GB1581315A - Polysaccharides and process for the preparation thereof - Google Patents
Polysaccharides and process for the preparation thereof Download PDFInfo
- Publication number
- GB1581315A GB1581315A GB3251/78A GB325178A GB1581315A GB 1581315 A GB1581315 A GB 1581315A GB 3251/78 A GB3251/78 A GB 3251/78A GB 325178 A GB325178 A GB 325178A GB 1581315 A GB1581315 A GB 1581315A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substance
- solution
- coriolus
- ppm
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 32
- 150000004676 glycans Chemical class 0.000 title claims description 25
- 229920001282 polysaccharide Polymers 0.000 title claims description 25
- 239000005017 polysaccharide Substances 0.000 title claims description 25
- 238000002360 preparation method Methods 0.000 title description 9
- 239000000126 substance Substances 0.000 claims description 96
- 239000000243 solution Substances 0.000 claims description 44
- 238000000605 extraction Methods 0.000 claims description 39
- 150000001720 carbohydrates Chemical class 0.000 claims description 34
- 238000006243 chemical reaction Methods 0.000 claims description 28
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 27
- 241000222356 Coriolus Species 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 22
- 238000010521 absorption reaction Methods 0.000 claims description 19
- 238000000862 absorption spectrum Methods 0.000 claims description 16
- 239000000284 extract Substances 0.000 claims description 16
- 239000003513 alkali Substances 0.000 claims description 15
- 241000233866 Fungi Species 0.000 claims description 14
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 10
- 239000002244 precipitate Substances 0.000 claims description 10
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- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 9
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- 230000002622 anti-tumorigenesis Effects 0.000 claims description 9
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- 235000011121 sodium hydroxide Nutrition 0.000 claims description 9
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 8
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 8
- 241000222357 Trametes hirsuta Species 0.000 claims description 8
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 8
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims description 8
- 235000011130 ammonium sulphate Nutrition 0.000 claims description 8
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- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
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- HHIVCXLCMPHUSC-UHFFFAOYSA-N hydron;1h-indol-1-ium;sulfate Chemical compound OS(O)(=O)=O.C1=CC=C2NC=CC2=C1 HHIVCXLCMPHUSC-UHFFFAOYSA-N 0.000 claims description 3
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- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 claims description 3
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- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 4
- GUBGYTABKSRVRQ-WFVLMXAXSA-N DEAE-cellulose Chemical compound OC1C(O)C(O)C(CO)O[C@H]1O[C@@H]1C(CO)OC(O)C(O)C1O GUBGYTABKSRVRQ-WFVLMXAXSA-N 0.000 description 4
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- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
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- 150000008163 sugars Chemical class 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 239000005051 trimethylchlorosilane Substances 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP727277A JPS5394012A (en) | 1977-01-27 | 1977-01-27 | Novel polysaccharide and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1581315A true GB1581315A (en) | 1980-12-10 |
Family
ID=11661383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3251/78A Expired GB1581315A (en) | 1977-01-27 | 1978-01-26 | Polysaccharides and process for the preparation thereof |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5394012A (fr) |
| AU (1) | AU501257B1 (fr) |
| CA (1) | CA1086720A (fr) |
| DE (1) | DE2803681A1 (fr) |
| FR (1) | FR2378799A1 (fr) |
| GB (1) | GB1581315A (fr) |
| IT (1) | IT1112608B (fr) |
| SU (1) | SU1403990A3 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5461112A (en) * | 1977-10-24 | 1979-05-17 | Ono Pharmaceut Co Ltd | Oncostatic polysaccharide* its preparation* and oncostatic drugs containing it as an effective component |
| JPS5712999A (en) * | 1980-06-25 | 1982-01-22 | Chiyokichi Iizuka | Antibiral agent and its preparation |
| DE3172841D1 (en) * | 1980-09-29 | 1985-12-12 | Shell Int Research | Treatment of pseudoplastic polysaccharide solutions |
| JPH0312628Y2 (fr) * | 1986-12-15 | 1991-03-25 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757248A (fr) * | 1969-10-15 | 1971-04-08 | Kureha Chemical Ind Co Ltd | Substance a propriete anticancereuse et procedes pour sa preparation |
| JPS536412A (en) * | 1976-07-07 | 1978-01-20 | Kureha Chem Ind Co Ltd | Preparation of n-containing polysaccharides |
| JPS536413A (en) * | 1976-07-07 | 1978-01-20 | Kureha Chem Ind Co Ltd | Preparation of n-containing polysaccharides |
| JPS5315495A (en) * | 1976-07-22 | 1978-02-13 | Kureha Chem Ind Co Ltd | Preparation of polysaccharides |
-
1977
- 1977-01-27 JP JP727277A patent/JPS5394012A/ja active Granted
-
1978
- 1978-01-16 CA CA295,008A patent/CA1086720A/fr not_active Expired
- 1978-01-18 AU AU32521/78A patent/AU501257B1/en not_active Expired
- 1978-01-26 GB GB3251/78A patent/GB1581315A/en not_active Expired
- 1978-01-26 SU SU782574401A patent/SU1403990A3/ru active
- 1978-01-27 DE DE19782803681 patent/DE2803681A1/de active Granted
- 1978-01-27 FR FR7802325A patent/FR2378799A1/fr active Granted
- 1978-01-27 IT IT19741/78A patent/IT1112608B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| IT7819741A0 (it) | 1978-01-27 |
| FR2378799A1 (fr) | 1978-08-25 |
| DE2803681A1 (de) | 1978-08-17 |
| FR2378799B1 (fr) | 1980-09-05 |
| JPS5394012A (en) | 1978-08-17 |
| SU1403990A3 (ru) | 1988-06-15 |
| IT1112608B (it) | 1986-01-20 |
| DE2803681C2 (fr) | 1989-03-16 |
| CA1086720A (fr) | 1980-09-30 |
| JPS5646481B2 (fr) | 1981-11-04 |
| AU501257B1 (en) | 1979-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19970126 |