GB1568981A - Cyclization of peptides - Google Patents
Cyclization of peptides Download PDFInfo
- Publication number
- GB1568981A GB1568981A GB44382/76A GB4438276A GB1568981A GB 1568981 A GB1568981 A GB 1568981A GB 44382/76 A GB44382/76 A GB 44382/76A GB 4438276 A GB4438276 A GB 4438276A GB 1568981 A GB1568981 A GB 1568981A
- Authority
- GB
- United Kingdom
- Prior art keywords
- peptide
- boc
- cys
- cycle
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/15—Oxytocin or vasopressin; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/631,408 US4033940A (en) | 1975-11-12 | 1975-11-12 | Cyclization of peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1568981A true GB1568981A (en) | 1980-06-11 |
Family
ID=24531072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB44382/76A Expired GB1568981A (en) | 1975-11-12 | 1976-10-26 | Cyclization of peptides |
Country Status (5)
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4216141A (en) * | 1978-07-19 | 1980-08-05 | The Salk Institute For Biological Studies | Method for cyclization of peptides |
US4212795A (en) * | 1978-11-13 | 1980-07-15 | Armour Pharmaceutical Company | Cyclization of peptides |
SE447263B (sv) * | 1979-04-20 | 1986-11-03 | Bonnierfoeretagen Ab | Syntetisk, antigeniskt aktiv polypeptid och antigeniskt medel innehallande nemnda polypeptid |
EP0645450A1 (en) * | 1981-07-15 | 1995-03-29 | Celltech Therapeutics Limited | Human calcitonin precursor polyprotein structural gene |
US4469632A (en) * | 1982-09-24 | 1984-09-04 | Armour Pharmaceutical Company | D-Arginine24 calcitonin |
US4444681A (en) * | 1982-09-24 | 1984-04-24 | Armour Pharmaceutical Company | L-Tyrosine21 calcitonin |
US4451395A (en) * | 1982-11-08 | 1984-05-29 | Armour Pharmaceutical Company | Des-serine2 -des-tyrosine22 calcitonin |
US4663309A (en) * | 1983-06-29 | 1987-05-05 | University Patents, Inc. | Novel peptide hormones with calcitonin-like activity |
US4528132A (en) * | 1984-01-13 | 1985-07-09 | Armour Pharmaceutical Company | [16-Alanine]calcitonin |
US4623716A (en) | 1984-11-01 | 1986-11-18 | Usv Pharmaceutical Corp. | Process for the preparation and purification of peptides |
JPS61112099A (ja) * | 1984-11-06 | 1986-05-30 | Mitsubishi Petrochem Co Ltd | 新規ポリペプチド及びその製造法 |
US4604238A (en) * | 1984-12-10 | 1986-08-05 | Armour Pharmaceutical Company | Analogs of calcitonin |
US4820804A (en) * | 1987-04-21 | 1989-04-11 | Rorer Pharmaceutical Corporation | Analogs of [1,7-di-alanine, des-19-leucine]calcitonin |
US4824936A (en) * | 1987-05-06 | 1989-04-25 | Rorer Pharmaceutical Corporation | (19-Alanine) calcitonin |
JPH09502425A (ja) * | 1993-06-29 | 1997-03-11 | フエリング ビー ヴイ | デスモプレッシン鼻腔投与用組成 |
US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
ATE193892T1 (de) * | 1993-06-29 | 2000-06-15 | Ferring Bv | Synthese zyklischer peptide |
US5500413A (en) * | 1993-06-29 | 1996-03-19 | Ferring Ab | Process for manufacture of 1-deamino-8-D-arginine vasopressin |
US5674850A (en) * | 1993-12-23 | 1997-10-07 | Ferring Ab | High purity desmopressin produced in large single batches |
SE9400918L (sv) * | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
US5763398A (en) * | 1996-06-20 | 1998-06-09 | Ferring B.V. | Nasal administration of desmopressin |
US5922680A (en) * | 1996-10-23 | 1999-07-13 | Ferring, B.V. | Stabilized composition for oral administration of peptides |
JP2006501150A (ja) * | 2002-05-03 | 2006-01-12 | アベシア・リミテッド | ペプチド合成のためのプロセス |
CA2736799A1 (en) | 2008-08-25 | 2010-03-11 | Burnham Institute For Medical Research | Conserved hemagglutinin epitope, antibodies to the epitope, and methods of use |
EP2346529B1 (en) | 2008-11-12 | 2016-02-10 | Theraclone Sciences, Inc. | Human m2e peptide immunogens |
WO2010135277A2 (en) | 2009-05-18 | 2010-11-25 | Brown University | Cyclic-glur6 analogs, methods of treatment and use |
DK3154561T3 (da) | 2014-06-12 | 2019-10-07 | Ra Pharmaceuticals Inc | Modulering af komplementaktivitet |
LT3250230T (lt) | 2015-01-28 | 2021-12-27 | Ra Pharmaceuticals, Inc. | Komplemento aktyvumo moduliatoriai |
WO2016167291A1 (ja) | 2015-04-13 | 2016-10-20 | 国立研究開発法人産業技術総合研究所 | 環状化サイトカイン及びその製法 |
WO2017083362A1 (en) | 2015-11-09 | 2017-05-18 | Trustees Of Tufts College | Compounds and methods for treating pain |
SG11201804721SA (en) | 2015-12-16 | 2018-07-30 | Ra Pharmaceuticals Inc | Modulators of complement activity |
JP7301741B2 (ja) | 2016-12-07 | 2023-07-03 | ラ ファーマシューティカルズ インコーポレイテッド | 補体活性のモジュレータ |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3929758A (en) * | 1974-09-12 | 1975-12-30 | Armour Pharma | Cyclization of cysteine-containing peptides |
-
1975
- 1975-11-12 US US05/631,408 patent/US4033940A/en not_active Expired - Lifetime
-
1976
- 1976-10-14 JP JP51123378A patent/JPS5259179A/ja active Granted
- 1976-10-22 DE DE19762647843 patent/DE2647843A1/de not_active Ceased
- 1976-10-26 GB GB44382/76A patent/GB1568981A/en not_active Expired
- 1976-11-12 FR FR7634097A patent/FR2331553A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
US4033940A (en) | 1977-07-05 |
FR2331553A1 (fr) | 1977-06-10 |
DE2647843A1 (de) | 1977-05-26 |
FR2331553B1 (US07655688-20100202-C00086.png) | 1980-11-28 |
JPS6140680B2 (US07655688-20100202-C00086.png) | 1986-09-10 |
JPS5259179A (en) | 1977-05-16 |
Similar Documents
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---|---|---|
GB1568981A (en) | Cyclization of peptides | |
US3929758A (en) | Cyclization of cysteine-containing peptides | |
US3926938A (en) | Synthesis of salmon calcitonin | |
US4401593A (en) | Glycine - 8 calcitonin | |
US4217268A (en) | Synthesis of peptides | |
US4606856A (en) | [Des-1-amino, 8-glycine]calcitonin | |
US4537716A (en) | Des-serine2 or des-glycine2 -leucine22 calcitonin | |
US4397780A (en) | Leucine22 -calcitonin | |
US4622386A (en) | [1,7-di-alanine]calcitonin | |
US4212795A (en) | Cyclization of peptides | |
US4497731A (en) | Glycine 8-des-tyrosine 22 calcitonin | |
US4604238A (en) | Analogs of calcitonin | |
US4764589A (en) | [N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin | |
US4659804A (en) | (Bis-1,7-S-acetamidomethyl-L-cysteine)salmon calcitonin | |
US4639510A (en) | (1-S-acetamidomethyl cysteine, 7-alanine)calcitonin | |
US4632978A (en) | 6-serine, des-19-leucine calcitonin | |
US4528132A (en) | [16-Alanine]calcitonin | |
US5001222A (en) | Des-17-histidine-calcitonin | |
US4746728A (en) | 8-glycine, des-19-leucine-calcitonin | |
US4391747A (en) | Des asparagine-3-calcitonin | |
US4764590A (en) | Des-19-leucine, 20-glutamine, 21-threonine-calcitonin | |
US4820804A (en) | Analogs of [1,7-di-alanine, des-19-leucine]calcitonin | |
US4451395A (en) | Des-serine2 -des-tyrosine22 calcitonin | |
US4764591A (en) | Des-19-leucine, 20-glutamine, 21-threonine, 22-tyrosine-calcitonin | |
US4639509A (en) | [16,19-Di-alanine] calcitonin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |