GB1557594A - N pheny n 2 aminocyclohepty amides and thioamides - Google Patents

N pheny n 2 aminocyclohepty amides and thioamides

Info

Publication number
GB1557594A
GB1557594A GB46748/77A GB4674877A GB1557594A GB 1557594 A GB1557594 A GB 1557594A GB 46748/77 A GB46748/77 A GB 46748/77A GB 4674877 A GB4674877 A GB 4674877A GB 1557594 A GB1557594 A GB 1557594A
Authority
GB
United Kingdom
Prior art keywords
aminocyclohepty
thioamides
pheny
amides
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB46748/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1557594A publication Critical patent/GB1557594A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/06—Oxalic acid
    • C07C55/07—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid

Abstract

Novel N-(aminocycloheptyl)-N-alkanoyl anilides of the formula <IMAGE> in which the substituents are described in Claim 1, are prepared. These compounds are obtained by acylating an appropriately substituted N-[2-(disubstituted amino)-cycloheptyl]aniline with an acid anhydride or an acid halide. The corresponding N-oxides are prepared from compounds of the formula I by oxidation with a percarbonic acid. The compounds which are obtained can be used as antidepressants.
GB46748/77A 1977-03-21 1977-11-10 N pheny n 2 aminocyclohepty amides and thioamides Expired GB1557594A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77959377A 1977-03-21 1977-03-21

Publications (1)

Publication Number Publication Date
GB1557594A true GB1557594A (en) 1979-12-12

Family

ID=25116918

Family Applications (2)

Application Number Title Priority Date Filing Date
GB46748/77A Expired GB1557594A (en) 1977-03-21 1977-11-10 N pheny n 2 aminocyclohepty amides and thioamides
GB46583/78A Expired GB1557595A (en) 1977-03-21 1977-11-10 N phenyl n 2 aminocycloheptyl amides and compositions containing such compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB46583/78A Expired GB1557595A (en) 1977-03-21 1977-11-10 N phenyl n 2 aminocycloheptyl amides and compositions containing such compounds

Country Status (9)

Country Link
JP (1) JPS53116347A (en)
AU (1) AU511540B2 (en)
BE (1) BE861352A (en)
CH (4) CH636341A5 (en)
DE (1) DE2749213A1 (en)
FR (1) FR2384744A1 (en)
GB (2) GB1557594A (en)
NL (1) NL7712898A (en)
SE (3) SE442198B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines

Also Published As

Publication number Publication date
BE861352A (en) 1978-05-30
NL7712898A (en) 1978-09-25
GB1557595A (en) 1979-12-12
SE8204695L (en) 1982-08-13
SE8204694D0 (en) 1982-08-13
SE442198B (en) 1985-12-09
SE8204695D0 (en) 1982-08-13
DE2749213C2 (en) 1988-09-08
JPS6146471B2 (en) 1986-10-14
CH636341A5 (en) 1983-05-31
AU511540B2 (en) 1980-08-21
CH636604A5 (en) 1983-06-15
CH636597A5 (en) 1983-06-15
JPS53116347A (en) 1978-10-11
AU3049077A (en) 1979-05-17
DE2749213A1 (en) 1978-10-05
SE7713440L (en) 1978-09-22
FR2384744A1 (en) 1978-10-20
FR2384744B1 (en) 1980-08-22
CH637110A5 (en) 1983-07-15
SE8204694L (en) 1982-08-13

Similar Documents

Publication Publication Date Title
NO800657L (en) NON-IONOGENT XENTIC CONTRACTOR.
FI853717L (en) 3-AMINO-2-BENZOYL-ACRYLIC SYRADER OCH FOERFARANDE FOER DERAS FRAMSTAELLNING.
ES8104990A1 (en) Use as fungicides of N-(3-pyridylmethyl)-N-acyl anilines
GB1410516A (en) Phenoxy-carboxylic acid amides
ES450943A1 (en) 3-Pyridyl-oxy-alkanecarboxylic acid amides
GB1494436A (en) O-aminosulphonyl-glycolic anilides
GB1557594A (en) N pheny n 2 aminocyclohepty amides and thioamides
IL63450A (en) N-(1,2,3-thiadiazol-4-yl)anilides,their preparation and their use as microbicides and agents for such use
ES553560A0 (en) PROCEDURE FOR OBTAINING SUBSTITUTED 5-AMINO-1-PHENYLPIRAZOLES
GB1554176A (en) Manufacture of aliphatic 2-amino-1-alcohols
GB2001053A (en) Insecticidal substituted benzoyl ureas
SE7713439L (en) ALKANOYLANILIDE DERIVATIVES
SE7704594L (en) 2-IMINOTIAZOLIDIER AND THIAZOLINES
ES2029033T3 (en) PROCEDURE FOR PREPARING DERIVATIVES OF N- (1H-INDOL-4-IL) -BENZAMIDE.
GB994614A (en) Trifluoromethyl chloranilide compounds
ES413391A1 (en) Preparation of n-tertiary aminoalkyl-2-alkoxy benzamides and benzoic anhydride derivatives produced during it
GB1321592A (en) Disubstituted 2,4,6-triidobenzoic acid halides useful in the preparation of x-ray contrast agents
GB963820A (en) Phenylpiperidylalkyl anilides
SE7807729L (en) LEG SLIDING DERIVATIVES
ES429202A1 (en) Procedure for the obtaining of N- (2- (n&#39;-ciclohexil-n&#39;-methyl-n&#39;-methylen) -4,6-dibromo-phenyl) -3-metoxy-4-propionoxy-benzamide, hydrochloride. (Machine-translation by Google Translate, not legally binding)
BR8108480A (en) PROCESS FOR THE PRODUCTION OF N- (SULFENAMIDE) -ACYLISOCIANATES AND ITS APPLICATION
ES410425A1 (en) Procedure for obtaining N- (2-hydroxyethyl) palmitamide. (Machine-translation by Google Translate, not legally binding)
GB1113972A (en) Improvements in or relating to aryloxy propanols and the manufacture thereof
ES429203A1 (en) Process for the obtaining of N- (2- (n&#39;-ciclohexil-n&#39;-methyl-n&#39;-methylen) -4,6-dibromo-phenyl) -3-etoxy-4-isobutirexy-benzamide, hydrochloride. (Machine-translation by Google Translate, not legally binding)
ES429200A1 (en) Process for the obtaining of N- (2- (n&#39;-ciclohexil-n&#39;-methyl-n&#39;-methylen) -4,6-dibromo-phenyl) -3-etoxy-4-acetoxy-benzamide, hydrochloride. (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee