GB1540769A - Beta-lactam containing compounds and their preparation - Google Patents

Beta-lactam containing compounds and their preparation

Info

Publication number
GB1540769A
GB1540769A GB30609/76A GB3060976A GB1540769A GB 1540769 A GB1540769 A GB 1540769A GB 30609/76 A GB30609/76 A GB 30609/76A GB 3060976 A GB3060976 A GB 3060976A GB 1540769 A GB1540769 A GB 1540769A
Authority
GB
United Kingdom
Prior art keywords
beta
preparation
containing compounds
lactam containing
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30609/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1540769A publication Critical patent/GB1540769A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB30609/76A 1975-07-23 1976-07-22 Beta-lactam containing compounds and their preparation Expired GB1540769A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/598,461 US4013648A (en) 1975-07-23 1975-07-23 Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
GB1540769A true GB1540769A (en) 1979-02-14

Family

ID=24395629

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30609/76A Expired GB1540769A (en) 1975-07-23 1976-07-22 Beta-lactam containing compounds and their preparation

Country Status (6)

Country Link
US (4) US4013648A (enExample)
JP (1) JPS5214798A (enExample)
CA (2) CA1095908A (enExample)
DE (1) DE2633193A1 (enExample)
FR (2) FR2318637A1 (enExample)
GB (1) GB1540769A (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226866A (en) * 1972-11-06 1980-10-07 Merck & Co., Inc. Novel antibiotic analogues of cephalosporins
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4171439A (en) * 1975-04-11 1979-10-16 Bristol-Myers Company Antibacterial analogs of isocephalosporins
US4011216A (en) * 1975-04-11 1977-03-08 Bristol-Myers Company Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents
US4108992A (en) * 1975-05-10 1978-08-22 Beecham Group Limited Cephalosporin analogues and compositions
US4171438A (en) * 1975-07-23 1979-10-16 Bristol-Myers Company 0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins
US4187375A (en) * 1976-09-08 1980-02-05 Smithkline Corporation Process for preparing oxazine ring compounds
US4089956A (en) * 1976-09-08 1978-05-16 Smithkline Corporation 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof
US4203902A (en) * 1978-04-21 1980-05-20 Merck & Co., Inc. Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids
JPH02111750A (ja) * 1978-09-12 1990-04-24 Fujisawa Pharmaceut Co Ltd 酪酸誘導体
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
US4347355A (en) * 1980-02-21 1982-08-31 Abbott Laboratories Inhibitors of transpeptidase
US4338452A (en) * 1980-09-17 1982-07-06 Eli Lilly And Company 1-and 2-(1-Alkyl-1H-tetrazol-5-yl-methyl)-1H-tetrazol-5-thiols and 1-cyanomethyl tetrazole-5-thiol
WO1982001875A1 (en) * 1980-12-01 1982-06-10 Lab Abbott Inhibitors of transpeptidase
US4820817A (en) * 1984-09-10 1989-04-11 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid
AU583419B2 (en) * 1985-09-09 1989-04-27 Higuchi, Yoshinari 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
KR960002856B1 (ko) * 1987-03-09 1996-02-27 오쓰까 세이야꾸 가부시끼가이샤 2-옥사-이소세펨 화합물, 이를 함유하는 조성물 및 이의 제조방법
DK582788A (da) * 1987-10-22 1989-04-23 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, midler der indeholder dem og fremgangsmaader til fremstilling af dem
JP2993576B2 (ja) * 1991-03-11 1999-12-20 大塚化学株式会社 アレニルβ−ラクタム化合物及びその製造法
JP3775820B2 (ja) * 1995-03-10 2006-05-17 大塚化学ホールディングス株式会社 ハロゲン化β−ラクタム化合物の製造法
US6290689B1 (en) * 1999-10-22 2001-09-18 Corazón Technologies, Inc. Catheter devices and methods for their use in the treatment of calcified vascular occlusions
AU5101699A (en) * 1998-07-15 2000-02-07 Corazon Technologies, Inc. Methods and devices for reducing the mineral content of vascular calcified lesions
US6527979B2 (en) * 1999-08-27 2003-03-04 Corazon Technologies, Inc. Catheter systems and methods for their use in the treatment of calcified vascular occlusions
CA2403533C (en) * 2000-03-20 2014-12-30 Corazon Technologies, Inc. Methods and systems for enhancing fluid flow through an obstructed vascular site

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1914366A1 (de) * 1969-03-21 1970-10-01 Bayer Ag Arzneimittel auf Basis neuer,heterocyclischer Verbindungen
CH541576A (de) * 1970-11-03 1973-09-15 Ciba Geigy Ag Verfahren zur Herstellung thiaheterocyclischer Verbindungen
DE2219601A1 (de) 1971-04-27 1972-11-16 Astra Läkemedel AB, Södertälje (Schweden) beta-Lactame und Verfahren zu deren Herstellung
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
US4012383A (en) * 1975-01-02 1977-03-15 Bristol-Myers Company Δ2,3 -1,4-morpholine-2-carboxylic acids and derivatives thereof useful in preparation of antibacteria agents
US4011216A (en) * 1975-04-11 1977-03-08 Bristol-Myers Company Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents

Also Published As

Publication number Publication date
DE2633193A1 (de) 1977-02-10
CA1108136A (en) 1981-09-01
US4118566A (en) 1978-10-03
US4065622A (en) 1977-12-27
US4068066A (en) 1978-01-10
JPS5214798A (en) 1977-02-03
FR2318637A1 (fr) 1977-02-18
FR2392027A1 (fr) 1978-12-22
FR2318637B1 (enExample) 1979-03-02
US4013648A (en) 1977-03-22
CA1095908A (en) 1981-02-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee