GB1501074A - Derivatives of salicylic acid suitable for use in therapeutics - Google Patents
Derivatives of salicylic acid suitable for use in therapeuticsInfo
- Publication number
- GB1501074A GB1501074A GB1190876A GB1190876A GB1501074A GB 1501074 A GB1501074 A GB 1501074A GB 1190876 A GB1190876 A GB 1190876A GB 1190876 A GB1190876 A GB 1190876A GB 1501074 A GB1501074 A GB 1501074A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nitrogen atom
- carbon atoms
- tertiary nitrogen
- hydrocarbon group
- aliphatic hydrocarbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1501074 Salicylic acid derivatives SOC D'ETUDES ET APPLICATIONS CHIMIQUES (SEAC) 24 March 1976 [24 March 1975] 11908/76 Heading C2C Novel compounds of formula in which X has one of the formulµ -OR 1 and -NHR 2 in which R 1 is a hydrogen atom or a straight or branched chain aliphatic hydrocarbon group having 1 to 7 carbon atoms, an aliphatic hydrocarbon group having 1 to 7 carbon atoms linked to a tertiary nitrogen atom or linked to a saturated heterocycle having 5 or 6 ring atoms including a tertiary nitrogen atom and which may also include an oxygen atom, and R 2 is a hydrogen atom or a straight or branched chain aliphatic hydrocarbon group having 1 to 6 carbon atoms, an aliphatic hydrocarbon group having 1 to 6 carbon atoms linked to a tertiary nitrogen atom or linked to a saturated heterocycle having 5 or 6 ring atoms including a tertiary nitrogen atom and which may also include an additional nitrogen atom or an oxygen atom, said tertiary nitrogen atom being separated from the amide nitrogen by at least two carbon atoms, together with (a) salts of said acid with mineral and organic bases and (b) salts of said esters and amides containing a tertiary nitrogen atom with mineral and organic acids, are prepared by esterifying salicylic acid with 2-(4-chlorophenoxy)isobutyric acid, or a functional derivative thereof, followed, if required, by esterifying or amidating the carboxylic functional of the resulting derivative. Pharmaceutical compositions for treating inflammatory conditions and complaints due to blood clotting comprise a compound of the invention together with a pharmaceutical carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7509195A FR2305188A1 (en) | 1975-03-24 | 1975-03-24 | NEW DERIVATIVES OF SALICYLIC ACID, USED IN THERAPEUTICS |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1501074A true GB1501074A (en) | 1978-02-15 |
Family
ID=9153004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1190876A Expired GB1501074A (en) | 1975-03-24 | 1976-03-24 | Derivatives of salicylic acid suitable for use in therapeutics |
Country Status (9)
Country | Link |
---|---|
BE (1) | BE839959A (en) |
CH (1) | CH610876A5 (en) |
DE (1) | DE2612321A1 (en) |
ES (1) | ES446295A1 (en) |
FR (1) | FR2305188A1 (en) |
GB (1) | GB1501074A (en) |
LU (1) | LU74624A1 (en) |
NL (1) | NL7603068A (en) |
PT (1) | PT64940B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2730174C2 (en) * | 1977-07-04 | 1981-12-10 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Aminobenzoic acid derivatives and medicaments containing such aminobenzoic acid derivatives |
US4615330A (en) * | 1983-09-05 | 1986-10-07 | Olympus Optical Co., Ltd. | Noise suppressor for electronic endoscope |
-
1975
- 1975-03-24 FR FR7509195A patent/FR2305188A1/en active Granted
-
1976
- 1976-03-23 LU LU74624A patent/LU74624A1/xx unknown
- 1976-03-23 ES ES446295A patent/ES446295A1/en not_active Expired
- 1976-03-23 DE DE19762612321 patent/DE2612321A1/en not_active Withdrawn
- 1976-03-24 CH CH365976A patent/CH610876A5/en not_active IP Right Cessation
- 1976-03-24 GB GB1190876A patent/GB1501074A/en not_active Expired
- 1976-03-24 BE BE165500A patent/BE839959A/en unknown
- 1976-03-24 NL NL7603068A patent/NL7603068A/en not_active Application Discontinuation
- 1976-03-24 PT PT6494076A patent/PT64940B/en unknown
Also Published As
Publication number | Publication date |
---|---|
LU74624A1 (en) | 1976-09-01 |
PT64940A (en) | 1976-04-01 |
NL7603068A (en) | 1976-09-28 |
DE2612321A1 (en) | 1976-10-07 |
PT64940B (en) | 1977-08-25 |
ES446295A1 (en) | 1977-12-01 |
FR2305188B1 (en) | 1979-03-16 |
CH610876A5 (en) | 1979-05-15 |
BE839959A (en) | 1976-07-16 |
FR2305188A1 (en) | 1976-10-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |