GB994614A - Trifluoromethyl chloranilide compounds - Google Patents
Trifluoromethyl chloranilide compoundsInfo
- Publication number
- GB994614A GB994614A GB47033/63A GB4703363A GB994614A GB 994614 A GB994614 A GB 994614A GB 47033/63 A GB47033/63 A GB 47033/63A GB 4703363 A GB4703363 A GB 4703363A GB 994614 A GB994614 A GB 994614A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trifluoromethyl
- acid
- chloroanilide
- crotonic
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of general formula <FORM:0994614/C2/1> in which R is hydrogen or methyl and R1 is n-butyl, cyclohexyl or benzyl; and their preparation by (1) reacting N-acrylic acid- or N - crotonic acid - 2 - trifluoromethyl - 4- chloro-anilide with n-butylamine, cyclohexylamine or benzylamine at elevated temperature; or (2) heating with at least two molar proportions of n - butylamine, cyclohexylamine or benzylamine an N - carboxylic acid - 2 - trifluoromethyl - 4 - chloroanilide which can be converted into the N-acrylic or crotonic acidderivative by heating with an amine. Acid addition salts are obtained. N - Crotonic acid - 2 - trifluoromethyl - 4-chloroanilide and N - (b -bromopropionic acid)-2 - trifluoromethyl - 4 - chloroanilide are prepared from the amine and acid chlorides.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF38431A DE1232159B (en) | 1962-11-30 | 1962-11-30 | Process for the preparation of beta-amino acid anilides containing trifluoromethyl groups |
Publications (1)
Publication Number | Publication Date |
---|---|
GB994614A true GB994614A (en) | 1965-06-10 |
Family
ID=7097337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB47033/63A Expired GB994614A (en) | 1962-11-30 | 1963-11-28 | Trifluoromethyl chloranilide compounds |
Country Status (6)
Country | Link |
---|---|
AT (1) | AT244940B (en) |
CH (1) | CH428753A (en) |
DE (1) | DE1232159B (en) |
FR (1) | FR3258M (en) |
GB (1) | GB994614A (en) |
SE (1) | SE301644B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2177695A (en) * | 1985-07-15 | 1987-01-28 | Roussel Lab Ltd | Aminoalkylamide derivatives |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH627446A5 (en) * | 1978-01-17 | 1982-01-15 | Debiopharm Sa | NEW BENZAMIDE DERIVATIVES. |
-
1962
- 1962-11-30 DE DEF38431A patent/DE1232159B/en active Pending
-
1963
- 1963-11-18 CH CH1407763A patent/CH428753A/en unknown
- 1963-11-21 AT AT932963A patent/AT244940B/en active
- 1963-11-28 GB GB47033/63A patent/GB994614A/en not_active Expired
- 1963-11-29 SE SE13265/63A patent/SE301644B/xx unknown
-
1964
- 1964-02-28 FR FR965589A patent/FR3258M/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2177695A (en) * | 1985-07-15 | 1987-01-28 | Roussel Lab Ltd | Aminoalkylamide derivatives |
GB2177695B (en) * | 1985-07-15 | 1989-07-19 | Roussel Lab Ltd | Aminoalkylamide derivatives |
Also Published As
Publication number | Publication date |
---|---|
SE301644B (en) | 1968-06-17 |
CH428753A (en) | 1967-01-31 |
DE1232159B (en) | 1967-01-12 |
FR3258M (en) | 1965-04-20 |
AT244940B (en) | 1966-02-10 |
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