GB1534216A - Production of live mumps virus and vaccine therefrom - Google Patents

Production of live mumps virus and vaccine therefrom

Info

Publication number
GB1534216A
GB1534216A GB28853/77A GB2885377A GB1534216A GB 1534216 A GB1534216 A GB 1534216A GB 28853/77 A GB28853/77 A GB 28853/77A GB 2885377 A GB2885377 A GB 2885377A GB 1534216 A GB1534216 A GB 1534216A
Authority
GB
United Kingdom
Prior art keywords
virus
vaccine
mumps
cell culture
mumps virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28853/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEDICINSKA AKADEMIA
Original Assignee
MEDICINSKA AKADEMIA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDICINSKA AKADEMIA filed Critical MEDICINSKA AKADEMIA
Priority to GB28853/77A priority Critical patent/GB1534216A/en
Publication of GB1534216A publication Critical patent/GB1534216A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/165—Mumps or measles virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1534216 Mumps vaccine MEDICINSKA AKADAMIA 8 July 1977 28853/77 Heading A5B [Also in Division C6] Mumps vaccine containing attenuated live mumps virus is produced by attenuating Sofia 6 strain of mumps virus by serial passage on a cell culture of cells from the kidneys of newborn guinea pigs (suitably 12 to 25 passages), and then multiplying the attenuated virus by allowing it to replicate on a cell culture of kidney cells of newborn guinea pigs, the culture being infected when it is three to five days old, then collecting the virus, e.g. 2, 4 or 6 days after inoculation of the cell culture, and using it to form a vaccine. The collected virus may be lyophilised, optionally after addition of a stabiliser such as sucrose, human albumin, phosphate and/or gelatin.
GB28853/77A 1977-07-08 1977-07-08 Production of live mumps virus and vaccine therefrom Expired GB1534216A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB28853/77A GB1534216A (en) 1977-07-08 1977-07-08 Production of live mumps virus and vaccine therefrom

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28853/77A GB1534216A (en) 1977-07-08 1977-07-08 Production of live mumps virus and vaccine therefrom

Publications (1)

Publication Number Publication Date
GB1534216A true GB1534216A (en) 1978-11-29

Family

ID=10282220

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28853/77A Expired GB1534216A (en) 1977-07-08 1977-07-08 Production of live mumps virus and vaccine therefrom

Country Status (1)

Country Link
GB (1) GB1534216A (en)

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee