GB1515909A - Method and apparatus for discriminating against extraneous particles in optical testing - Google Patents

Method and apparatus for discriminating against extraneous particles in optical testing

Info

Publication number
GB1515909A
GB1515909A GB53096/75A GB5309675A GB1515909A GB 1515909 A GB1515909 A GB 1515909A GB 53096/75 A GB53096/75 A GB 53096/75A GB 5309675 A GB5309675 A GB 5309675A GB 1515909 A GB1515909 A GB 1515909A
Authority
GB
United Kingdom
Prior art keywords
light
solution
interference signals
output signal
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53096/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Travenol Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/600,593 external-priority patent/US3967901A/en
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Priority to GB27078A priority Critical patent/GB1515910A/en
Publication of GB1515909A publication Critical patent/GB1515909A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Abstract

A chamber (15) for accommodating a test tube (24) holding the solution to be tested is located in a light-tight housing (12). A laser (13) is arranged such that the laser beam (14) can penetrate into the solution through an opening (28, 29). Situated as a light trap opposite the said opening is a recess (31) which is lined with light-absorbing material. Located at the external end of a light-passing channel (32) extending at approximately 45 DEG relative to the direction of the laser beam is a photodetector (36) for receiving the scattered light emanating from the solution. A NOT element is used to negate the output signal of the photodetector and to add to the negated signal by means of a circuit a constant signal of the same polarity as the interference signals but having a value exceeding the amplitude of the interference signals. Furthermore, a comparator and an electronic switch are provided for eliminating the negated interference signals. A filter element for smoothing the output signal is connected at the output of the electronic switch. The smooth output signal is fed to a digital display via an amplifier. <IMAGE>
GB53096/75A 1975-01-29 1975-12-30 Method and apparatus for discriminating against extraneous particles in optical testing Expired GB1515909A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB27078A GB1515910A (en) 1975-01-29 1975-12-30 Nephelometer and method of using same

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54506975A 1975-01-29 1975-01-29
US54506675A 1975-01-29 1975-01-29
US60078775A 1975-07-31 1975-07-31
US05/600,593 US3967901A (en) 1975-01-29 1975-07-31 Nephelometer having means semiautomatically cancelling components from scattering by particles smaller or larger than those of interest

Publications (1)

Publication Number Publication Date
GB1515909A true GB1515909A (en) 1978-06-28

Family

ID=27504713

Family Applications (1)

Application Number Title Priority Date Filing Date
GB53096/75A Expired GB1515909A (en) 1975-01-29 1975-12-30 Method and apparatus for discriminating against extraneous particles in optical testing

Country Status (15)

Country Link
JP (1) JPS562903B2 (en)
AU (1) AU503832B2 (en)
BE (1) BE837847A (en)
CH (1) CH613043A5 (en)
DE (1) DE2556677A1 (en)
DK (1) DK23576A (en)
ES (1) ES444659A1 (en)
FR (2) FR2307262A1 (en)
GB (1) GB1515909A (en)
IL (2) IL48531A (en)
IT (1) IT1054027B (en)
MX (1) MX143271A (en)
NL (1) NL7600084A (en)
NO (1) NO145896C (en)
SE (1) SE428728B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160914A (en) * 1977-12-16 1979-07-10 Monitek, Inc. Apparatus for measuring of particulate scattering in fluids
US4198161A (en) * 1978-02-27 1980-04-15 Hach Chemical Company Low turbidity nephelometer
JPS5565549U (en) * 1978-10-31 1980-05-06
JPS56137140A (en) * 1980-03-27 1981-10-26 Wako Pure Chem Ind Ltd Optical measuring method of blood coagulation
JPS56168148A (en) * 1980-05-29 1981-12-24 Joko:Kk Automatic starting method of immunity nephelometric device
JPS5861447A (en) * 1981-10-08 1983-04-12 Japan Spectroscopic Co Laser type quantitatively determining apparatus of reaction product of antigen and antibody
DE3706502A1 (en) * 1987-02-27 1988-09-08 Krupp Polysius Ag Device for determining the grain-size distribution of powdered material

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1802269C3 (en) * 1968-10-10 1979-09-27 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Method of measuring the concentration and / or size of particulate matter
US3669542A (en) * 1969-10-09 1972-06-13 Coulter Electronics Liquid borne particle sensor
US3670150A (en) * 1970-05-04 1972-06-13 Coulter Electronics Dynamic range splitter for an analyzer of particle-produced pulses
US3713743A (en) * 1970-11-25 1973-01-30 Agricultural Control Syst Forward scatter optical turbidimeter apparatus
CH549796A (en) * 1971-03-29 1974-05-31 Sigrist Willy METHOD FOR MEASURING SUBSTANCES SUSPENDED IN A LIQUID AND EQUIPMENT FOR CARRYING OUT THE METHOD.
US3772604A (en) * 1972-05-12 1973-11-13 Coulter Electronics Non-rectifying clamps
US3819269A (en) * 1973-01-26 1974-06-25 Miles Lab Apparatus for particle size analysis

Also Published As

Publication number Publication date
AU503832B2 (en) 1979-09-20
CH613043A5 (en) 1979-08-31
FR2307262A1 (en) 1976-11-05
DE2556677A1 (en) 1976-08-05
NO145896B (en) 1982-03-08
IL55909A0 (en) 1979-01-31
JPS562903B2 (en) 1981-01-22
SE428728B (en) 1983-07-18
IL48531A (en) 1979-09-30
FR2307311A1 (en) 1976-11-05
IT1054027B (en) 1981-11-10
NO760267L (en) 1976-07-30
FR2307262B1 (en) 1981-10-09
DK23576A (en) 1976-07-30
JPS5190883A (en) 1976-08-09
FR2307311B1 (en) 1981-08-21
AU8701375A (en) 1977-06-02
NO145896C (en) 1982-06-16
NL7600084A (en) 1976-08-02
BE837847A (en) 1976-05-14
ES444659A1 (en) 1978-02-16
MX143271A (en) 1981-04-13
IL48531A0 (en) 1976-01-30
SE7600908L (en) 1976-10-21

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19951229