GB1580715A - Refining process for crude saccharin-sodium - Google Patents
Refining process for crude saccharin-sodium Download PDFInfo
- Publication number
- GB1580715A GB1580715A GB32121/77A GB3212177A GB1580715A GB 1580715 A GB1580715 A GB 1580715A GB 32121/77 A GB32121/77 A GB 32121/77A GB 3212177 A GB3212177 A GB 3212177A GB 1580715 A GB1580715 A GB 1580715A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sodium
- saccharin
- crude
- methylene chloride
- crude solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 title claims description 40
- 229940085605 saccharin sodium Drugs 0.000 title claims description 40
- 238000000034 method Methods 0.000 title claims description 29
- 238000007670 refining Methods 0.000 title claims description 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims description 93
- 239000012045 crude solution Substances 0.000 claims description 36
- 238000000605 extraction Methods 0.000 claims description 33
- 239000012535 impurity Substances 0.000 claims description 12
- 238000004821 distillation Methods 0.000 claims description 9
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 238000003786 synthesis reaction Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 239000013078 crystal Substances 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 238000003860 storage Methods 0.000 description 15
- 230000010349 pulsation Effects 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000002425 crystallisation Methods 0.000 description 5
- 239000011521 glass Substances 0.000 description 5
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- YCMLQMDWSXFTIF-UHFFFAOYSA-N 2-methylbenzenesulfonimidic acid Chemical compound CC1=CC=CC=C1S(N)(=O)=O YCMLQMDWSXFTIF-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000010413 mother solution Substances 0.000 description 3
- 229910000027 potassium carbonate Inorganic materials 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 230000001804 emulsifying effect Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 238000013019 agitation Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
- Seasonings (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU75518A LU75518A1 (enExample) | 1976-08-02 | 1976-08-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1580715A true GB1580715A (en) | 1980-12-03 |
Family
ID=19728315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32121/77A Expired GB1580715A (en) | 1976-08-02 | 1977-08-01 | Refining process for crude saccharin-sodium |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4158006A (enExample) |
| JP (1) | JPS5318774A (enExample) |
| DD (1) | DD130579A5 (enExample) |
| DE (1) | DE2730861A1 (enExample) |
| ES (1) | ES461163A1 (enExample) |
| FR (1) | FR2360586A1 (enExample) |
| GB (1) | GB1580715A (enExample) |
| IN (1) | IN146418B (enExample) |
| IT (1) | IT1079385B (enExample) |
| LU (1) | LU75518A1 (enExample) |
| SE (1) | SE7708777L (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103508974B (zh) * | 2012-06-28 | 2016-02-17 | 张卫民 | 一种处理邻磺酰胺苯甲酸甲酯结晶母液的方法 |
| CN110776476B (zh) * | 2019-12-02 | 2021-06-08 | 北京海泰天正医药科技有限公司 | 药用级邻苯甲酰磺酰亚胺盐及其制备方法 |
| CN115745908A (zh) * | 2022-11-16 | 2023-03-07 | 河南莱伯瑞特科技有限公司 | 1,1-二氧代-1,2-苯并异噻唑-3(2h)-酮钠盐结晶工艺 |
| CN116589429A (zh) * | 2023-05-22 | 2023-08-15 | 江西富味特生物技术有限公司 | 一种颗粒状糖精钠的制备方法及其制备系统 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3988344A (en) * | 1975-06-10 | 1976-10-26 | Daiwa Kasei Kabushiki Kaisha | Process for purifying saccharin |
-
1976
- 1976-08-02 LU LU75518A patent/LU75518A1/xx unknown
-
1977
- 1977-07-08 DE DE19772730861 patent/DE2730861A1/de not_active Withdrawn
- 1977-07-15 IN IN1092/CAL/77A patent/IN146418B/en unknown
- 1977-07-25 JP JP8847577A patent/JPS5318774A/ja active Pending
- 1977-07-27 US US05/819,255 patent/US4158006A/en not_active Expired - Lifetime
- 1977-07-27 IT IT50455/77A patent/IT1079385B/it active
- 1977-07-28 DD DD7700200328A patent/DD130579A5/xx unknown
- 1977-07-29 ES ES461163A patent/ES461163A1/es not_active Expired
- 1977-07-29 FR FR7723474A patent/FR2360586A1/fr active Granted
- 1977-08-01 SE SE7708777A patent/SE7708777L/xx not_active Application Discontinuation
- 1977-08-01 GB GB32121/77A patent/GB1580715A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4158006A (en) | 1979-06-12 |
| JPS5318774A (en) | 1978-02-21 |
| LU75518A1 (enExample) | 1978-02-13 |
| ES461163A1 (es) | 1978-12-01 |
| IN146418B (enExample) | 1979-05-26 |
| SE7708777L (sv) | 1978-02-03 |
| DD130579A5 (de) | 1978-04-12 |
| FR2360586A1 (fr) | 1978-03-03 |
| IT1079385B (it) | 1985-05-08 |
| DE2730861A1 (de) | 1978-02-09 |
| FR2360586B1 (enExample) | 1980-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US2330221A (en) | Method and apparatus for concentrating liquids which upon concentration deposit crystals and leave a residual concentrated liquor | |
| NO319309B1 (no) | Fremgangsmate for fremstilling av en vandig losning av fritt hydroksylamin | |
| US20040030124A1 (en) | Process for recovering chlorosucrose compounds | |
| US2827366A (en) | Crystallization apparatus | |
| GB1580715A (en) | Refining process for crude saccharin-sodium | |
| KR900006420B1 (ko) | 분사식 결정화방법 및 장치 | |
| JPS59209607A (ja) | 物質混合物の結晶化分離装置 | |
| CN104903236B (zh) | 生产硫酸铵晶体的方法和装置 | |
| JP4183286B2 (ja) | 高純度ヒドロキシルアミン水溶液の製造 | |
| CN115228121B (zh) | 串联式精馏回收装置及其方法和应用 | |
| KR101099150B1 (ko) | 아디프산의 질산 수용액으로부터의 아디프산의 결정화 | |
| JPH06114259A (ja) | 多目的化学品製造設備の構成と操作方法 | |
| Chen et al. | Crystallization kinetics of calcium nitrate tetrahydrate from MSMPR crystallizer | |
| WO2020161226A1 (en) | A process for obtaining 4,4'-dichlorodiphenyl sulfoxide | |
| US3335083A (en) | Solid-liquid sea water heater with scale removing features | |
| WO2020161228A1 (en) | Process for producing 4,4`-dichlorodiphenyl sulfoxide | |
| KR820001173B1 (ko) | 조삭카린-나트륨의 정제방법 | |
| US5466266A (en) | Closed system multistage superpurification recrystallization | |
| JPH10156103A (ja) | 晶析方法及び晶析装置 | |
| CN211585289U (zh) | 一种连续恒浓度结晶装置 | |
| US984645A (en) | Process for producing large well-formed crystals from solutions of different kinds. | |
| RU2834723C1 (ru) | Установка для нитрозирования фенола | |
| DE102004054433A1 (de) | Verfahren zur Wiedergewinnung von Calciumchlorid aus Abwässern der Epichlorhydrinproduktion | |
| GB2128496A (en) | Multi-stage recrystallization and crystallizer | |
| US2467274A (en) | Process and apparatus for recovering in the form of alkali metal salts the oxides of nitrogen from gases containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |