GB1574182A - 7-acylamino 3-carbamoyloxymethylcephalosporin antibiotics - Google Patents

7-acylamino 3-carbamoyloxymethylcephalosporin antibiotics Download PDF

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Publication number
GB1574182A
GB1574182A GB6166/77A GB616677A GB1574182A GB 1574182 A GB1574182 A GB 1574182A GB 6166/77 A GB6166/77 A GB 6166/77A GB 616677 A GB616677 A GB 616677A GB 1574182 A GB1574182 A GB 1574182A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
hydrogen
phenyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6166/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB1574182A publication Critical patent/GB1574182A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB6166/77A 1976-02-20 1977-02-15 7-acylamino 3-carbamoyloxymethylcephalosporin antibiotics Expired GB1574182A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/660,197 US4061630A (en) 1976-02-20 1976-02-20 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
GB1574182A true GB1574182A (en) 1980-09-03

Family

ID=24648544

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6166/77A Expired GB1574182A (en) 1976-02-20 1977-02-15 7-acylamino 3-carbamoyloxymethylcephalosporin antibiotics

Country Status (18)

Country Link
US (1) US4061630A (US20030199744A1-20031023-C00003.png)
JP (1) JPS52102294A (US20030199744A1-20031023-C00003.png)
AU (1) AU509375B2 (US20030199744A1-20031023-C00003.png)
BE (1) BE851632A (US20030199744A1-20031023-C00003.png)
CA (1) CA1133895A (US20030199744A1-20031023-C00003.png)
CH (1) CH636622A5 (US20030199744A1-20031023-C00003.png)
DE (1) DE2707060A1 (US20030199744A1-20031023-C00003.png)
DK (1) DK73377A (US20030199744A1-20031023-C00003.png)
ES (2) ES456083A1 (US20030199744A1-20031023-C00003.png)
FI (1) FI770503A (US20030199744A1-20031023-C00003.png)
FR (1) FR2341583A1 (US20030199744A1-20031023-C00003.png)
GB (1) GB1574182A (US20030199744A1-20031023-C00003.png)
IE (1) IE44761B1 (US20030199744A1-20031023-C00003.png)
IL (1) IL51430A (US20030199744A1-20031023-C00003.png)
NL (1) NL7701663A (US20030199744A1-20031023-C00003.png)
NZ (1) NZ183310A (US20030199744A1-20031023-C00003.png)
SE (1) SE7701844L (US20030199744A1-20031023-C00003.png)
ZA (1) ZA77715B (US20030199744A1-20031023-C00003.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1479711A (en) * 1973-06-12 1977-07-13 Beecham Group Ltd Acylureido cephalosporins
FR2362146A1 (fr) * 1976-08-17 1978-03-17 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 7-(n-substitue-2-phenylglycinamido)-3-substitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, a activite antibacterienne
DK225179A (da) * 1978-06-22 1979-12-23 Chugai Pharmaceutical Co Ltd Fremgangsmaade til fremstilling af cephalosporinderivater
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPS58135892A (ja) * 1982-02-05 1983-08-12 Chugai Pharmaceut Co Ltd セフアロスポリン誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3706746A (en) * 1968-11-07 1972-12-19 Ciba Geigy Corp O-desacetyl derivatives of 7-n-acylamino-cephalosphoranic acids
US3687949A (en) * 1969-01-21 1972-08-29 Bristol Myers Co Synthetic cephalosporins
US3673183A (en) * 1969-11-17 1972-06-27 Squibb & Sons Inc {60 -ureidocephalosporanic acid compounds
US3741962A (en) * 1971-05-21 1973-06-26 Squibb & Sons Inc Alpha-thioureidocephalosporanic acid compounds
GB1479711A (en) * 1973-06-12 1977-07-13 Beecham Group Ltd Acylureido cephalosporins
DE2354219A1 (de) * 1973-10-30 1975-05-07 Bayer Ag Beta-lactam-antibiotica, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3956292A (en) * 1974-04-01 1976-05-11 Eli Lilly And Company 7-(α-FUROYLUREIDOARYL AND CYCLOHEXADIENYLACETAMIDO) CEPHALOSPORIN ANTIBIOTICS

Also Published As

Publication number Publication date
AU509375B2 (en) 1980-05-08
ZA77715B (en) 1978-09-27
US4061630A (en) 1977-12-06
ES468737A1 (es) 1979-01-01
IL51430A0 (en) 1977-04-29
IE44761B1 (en) 1982-03-24
AU2244177A (en) 1978-08-24
DE2707060A1 (de) 1977-08-25
NZ183310A (en) 1978-11-13
BE851632A (fr) 1977-08-18
SE7701844L (sv) 1977-08-21
FR2341583A1 (fr) 1977-09-16
JPS52102294A (en) 1977-08-27
FR2341583B1 (US20030199744A1-20031023-C00003.png) 1980-02-29
IE44761L (en) 1977-08-20
NL7701663A (nl) 1977-08-23
CH636622A5 (de) 1983-06-15
FI770503A (US20030199744A1-20031023-C00003.png) 1977-08-21
CA1133895A (en) 1982-10-19
DK73377A (da) 1977-08-21
ES456083A1 (es) 1978-10-16
IL51430A (en) 1981-07-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee