GB1559920A - Process and device for the production of frozen granulates - Google Patents

Process and device for the production of frozen granulates Download PDF

Info

Publication number
GB1559920A
GB1559920A GB53984/77A GB5398477A GB1559920A GB 1559920 A GB1559920 A GB 1559920A GB 53984/77 A GB53984/77 A GB 53984/77A GB 5398477 A GB5398477 A GB 5398477A GB 1559920 A GB1559920 A GB 1559920A
Authority
GB
United Kingdom
Prior art keywords
liquid
cooling agent
frozen
granulates
frozen granulates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53984/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1559920A publication Critical patent/GB1559920A/en
Expired legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
    • A23B4/00—General methods for preserving meat, sausages, fish or fish products
    • A23B4/03—Drying; Subsequent reconstitution
    • A23B4/037—Freeze-drying, i.e. cryodessication, lyophilisation; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
    • A23B4/00—General methods for preserving meat, sausages, fish or fish products
    • A23B4/06—Freezing; Subsequent thawing; Cooling
    • A23B4/062—Freezing; Subsequent thawing; Cooling the materials being transported through or in the apparatus with or without shaping, e.g. in the form of powder, granules or flakes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/36—Freezing; Subsequent thawing; Cooling
    • A23L3/37—Freezing; Subsequent thawing; Cooling with addition of or treatment with chemicals
    • A23L3/375—Freezing; Subsequent thawing; Cooling with addition of or treatment with chemicals with direct contact between the food and the chemical, e.g. liquid nitrogen, at cryogenic temperature
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/40—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
    • A23L3/44—Freeze-drying
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25C—PRODUCING, WORKING OR HANDLING ICE
    • F25C1/00—Producing ice
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Thermal Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Combustion & Propulsion (AREA)
  • Drying Of Solid Materials (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Confectionery (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Glanulating (AREA)
GB53984/77A 1976-12-30 1977-12-28 Process and device for the production of frozen granulates Expired GB1559920A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762659546 DE2659546A1 (de) 1976-12-30 1976-12-30 Verfahren zur herstellung von gefrorenen granulaten

Publications (1)

Publication Number Publication Date
GB1559920A true GB1559920A (en) 1980-01-30

Family

ID=5997030

Family Applications (1)

Application Number Title Priority Date Filing Date
GB53984/77A Expired GB1559920A (en) 1976-12-30 1977-12-28 Process and device for the production of frozen granulates

Country Status (18)

Country Link
JP (1) JPS53114783A (xx)
AR (1) AR214108A1 (xx)
AT (1) AT356498B (xx)
AU (1) AU506746B2 (xx)
BE (1) BE862370A (xx)
CA (1) CA1106686A (xx)
CH (1) CH625332A5 (xx)
DD (1) DD133295A5 (xx)
DE (1) DE2659546A1 (xx)
FI (1) FI773941A (xx)
FR (1) FR2375901A1 (xx)
GB (1) GB1559920A (xx)
IE (1) IE46022B1 (xx)
IL (1) IL53695A0 (xx)
IT (1) IT1089419B (xx)
NL (1) NL7714401A (xx)
SE (1) SE7714822L (xx)
ZA (1) ZA777184B (xx)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0461160A1 (en) * 1989-03-01 1991-12-18 FRENCH, Andrew Boyd Snowmaking method and device
EP0621453A1 (en) * 1993-04-20 1994-10-26 E.I. Du Pont De Nemours And Company Method and apparatus for producing frozen particles using an entrapment zone of atomized cryogenic liquid droplets
EP0731326A2 (en) * 1995-03-09 1996-09-11 The Boc Group, Inc. Process fluid cooling method and apparatus
EP0945173A1 (de) * 1998-03-25 1999-09-29 Herbert Dressler Vorrichtung und Verfahren zur Herstellung von pulverförmigen Stoffen
WO1999065600A1 (en) * 1998-06-02 1999-12-23 Leiv Eiriksson Nyfotek As A method for formulating particles
WO2001023814A1 (en) * 1999-09-30 2001-04-05 Saitec S.R.L. Method and system for cooling and effecting a change in state of a liquid mixture
EP1400279A1 (de) * 2002-09-19 2004-03-24 MESSER GRIESHEIM GmbH System zum Mikropelletieren und Pulverisieren von Flüssigkeiten
WO2005053440A1 (en) * 2003-12-03 2005-06-16 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Method and plant for cooling fluids by direct contact with liquefied gases
WO2006008006A1 (en) 2004-07-23 2006-01-26 Bayer Technology Services Gmbh Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
EP2065660A2 (en) * 2007-11-30 2009-06-03 Whirlpool Corporation Method and device for producing ice droplets on demand
EP2074366A2 (en) * 2006-10-16 2009-07-01 Agresearch Limited Improvements in spray freeze drying
US8142795B2 (en) 2008-07-09 2012-03-27 Sanofi Pasteur Stabilizer and vaccine composition comprising one or more live attenuated flaviviruses
CN103123196A (zh) * 2013-02-06 2013-05-29 邹杰 一种蓄冷设备
WO2013076401A1 (fr) * 2011-11-24 2013-05-30 L'air Liquide,Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Dispositif de refroidissement de produits en vrac
US9295721B2 (en) 2008-03-05 2016-03-29 Sanofi Pasteur Sa Process for stabilizing an adjuvant containing vaccine composition
CN106113314A (zh) * 2016-08-15 2016-11-16 浙江心源科技有限公司 一种喷雾结晶造粒装置及其造粒方法
CN109820130A (zh) * 2019-04-03 2019-05-31 河南工业大学 一种可溶性膳食纤维提取装置
CN112774571A (zh) * 2020-12-26 2021-05-11 深圳万和制药有限公司 高均匀性大粒径微丸的分散冷凝生产工艺
WO2022047366A1 (en) * 2020-08-31 2022-03-03 Cornell University Systems and methods for rapidly freezing a liquid

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042955A1 (de) * 1980-11-14 1982-10-21 Helmut 7702 Gottmadingen Ruh Verfahren und vorrichtung zum aufbereiten frischer kraeuter oder kraeutermischungen sowie formkoerper daraus
FR2566515B1 (fr) * 1984-06-22 1987-03-27 Air Liquide Procede et installation de refroidissement, au moyen d'un fluide frigorigene d'une poudre
US4704873A (en) * 1985-11-14 1987-11-10 Taiyo Sanso Co., Ltd. Method and apparatus for producing microfine frozen particles
DE69005800T2 (de) * 1989-05-01 1994-05-19 Alkermes Inc Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekülen.
JPH0753704Y2 (ja) * 1989-06-05 1995-12-13 大陽酸素株式会社 凍結粒製造装置
JPH089582Y2 (ja) * 1990-08-31 1996-03-21 大陽酸素株式会社 凍結粒製造装置
DE4112890A1 (de) * 1991-04-19 1992-10-22 Abony Szuecs Eva Verfahren und vorrichtung zum reinigen von oberflaechen, insbesondere von empfindlichen oberflaechen
JPH05115853A (ja) * 1991-04-19 1993-05-14 Eva Abony Szucs 鋭敏な表面を洗浄する方法および装置
DE4344393C2 (de) * 1993-12-24 1998-10-01 Ftd Foam Tech Dev Gmbh Einrichtung zum Herstellen von Speiseeis, gefrorenen Dessert- und Fruchtmassen, Tortenmassen, Teigmassen, aus mehreren schwer mischbaren fluiden Matrizes, welche aus wenigstens einer Stoffkomponente bestehen
JP5183068B2 (ja) 2003-12-22 2013-04-17 フィンレイ，ウォーレン，エイチ 大気噴出凍結乾燥法による粉末形成
US9945611B2 (en) 2010-08-04 2018-04-17 Ima Life North America Inc. Bulk freeze drying using spray freezing and agitated drying
ITBS20110076A1 (it) * 2011-05-25 2012-11-26 K190 S R L Apparato e procedimento per la preparazione di gelato o prodotti alimentari affini
JP5837670B2 (ja) * 2014-10-24 2015-12-24 アイエムエー ライフ ノース アメリカ インコーポレーテッド 噴霧凍結および撹拌乾燥を使用するバルク・フリーズドライ
CN105597622B (zh) * 2016-03-09 2017-11-21 苏州大学 结冰温度可控的用于制备微米级冰球颗粒的喷雾冷冻塔
DE202016106243U1 (de) * 2016-09-21 2016-11-17 Dressler Group GmbH & Co. KG Vorrichtung zur Herstellung von pulverförmigen Kunststoffen mit möglichst kugelförmiger Struktur
DE102018002750B8 (de) * 2018-04-06 2020-09-24 Messer France S.A.S. Vorrichtung zum Kühlen von Produkten
CN108709369A (zh) * 2018-04-20 2018-10-26 大连工业大学 一种超声波喷雾冷冻干燥装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2751687A (en) * 1952-05-21 1956-06-26 Proctor Drying And Freezing Co Process and apparatus for producing stabilized products

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0461160A1 (en) * 1989-03-01 1991-12-18 FRENCH, Andrew Boyd Snowmaking method and device
EP0461160A4 (en) * 1989-03-01 1992-01-15 Andrew Boyd French Snowmaking method and device
EP0621453A1 (en) * 1993-04-20 1994-10-26 E.I. Du Pont De Nemours And Company Method and apparatus for producing frozen particles using an entrapment zone of atomized cryogenic liquid droplets
EP0871001A3 (en) * 1993-04-20 2000-01-05 Dade Chemistry Systems Inc. Method and apparatus for producing frozen particles using an entrapment zone of atomized cryogenic liquid droplets
EP0731326A2 (en) * 1995-03-09 1996-09-11 The Boc Group, Inc. Process fluid cooling method and apparatus
EP0731326A3 (xx) * 1995-03-09 1996-09-25 Boc Group Inc
EP0945173A1 (de) * 1998-03-25 1999-09-29 Herbert Dressler Vorrichtung und Verfahren zur Herstellung von pulverförmigen Stoffen
WO1999065600A1 (en) * 1998-06-02 1999-12-23 Leiv Eiriksson Nyfotek As A method for formulating particles
WO2001023814A1 (en) * 1999-09-30 2001-04-05 Saitec S.R.L. Method and system for cooling and effecting a change in state of a liquid mixture
US6666035B1 (en) 1999-09-30 2003-12-23 Saitec S.R.L. Method and system for cooling and effecting a change in state of a liquid mixture
EP1400279A1 (de) * 2002-09-19 2004-03-24 MESSER GRIESHEIM GmbH System zum Mikropelletieren und Pulverisieren von Flüssigkeiten
CN1889859B (zh) * 2003-12-03 2010-06-02 乔治洛德方法研究和开发液化空气有限公司 通过与液化气体直接接触以冷却流体的方法和设备
AU2004294805B2 (en) * 2003-12-03 2010-04-22 L'air Liquide Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Method and plant for cooling fluids by direct contact with liquefied gases
WO2005053440A1 (en) * 2003-12-03 2005-06-16 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Method and plant for cooling fluids by direct contact with liquefied gases
WO2006008006A1 (en) 2004-07-23 2006-01-26 Bayer Technology Services Gmbh Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
US7836606B2 (en) 2004-07-23 2010-11-23 Bayer Technology Services Gmbh Sterile freezing, drying, storing, assaying and filling process
EP2074366A4 (en) * 2006-10-16 2014-05-21 Agres Ltd IMPROVED SPRAY FREEZE DRYING
EP2074366A2 (en) * 2006-10-16 2009-07-01 Agresearch Limited Improvements in spray freeze drying
EP2065660A3 (en) * 2007-11-30 2014-01-08 Whirlpool Corporation Method and device for producing ice droplets on demand
EP2065660A2 (en) * 2007-11-30 2009-06-03 Whirlpool Corporation Method and device for producing ice droplets on demand
US9878028B2 (en) 2008-03-05 2018-01-30 Sanofi Pasteur Sa Process for stabilizing an adjuvant containing vaccine composition
US9295721B2 (en) 2008-03-05 2016-03-29 Sanofi Pasteur Sa Process for stabilizing an adjuvant containing vaccine composition
US8142795B2 (en) 2008-07-09 2012-03-27 Sanofi Pasteur Stabilizer and vaccine composition comprising one or more live attenuated flaviviruses
AU2012342292B2 (en) * 2011-11-24 2017-04-13 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Device for cooling bulk products
WO2013076401A1 (fr) * 2011-11-24 2013-05-30 L'air Liquide,Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Dispositif de refroidissement de produits en vrac
FR2983286A1 (fr) * 2011-11-24 2013-05-31 Air Liquide Dispositif de refroidissement de produits en vrac
CN103123196B (zh) * 2013-02-06 2015-08-26 邹杰 一种蓄冷设备
CN103123196A (zh) * 2013-02-06 2013-05-29 邹杰 一种蓄冷设备
CN106113314A (zh) * 2016-08-15 2016-11-16 浙江心源科技有限公司 一种喷雾结晶造粒装置及其造粒方法
CN106113314B (zh) * 2016-08-15 2019-06-21 浙江心源科技有限公司 一种喷雾结晶造粒装置及其造粒方法
CN109820130A (zh) * 2019-04-03 2019-05-31 河南工业大学 一种可溶性膳食纤维提取装置
CN109820130B (zh) * 2019-04-03 2022-09-16 河南工业大学 一种可溶性膳食纤维提取装置
WO2022047366A1 (en) * 2020-08-31 2022-03-03 Cornell University Systems and methods for rapidly freezing a liquid
CN112774571A (zh) * 2020-12-26 2021-05-11 深圳万和制药有限公司 高均匀性大粒径微丸的分散冷凝生产工艺

Also Published As

Publication number Publication date
JPS53114783A (en) 1978-10-06
FI773941A (fi) 1978-07-01
ZA777184B (en) 1978-10-25
IE46022B1 (en) 1983-01-26
AU506746B2 (en) 1980-01-24
BE862370A (fr) 1978-06-27
SE7714822L (sv) 1978-07-01
IT1089419B (it) 1985-06-18
AR214108A1 (es) 1979-04-30
NL7714401A (nl) 1978-07-04
DD133295A5 (de) 1978-12-27
DE2659546A1 (de) 1978-07-13
CA1106686A (en) 1981-08-11
ATA940677A (de) 1979-09-15
IE46022L (en) 1978-06-30
IL53695A0 (en) 1978-03-10
FR2375901A1 (fr) 1978-07-28
CH625332A5 (en) 1981-09-15
AU3192277A (en) 1979-06-28
AT356498B (de) 1980-04-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee