SE7713439L - ALKANOYLANILIDE DERIVATIVES - Google Patents

ALKANOYLANILIDE DERIVATIVES

Info

Publication number
SE7713439L
SE7713439L SE7713439A SE7713439A SE7713439L SE 7713439 L SE7713439 L SE 7713439L SE 7713439 A SE7713439 A SE 7713439A SE 7713439 A SE7713439 A SE 7713439A SE 7713439 L SE7713439 L SE 7713439L
Authority
SE
Sweden
Prior art keywords
compounds
alkanoylanilide
derivatives
aminocyclopentyl
oxides
Prior art date
Application number
SE7713439A
Other languages
Swedish (sv)
Other versions
SE441444B (en
Inventor
J Szmuszkovicz
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE7713439L publication Critical patent/SE7713439L/en
Publication of SE441444B publication Critical patent/SE441444B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups

Abstract

Novel N-(2-aminocyclopentyl)-N-alkanoyl anilides and 2-N-oxides thereof of the formula: <IMAGE> in which the substituents are defined in Claims 1 and 10, are prepared. These compounds are obtained by acylating N-(2-aminocyclopentyl)aniline on the nitrogen atom either with an anhydride of an organic carboxylic acid of the formula R-COOH or with a R-C (O)-chloride or R-C (O)-bromide. The corresponding N-oxides are prepared from these acylated compounds by oxidation with a percarbonic acid. The novel compounds which are obtained can be used as antidepressants.
SE7713439A 1976-11-30 1977-11-28 PROCEDURE FOR PREPARING NEW N- (2AMINOCYCLOPENTYL) ALKANOYLANILIDES SE441444B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74619176A 1976-11-30 1976-11-30
US77759977A 1977-03-15 1977-03-15

Publications (2)

Publication Number Publication Date
SE7713439L true SE7713439L (en) 1978-05-31
SE441444B SE441444B (en) 1985-10-07

Family

ID=27114572

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7713439A SE441444B (en) 1976-11-30 1977-11-28 PROCEDURE FOR PREPARING NEW N- (2AMINOCYCLOPENTYL) ALKANOYLANILIDES

Country Status (8)

Country Link
JP (1) JPS5368748A (en)
AU (1) AU511200B2 (en)
CH (1) CH636340A5 (en)
DE (1) DE2749214A1 (en)
FR (1) FR2384495A1 (en)
GB (2) GB1560219A (en)
NL (1) NL7712899A (en)
SE (1) SE441444B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7803442A (en) * 1978-02-09 1979-08-13 Upjohn Co METHODS FOR PREPARING AND USING AMINO-CYCLOALIPHATIC AMIDES.
IE58999B1 (en) * 1985-07-22 1993-12-15 Rolland Sa A Novel N-oxyde of NN-dimethyl ethylamine, a process for it's production and the pharmaceutical compositions containing it

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines

Also Published As

Publication number Publication date
FR2384495A1 (en) 1978-10-20
AU3048977A (en) 1979-05-17
NL7712899A (en) 1978-06-01
JPS5368748A (en) 1978-06-19
DE2749214C2 (en) 1987-11-05
GB1560218A (en) 1980-01-30
GB1560219A (en) 1980-01-30
FR2384495B1 (en) 1980-07-25
SE441444B (en) 1985-10-07
DE2749214A1 (en) 1978-06-01
AU511200B2 (en) 1980-07-31
CH636340A5 (en) 1983-05-31

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