GB1577232A - Peptide derivatives of phosphonic and phosphinic acids - Google Patents

Peptide derivatives of phosphonic and phosphinic acids Download PDF

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Publication number
GB1577232A
GB1577232A GB20014/76A GB2001476A GB1577232A GB 1577232 A GB1577232 A GB 1577232A GB 20014/76 A GB20014/76 A GB 20014/76A GB 2001476 A GB2001476 A GB 2001476A GB 1577232 A GB1577232 A GB 1577232A
Authority
GB
United Kingdom
Prior art keywords
alanyl
alanylamino
group
acid
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20014/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Priority to GB20014/76A priority Critical patent/GB1577232A/en
Priority to NL7704370A priority patent/NL7704370A/xx
Priority to IT23054/77A priority patent/IT1075484B/it
Priority to IL52040A priority patent/IL52040A/xx
Priority to ZA00772732A priority patent/ZA772732B/xx
Priority to AU25008/77A priority patent/AU511452B2/en
Priority to NZ184047A priority patent/NZ184047A/xx
Priority to PH19754A priority patent/PH14715A/en
Priority to FI771518A priority patent/FI771518A7/fi
Priority to LU77319A priority patent/LU77319A1/xx
Priority to FR7714549A priority patent/FR2351124A1/fr
Priority to CA278,276A priority patent/CA1090785A/en
Priority to AT345877A priority patent/AT355740B/de
Priority to NO771717A priority patent/NO771717L/no
Priority to JP5447577A priority patent/JPS52139023A/ja
Priority to ES458748A priority patent/ES458748A1/es
Priority to SE7705628A priority patent/SE7705628L/xx
Priority to PT66544A priority patent/PT66544B/pt
Priority to GR53459A priority patent/GR73010B/el
Priority to DE19772721760 priority patent/DE2721760A1/de
Priority to BE177536A priority patent/BE854591A/xx
Priority to DK209877A priority patent/DK209877A/da
Priority to MC771242A priority patent/MC1146A1/fr
Publication of GB1577232A publication Critical patent/GB1577232A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB20014/76A 1976-05-14 1976-05-14 Peptide derivatives of phosphonic and phosphinic acids Expired GB1577232A (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GB20014/76A GB1577232A (en) 1976-05-14 1976-05-14 Peptide derivatives of phosphonic and phosphinic acids
NL7704370A NL7704370A (nl) 1976-05-14 1977-04-21 Werkwijze voor het bereiden van peptidederivaten.
IT23054/77A IT1075484B (it) 1976-05-14 1977-04-29 Derivati di peptidi e procedimento per la loro preparazione
IL52040A IL52040A (en) 1976-05-14 1977-05-06 Peptidyl derivatives of phosphonic acids,their manufacture and pharmaceutical compositions containing them
ZA00772732A ZA772732B (en) 1976-05-14 1977-05-06 Peptide derivatives and process for the preparation thereof
AU25008/77A AU511452B2 (en) 1976-05-14 1977-05-09 Peptide derivatives
NZ184047A NZ184047A (en) 1976-05-14 1977-05-09 Peptide derivatives of phosohonic and phosphinic acides and pharmaceutical compositions
PH19754A PH14715A (en) 1976-05-14 1977-05-10 Peptide derivatives and compositions containing same
FI771518A FI771518A7 (enExample) 1976-05-14 1977-05-12
LU77319A LU77319A1 (enExample) 1976-05-14 1977-05-12
FR7714549A FR2351124A1 (fr) 1976-05-14 1977-05-12 Derives peptidiques et procede pour leur preparation
CA278,276A CA1090785A (en) 1976-05-14 1977-05-12 Peptide derivatives and process for the preparation thereof
AT345877A AT355740B (de) 1976-05-14 1977-05-13 Verfahren zur herstellung von neuen peptid- derivaten
NO771717A NO771717L (no) 1976-05-14 1977-05-13 Peptid-derivater og fremgangsm}te for fremstilling av disse
JP5447577A JPS52139023A (en) 1976-05-14 1977-05-13 Peptide derivative
ES458748A ES458748A1 (es) 1976-05-14 1977-05-13 Un procedimiento para la preparacion de derivados peptidi- cos.
SE7705628A SE7705628L (sv) 1976-05-14 1977-05-13 Peptidderivat och forfarande for framstellning derav
PT66544A PT66544B (en) 1976-05-14 1977-05-13 Process for preparing peptide derivatives
GR53459A GR73010B (enExample) 1976-05-14 1977-05-13
DE19772721760 DE2721760A1 (de) 1976-05-14 1977-05-13 Peptidderivate und verfahren zu deren herstellung
BE177536A BE854591A (fr) 1976-05-14 1977-05-13 Derives peptidiques et procede pour leur preparation
DK209877A DK209877A (da) 1976-05-14 1977-05-13 Fremgangsmade til fremstilling af peptidderivater
MC771242A MC1146A1 (fr) 1976-05-14 1977-05-13 Derives peptidiques et procede pour leur preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB20014/76A GB1577232A (en) 1976-05-14 1976-05-14 Peptide derivatives of phosphonic and phosphinic acids

Publications (1)

Publication Number Publication Date
GB1577232A true GB1577232A (en) 1980-10-22

Family

ID=10138919

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20014/76A Expired GB1577232A (en) 1976-05-14 1976-05-14 Peptide derivatives of phosphonic and phosphinic acids

Country Status (23)

Country Link
JP (1) JPS52139023A (enExample)
AT (1) AT355740B (enExample)
AU (1) AU511452B2 (enExample)
BE (1) BE854591A (enExample)
CA (1) CA1090785A (enExample)
DE (1) DE2721760A1 (enExample)
DK (1) DK209877A (enExample)
ES (1) ES458748A1 (enExample)
FI (1) FI771518A7 (enExample)
FR (1) FR2351124A1 (enExample)
GB (1) GB1577232A (enExample)
GR (1) GR73010B (enExample)
IL (1) IL52040A (enExample)
IT (1) IT1075484B (enExample)
LU (1) LU77319A1 (enExample)
MC (1) MC1146A1 (enExample)
NL (1) NL7704370A (enExample)
NO (1) NO771717L (enExample)
NZ (1) NZ184047A (enExample)
PH (1) PH14715A (enExample)
PT (1) PT66544B (enExample)
SE (1) SE7705628L (enExample)
ZA (1) ZA772732B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0103867A1 (en) * 1982-09-17 1984-03-28 Kyowa Hakko Kogyo Co., Ltd. Phosphorus-containing peptide derivative

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002039A1 (en) * 1977-11-19 1979-05-30 Ciba-Geigy Ag Phosphonous acid derivatives, processes for their preparation and their use in combating microorganisms
EP0010067B1 (en) * 1978-10-05 1983-08-31 Ciba-Geigy Ag Process for influencing plant growth

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51639B1 (enExample) * 1971-07-28 1976-01-09
IL48835A (en) * 1975-01-27 1979-05-31 Sparamedica Ag Amino acyl and peptidyl derivatives of phophonic acids, their preparation and pharmaceutical compositions containingthem

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0103867A1 (en) * 1982-09-17 1984-03-28 Kyowa Hakko Kogyo Co., Ltd. Phosphorus-containing peptide derivative
US4677125A (en) * 1982-09-17 1987-06-30 Kyowa Hakko Kogyo Co., Ltd. Phosphorus-containing peptide derivatives

Also Published As

Publication number Publication date
LU77319A1 (enExample) 1978-06-26
CA1090785A (en) 1980-12-02
BE854591A (fr) 1977-11-14
DK209877A (da) 1977-11-15
FI771518A7 (enExample) 1977-11-15
AU511452B2 (en) 1980-08-21
ES458748A1 (es) 1978-03-01
IT1075484B (it) 1985-04-22
NZ184047A (en) 1980-04-28
FR2351124B1 (enExample) 1981-02-13
PH14715A (en) 1981-11-13
PT66544A (en) 1977-06-01
ZA772732B (en) 1978-04-26
FR2351124A1 (fr) 1977-12-09
DE2721760A1 (de) 1977-12-01
NO771717L (no) 1977-11-15
SE7705628L (sv) 1977-11-15
AU2500877A (en) 1978-11-16
MC1146A1 (fr) 1978-01-30
IL52040A0 (en) 1977-07-31
PT66544B (en) 1979-04-12
JPS52139023A (en) 1977-11-19
IL52040A (en) 1979-11-30
AT355740B (de) 1980-03-25
ATA345877A (de) 1979-08-15
NL7704370A (nl) 1977-11-16
GR73010B (enExample) 1984-01-24

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee