH633554A5 (en) 1982-12-15
GB1570987A (en) 1980-07-09
DK523376A (da) 1977-05-22
NL7612942A (nl) 1977-05-24
JPS61345B2 (fr) 1986-01-08
SE7612961L (sv) 1977-05-22
FR2332015B1 (fr) 1978-11-10
DE2652680A1 (de) 1977-06-02

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Legal Events

Date Code Title Description
ST Notification of lapse