GB1542749A - N,n-dimethyl-aminoalkyl-3',4'-dihalo-anilides methods for their preparation and compositions containing them - Google Patents
N,n-dimethyl-aminoalkyl-3',4'-dihalo-anilides methods for their preparation and compositions containing themInfo
- Publication number
- GB1542749A GB1542749A GB7746751A GB4675177A GB1542749A GB 1542749 A GB1542749 A GB 1542749A GB 7746751 A GB7746751 A GB 7746751A GB 4675177 A GB4675177 A GB 4675177A GB 1542749 A GB1542749 A GB 1542749A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- anilides
- groups
- image
- chain consisting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940051881 anilide analgesics and antipyretics Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003931 anilides Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 238000007126 N-alkylation reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- QKIUAMUSENSFQQ-UHFFFAOYSA-N dimethylazanide Chemical compound C[N-]C QKIUAMUSENSFQQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74686376A | 1976-12-02 | 1976-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1542749A true GB1542749A (en) | 1979-03-21 |
Family
ID=25002691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7746751A Expired GB1542749A (en) | 1976-12-02 | 1977-11-10 | N,n-dimethyl-aminoalkyl-3',4'-dihalo-anilides methods for their preparation and compositions containing them |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5371024A (enrdf_load_stackoverflow) |
| AU (1) | AU509345B2 (enrdf_load_stackoverflow) |
| BE (1) | BE861455A (enrdf_load_stackoverflow) |
| CH (1) | CH636596A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2751905A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2372796A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1542749A (enrdf_load_stackoverflow) |
| NL (1) | NL7713204A (enrdf_load_stackoverflow) |
| SE (2) | SE441445B (enrdf_load_stackoverflow) |
-
1977
- 1977-11-07 AU AU30376/77A patent/AU509345B2/en not_active Expired
- 1977-11-10 GB GB7746751A patent/GB1542749A/en not_active Expired
- 1977-11-21 DE DE19772751905 patent/DE2751905A1/de active Granted
- 1977-11-22 CH CH1429377A patent/CH636596A5/de not_active IP Right Cessation
- 1977-11-28 SE SE7713442A patent/SE441445B/sv not_active IP Right Cessation
- 1977-11-30 NL NL7713204A patent/NL7713204A/xx not_active Application Discontinuation
- 1977-11-30 FR FR7736186A patent/FR2372796A1/fr active Granted
- 1977-12-02 BE BE183134A patent/BE861455A/xx not_active IP Right Cessation
- 1977-12-02 JP JP14491777A patent/JPS5371024A/ja active Granted
-
1983
- 1983-07-28 SE SE8304187A patent/SE8304187D0/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU3037677A (en) | 1979-05-17 |
| SE8304187L (sv) | 1983-07-28 |
| BE861455A (fr) | 1978-06-02 |
| FR2372796A1 (fr) | 1978-06-30 |
| JPS5371024A (en) | 1978-06-24 |
| AU509345B2 (en) | 1980-05-08 |
| DE2751905C2 (enrdf_load_stackoverflow) | 1987-06-11 |
| SE7713442L (sv) | 1978-06-03 |
| CH636596A5 (en) | 1983-06-15 |
| NL7713204A (nl) | 1978-06-06 |
| JPS6220182B2 (enrdf_load_stackoverflow) | 1987-05-06 |
| SE8304187D0 (sv) | 1983-07-28 |
| DE2751905A1 (de) | 1978-06-08 |
| FR2372796B1 (enrdf_load_stackoverflow) | 1980-08-22 |
| SE441445B (sv) | 1985-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |