GB1550496A - 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications - Google Patents
1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applicationsInfo
- Publication number
- GB1550496A GB1550496A GB5440176A GB5440176A GB1550496A GB 1550496 A GB1550496 A GB 1550496A GB 5440176 A GB5440176 A GB 5440176A GB 5440176 A GB5440176 A GB 5440176A GB 1550496 A GB1550496 A GB 1550496A
- Authority
- GB
- United Kingdom
- Prior art keywords
- derivatives
- alkyl
- image
- canthine
- hexahydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 230000002490 cerebral effect Effects 0.000 abstract 2
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- -1 C2-C6 alkynyl radical Chemical group 0.000 abstract 1
- 206010054880 Vascular insufficiency Diseases 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000023577 vascular insufficiency disease Diseases 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5440176A GB1550496A (en) | 1976-12-31 | 1976-12-31 | 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications |
FR7737403A FR2376150A1 (fr) | 1976-12-31 | 1977-12-12 | Compositions therapeutiques a base de derives de l'hexahydro-1,2,3,3a,4,5-canthine |
DE19772758405 DE2758405A1 (de) | 1976-12-31 | 1977-12-28 | Arzneimittelzubereitung, enthaltend 1,2,3,3a,4,5-hexahydrocanthinderivate |
ES465606A ES465606A1 (es) | 1976-12-31 | 1977-12-30 | Procedimiento de preparacion de nuevos derivados de hexahi- dro-1,2,3,3a,4,5-cantina. |
CH1630777A CH627647A5 (en) | 1976-12-31 | 1978-01-01 | 1,2,3,3a,4,5-Hexahydrocanthine derivatives and therapeutic compositions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5440176A GB1550496A (en) | 1976-12-31 | 1976-12-31 | 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1550496A true GB1550496A (en) | 1979-08-15 |
Family
ID=10470892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5440176A Expired GB1550496A (en) | 1976-12-31 | 1976-12-31 | 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications |
Country Status (5)
Country | Link |
---|---|
CH (1) | CH627647A5 (enrdf_load_stackoverflow) |
DE (1) | DE2758405A1 (enrdf_load_stackoverflow) |
ES (1) | ES465606A1 (enrdf_load_stackoverflow) |
FR (1) | FR2376150A1 (enrdf_load_stackoverflow) |
GB (1) | GB1550496A (enrdf_load_stackoverflow) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT379594B (de) * | 1980-11-21 | 1986-01-27 | Synthelabo | Verfahren zur herstellung von neuen 2,3,3a,4,5,6hexahydro-1h-indolo(3,2,1-de)-(1,5-naphtyridin) -derivaten und ihre pharmazeutisch zulaessigen saeureadditionssalze |
US4835271A (en) * | 1985-06-28 | 1989-05-30 | Beecham-Wuelfing Gmbh & Co., Kg | Aminoalkyl secocanthine derivatives and their use |
US4837240A (en) * | 1986-07-01 | 1989-06-06 | Beecham-Wuelfing Gmbh & Co. Kg | Aminoalkyl secocanthine derivatives and their use |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2449449A2 (fr) * | 1978-09-27 | 1980-09-19 | Omnium Chimique Sa | Composes indoliques nouveaux utiles comme medicaments |
ES503557A0 (es) * | 1980-07-03 | 1982-04-01 | Omnichem Sa | Procedimiento de preparacion de alquil-3 tetrahidro-1,2,3, 3a-4h-indolo(3,2,1-de)-1,5-naftiridinas. |
FR2548668B1 (fr) * | 1983-07-05 | 1985-09-20 | Synthelabo | Derives d'hexahydro-indolo-naphtyridines, leur preparation et leur application en therapeutique |
FR2548667B1 (fr) * | 1983-07-05 | 1985-09-20 | Synthelabo | Derives de benz-indolo-naphtyridine, leur preparation et leur application en therapeutique |
GB8416724D0 (en) * | 1984-06-30 | 1984-08-01 | Sorbio Sa Lab | Active compounds |
US4624954A (en) * | 1985-12-20 | 1986-11-25 | American Home Products Corporation | 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments |
CA1329597C (en) * | 1986-12-22 | 1994-05-17 | Dagmar Hoeltje | Derivatives of tetrahydropyrido[1,2-a]indole |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI751840A7 (enrdf_load_stackoverflow) * | 1974-09-24 | 1976-03-25 | Synthelabo | |
HU171163B (hu) * | 1974-09-27 | 1977-11-28 | Richter Gedeon Vegyeszet | Sposob poluchenija proizvodnykh trans eburnamenina |
-
1976
- 1976-12-31 GB GB5440176A patent/GB1550496A/en not_active Expired
-
1977
- 1977-12-12 FR FR7737403A patent/FR2376150A1/fr active Granted
- 1977-12-28 DE DE19772758405 patent/DE2758405A1/de not_active Ceased
- 1977-12-30 ES ES465606A patent/ES465606A1/es not_active Expired
-
1978
- 1978-01-01 CH CH1630777A patent/CH627647A5/fr not_active IP Right Cessation
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT379594B (de) * | 1980-11-21 | 1986-01-27 | Synthelabo | Verfahren zur herstellung von neuen 2,3,3a,4,5,6hexahydro-1h-indolo(3,2,1-de)-(1,5-naphtyridin) -derivaten und ihre pharmazeutisch zulaessigen saeureadditionssalze |
US4835271A (en) * | 1985-06-28 | 1989-05-30 | Beecham-Wuelfing Gmbh & Co., Kg | Aminoalkyl secocanthine derivatives and their use |
US4987137A (en) * | 1985-06-28 | 1991-01-22 | Beecham Wuelfing Gmbh & Co., Kg | Certain 6,7,8,9-tetrahydropyrido[1,2-α]indoles and their use for the treatment of cerebrovascular disorders |
US4837240A (en) * | 1986-07-01 | 1989-06-06 | Beecham-Wuelfing Gmbh & Co. Kg | Aminoalkyl secocanthine derivatives and their use |
Also Published As
Publication number | Publication date |
---|---|
FR2376150B1 (enrdf_load_stackoverflow) | 1980-10-24 |
DE2758405A1 (de) | 1978-07-13 |
ES465606A1 (es) | 1978-09-16 |
FR2376150A1 (fr) | 1978-07-28 |
CH627647A5 (en) | 1982-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |