GB1514748A - Pharmaceutically active piperidine derivatives and preparation thereof - Google Patents
Pharmaceutically active piperidine derivatives and preparation thereofInfo
- Publication number
- GB1514748A GB1514748A GB40030/75A GB4003075A GB1514748A GB 1514748 A GB1514748 A GB 1514748A GB 40030/75 A GB40030/75 A GB 40030/75A GB 4003075 A GB4003075 A GB 4003075A GB 1514748 A GB1514748 A GB 1514748A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperidine
- formula
- ethyl
- pyridine
- piperazinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003053 piperidines Chemical class 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004193 piperazinyl group Chemical group 0.000 abstract 2
- AVJKDKWRVSSJPK-UHFFFAOYSA-N 1-(4-fluorophenyl)piperazine Chemical compound C1=CC(F)=CC=C1N1CCNCC1 AVJKDKWRVSSJPK-UHFFFAOYSA-N 0.000 abstract 1
- WGCYRFWNGRMRJA-UHFFFAOYSA-N 1-ethylpiperazine Chemical group CCN1CCNCC1 WGCYRFWNGRMRJA-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical compound C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 229910052703 rhodium Inorganic materials 0.000 abstract 1
- 239000010948 rhodium Substances 0.000 abstract 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7432805A FR2285883A1 (fr) | 1974-09-30 | 1974-09-30 | Nouveaux composes chimiques a activite bronchospasmolytique et antitussive, et procede pour leur obtention |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1514748A true GB1514748A (en) | 1978-06-21 |
Family
ID=9143561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40030/75A Expired GB1514748A (en) | 1974-09-30 | 1975-09-30 | Pharmaceutically active piperidine derivatives and preparation thereof |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4029790A (enExample) |
| JP (1) | JPS5176281A (enExample) |
| DE (1) | DE2541932A1 (enExample) |
| FR (1) | FR2285883A1 (enExample) |
| GB (1) | GB1514748A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024072930A1 (en) * | 2022-09-30 | 2024-04-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dopamine d3/d2 receptor partial agonists for the treatment of neuropsychiatric disorders |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179563A (en) * | 1978-05-19 | 1979-12-18 | Warner-Lambert Company | 3-Aryloxy-substituted-aminopyridines and methods for their production |
| US4367335A (en) * | 1981-08-03 | 1983-01-04 | Mead Johnson & Company | Thiazolidinylalkylene piperazine derivatives |
| JP2008545010A (ja) * | 2005-06-30 | 2008-12-11 | プロシディオン・リミテッド | Gタンパク質共役受容体アゴニスト |
| EP2545046A4 (en) * | 2010-03-11 | 2015-03-25 | Sumitomo Dainippon Pharma Co Ltd | CYCLIC N-ACYL-AMINE DERIVATIVE OR PHARMACEUTICALLY ALLOWED SALT THEREOF |
| JP5715605B2 (ja) * | 2011-09-14 | 2015-05-07 | 大日本住友製薬株式会社 | N−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL132357C (enExample) * | 1966-09-03 | |||
| US3753985A (en) * | 1970-12-28 | 1973-08-21 | Miles Lab | 3-amino-flavanones |
-
1974
- 1974-09-30 FR FR7432805A patent/FR2285883A1/fr active Granted
-
1975
- 1975-09-19 DE DE19752541932 patent/DE2541932A1/de not_active Withdrawn
- 1975-09-26 US US05/617,141 patent/US4029790A/en not_active Expired - Lifetime
- 1975-09-29 JP JP50118226A patent/JPS5176281A/ja active Pending
- 1975-09-30 GB GB40030/75A patent/GB1514748A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024072930A1 (en) * | 2022-09-30 | 2024-04-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dopamine d3/d2 receptor partial agonists for the treatment of neuropsychiatric disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2285883B1 (enExample) | 1978-07-21 |
| JPS5176281A (enExample) | 1976-07-01 |
| FR2285883A1 (fr) | 1976-04-23 |
| US4029790A (en) | 1977-06-14 |
| DE2541932A1 (de) | 1976-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |