GB1570613A - Biologically active tricyclic compounds and pharmaceutical compositions containing same - Google Patents

Biologically active tricyclic compounds and pharmaceutical compositions containing same Download PDF

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Publication number
GB1570613A
GB1570613A GB44675/76A GB4467576A GB1570613A GB 1570613 A GB1570613 A GB 1570613A GB 44675/76 A GB44675/76 A GB 44675/76A GB 4467576 A GB4467576 A GB 4467576A GB 1570613 A GB1570613 A GB 1570613A
Authority
GB
United Kingdom
Prior art keywords
bicyclol
compound
alkyl
formula
benzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44675/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Priority to GB44675/76A priority Critical patent/GB1570613A/en
Priority to ZA00776142A priority patent/ZA776142B/xx
Priority to IE2103/77A priority patent/IE45889B1/en
Priority to FR7731916A priority patent/FR2369245A1/fr
Priority to AU29983/77A priority patent/AU513607B2/en
Priority to DE19772747987 priority patent/DE2747987A1/de
Priority to CA289,547A priority patent/CA1081704A/en
Priority to DK474977A priority patent/DK147280C/da
Priority to LU78392A priority patent/LU78392A1/xx
Priority to BE182088A priority patent/BE860141A/xx
Priority to HU77AO455A priority patent/HU178984B/hu
Priority to ES463570A priority patent/ES463570A1/es
Priority to FI773193A priority patent/FI64574C/fi
Priority to SE7712040A priority patent/SE425779B/xx
Priority to JP12856577A priority patent/JPS5368767A/ja
Priority to NL7711777A priority patent/NL7711777A/xx
Publication of GB1570613A publication Critical patent/GB1570613A/en
Priority to US07/098,203 priority patent/US4801753A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB44675/76A 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same Expired GB1570613A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GB44675/76A GB1570613A (en) 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same
ZA00776142A ZA776142B (en) 1976-10-27 1977-10-14 Biologically active tricyclic compounds and pharmaceutical compositions containing same
IE2103/77A IE45889B1 (en) 1976-10-27 1977-10-14 Biologically active tricyclic compounds and pharmaceutical compositions containing same
FR7731916A FR2369245A1 (fr) 1976-10-27 1977-10-24 Composes tricycliques a activite biologique et compositions pharmaceutiques les renfermant
AU29983/77A AU513607B2 (en) 1976-10-27 1977-10-24 4-amino-benzo(b)bicyclo(33)noners derivatives with anti-depressant properties
BE182088A BE860141A (fr) 1976-10-27 1977-10-26 Composes tricycliques a activite biologique et compositions pharmaceutiques les renfermant
FI773193A FI64574C (fi) 1976-10-27 1977-10-26 Foerfarande foer framstaellning av nya biologiskt aktiva 4-aminobensobicylko (3,3,1) nonenderivat
DK474977A DK147280C (da) 1976-10-27 1977-10-26 Analogifremgangsmaade til fremstilling af 4-amino-benzo(b)bicyklo(3,3,1)nonenderivater
LU78392A LU78392A1 (US07223432-20070529-C00017.png) 1976-10-27 1977-10-26
DE19772747987 DE2747987A1 (de) 1976-10-27 1977-10-26 4-amino-benzo(b)bicyclo eckige klammer auf 3,3,1 eckige klammer zu -nonen-derivate und verfahren zu ihrer herstellung und arzneimittel, enthaltend diese verbindungen
HU77AO455A HU178984B (en) 1976-10-27 1977-10-26 Process for preparing biologically active benzo/b/bicyclo/3,3,1/-nonene derivatives
ES463570A ES463570A1 (es) 1976-10-27 1977-10-26 Un procedimiento para la preparacion de nuevos compuestos triciclicos biologicamente activos
CA289,547A CA1081704A (en) 1976-10-27 1977-10-26 Biologically active tricyclic compounds and pharmaceutical compositions containing same
SE7712040A SE425779B (sv) 1976-10-27 1977-10-26 Forfarande for framst.llning av nya 4-amino-benso(b)bicyklo(3.3.1)nonenderivat
JP12856577A JPS5368767A (en) 1976-10-27 1977-10-26 Biologically active tricyclic compound process for preparing same and medical composition containing same
NL7711777A NL7711777A (nl) 1976-10-27 1977-10-27 Biologisch actieve tricyclische verbindingen en farmaceutische samenstellingen, welke deze verbindingen als actief bestanddeel bevatten.
US07/098,203 US4801753A (en) 1976-10-27 1987-09-17 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB44675/76A GB1570613A (en) 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Publications (1)

Publication Number Publication Date
GB1570613A true GB1570613A (en) 1980-07-02

Family

ID=10434306

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44675/76A Expired GB1570613A (en) 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Country Status (17)

Country Link
US (1) US4801753A (US07223432-20070529-C00017.png)
JP (1) JPS5368767A (US07223432-20070529-C00017.png)
AU (1) AU513607B2 (US07223432-20070529-C00017.png)
BE (1) BE860141A (US07223432-20070529-C00017.png)
CA (1) CA1081704A (US07223432-20070529-C00017.png)
DE (1) DE2747987A1 (US07223432-20070529-C00017.png)
DK (1) DK147280C (US07223432-20070529-C00017.png)
ES (1) ES463570A1 (US07223432-20070529-C00017.png)
FI (1) FI64574C (US07223432-20070529-C00017.png)
FR (1) FR2369245A1 (US07223432-20070529-C00017.png)
GB (1) GB1570613A (US07223432-20070529-C00017.png)
HU (1) HU178984B (US07223432-20070529-C00017.png)
IE (1) IE45889B1 (US07223432-20070529-C00017.png)
LU (1) LU78392A1 (US07223432-20070529-C00017.png)
NL (1) NL7711777A (US07223432-20070529-C00017.png)
SE (1) SE425779B (US07223432-20070529-C00017.png)
ZA (1) ZA776142B (US07223432-20070529-C00017.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0535191Y2 (US07223432-20070529-C00017.png) * 1986-06-23 1993-09-07
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
US5215992A (en) * 1990-04-30 1993-06-01 G. D. Searle & Co. Ethanobicyclic amine derivatives for CNS disorders
US5089506A (en) * 1990-04-30 1992-02-18 G. D. Searle & Co. Ethanobicyclic amine derivatives for cns disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159677A (en) * 1960-04-12 1964-12-01 Parke Davis & Co Fluorenamines and process for preparation thereof
US3836670A (en) * 1971-11-19 1974-09-17 American Home Prod Benzobicycloalkane amines for inducing analgesia
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4313896A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Aryloxyphenylpropylamines
GB1504694A (en) * 1974-04-08 1978-03-22 Akzo Nv Benzo-bicyclononene derivatives
GB1549172A (en) * 1975-04-29 1979-08-01 Akzonv Benzobicyclononene derivatives

Also Published As

Publication number Publication date
JPS5368767A (en) 1978-06-19
BE860141A (fr) 1978-04-26
HU178984B (en) 1982-07-28
NL7711777A (nl) 1978-05-02
DE2747987C2 (US07223432-20070529-C00017.png) 1988-02-25
DK474977A (da) 1978-04-28
FR2369245A1 (fr) 1978-05-26
US4801753A (en) 1989-01-31
FI64574B (fi) 1983-08-31
ZA776142B (en) 1978-06-28
LU78392A1 (US07223432-20070529-C00017.png) 1978-01-26
DK147280B (da) 1984-06-04
IE45889L (en) 1978-04-27
DK147280C (da) 1984-12-03
SE7712040L (sv) 1978-04-28
ES463570A1 (es) 1979-09-16
IE45889B1 (en) 1982-12-29
FR2369245B1 (US07223432-20070529-C00017.png) 1980-09-26
AU513607B2 (en) 1980-12-11
CA1081704A (en) 1980-07-15
FI64574C (fi) 1983-12-12
AU2998377A (en) 1979-05-03
DE2747987A1 (de) 1978-05-03
FI773193A (fi) 1978-04-28
SE425779B (sv) 1982-11-08
JPS6126773B2 (US07223432-20070529-C00017.png) 1986-06-21

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee