CH610876A5 - Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid - Google Patents

Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid

Info

Publication number
CH610876A5
CH610876A5 CH365976A CH365976A CH610876A5 CH 610876 A5 CH610876 A5 CH 610876A5 CH 365976 A CH365976 A CH 365976A CH 365976 A CH365976 A CH 365976A CH 610876 A5 CH610876 A5 CH 610876A5
Authority
CH
Switzerland
Prior art keywords
acid
chlorophenoxyisobutyrylsalicylic
preparation
amides
esters
Prior art date
Application number
CH365976A
Inventor
Claude Dufour
Original Assignee
Claude Dufour
Seac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Claude Dufour, Seac filed Critical Claude Dufour
Publication of CH610876A5 publication Critical patent/CH610876A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

4-Chlorophenoxyisobutyrylsalicylic acid of formula <IMAGE> is prepared by reaction of salicylic acid with 4-chlorophenoxyisobutyryl chloride. The compound of formula I as well as its salts, esters or amides, especially its salts with inorganic and organic bases, its esters, in particular with aminoalcohols, and its amides with mono- or polyamines, can be used for the treatment of hypercholesterolemic states and of platelet aggregation phenomena.
CH365976A 1975-03-24 1976-03-24 Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid CH610876A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7509195A FR2305188A1 (en) 1975-03-24 1975-03-24 NEW DERIVATIVES OF SALICYLIC ACID, USED IN THERAPEUTICS

Publications (1)

Publication Number Publication Date
CH610876A5 true CH610876A5 (en) 1979-05-15

Family

ID=9153004

Family Applications (1)

Application Number Title Priority Date Filing Date
CH365976A CH610876A5 (en) 1975-03-24 1976-03-24 Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid

Country Status (9)

Country Link
BE (1) BE839959A (en)
CH (1) CH610876A5 (en)
DE (1) DE2612321A1 (en)
ES (1) ES446295A1 (en)
FR (1) FR2305188A1 (en)
GB (1) GB1501074A (en)
LU (1) LU74624A1 (en)
NL (1) NL7603068A (en)
PT (1) PT64940B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730174C2 (en) * 1977-07-04 1981-12-10 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Aminobenzoic acid derivatives and medicaments containing such aminobenzoic acid derivatives
US4615330A (en) * 1983-09-05 1986-10-07 Olympus Optical Co., Ltd. Noise suppressor for electronic endoscope

Also Published As

Publication number Publication date
LU74624A1 (en) 1976-09-01
DE2612321A1 (en) 1976-10-07
FR2305188B1 (en) 1979-03-16
GB1501074A (en) 1978-02-15
ES446295A1 (en) 1977-12-01
FR2305188A1 (en) 1976-10-22
BE839959A (en) 1976-07-16
NL7603068A (en) 1976-09-28
PT64940B (en) 1977-08-25
PT64940A (en) 1976-04-01

Similar Documents

Publication Publication Date Title
SE7408388L (en)
SE7611047L (en) PROCEDURE FOR PREPARING ANTIBACTERIAL SUBJECT
YU159475A (en) Process for obtaining new benzimidazoline derivatives
GB1323502A (en) Erythromycin derivatives
CH610876A5 (en) Process for the preparation of 4-chlorophenoxyisobutyrylsalicylic acid
SE8302193L (en) N- (1-SUBSTITUTED-3-PYRROLIDINYL) -BENZAMIDES AND THIOBENSAMIDES
ES417396A1 (en) A procedure for the production of a pharmaceutical composition. (Machine-translation by Google Translate, not legally binding)
ES444508A1 (en) Process for the preparation of phloroglucinol
ES450299A1 (en) Amides of pyrrolidinoethylamine which can be used in treatment of coughs
JPS5278753A (en) Desulfurization of exhaust gas
GB940488A (en) Penicillins
GB1531459A (en) Preparation of solutions of a basic aluminium compound and their use in water treatment
CH612907A5 (en) Process for the preparation of a new 1-aryloxy-4-amino-2-butanol
GB1473484A (en) Nitrogen-containing polycyclic compounds and a process for the preparation thereof
ES369259A1 (en) Procedure for the preparation of N- (alpha-naftoxy-isobutiril) - 6-aminohexanic acid. (Machine-translation by Google Translate, not legally binding)
GB896040A (en) Process for the manufacture of thiophenedisulphochlorides
JPS51122011A (en) Process for preparation of organic silver carboxylate
GB920177A (en) Penicillins
ES409555A1 (en) A procedure for the obtaining of new derivatives of cefalosporine. (Machine-translation by Google Translate, not legally binding)
IE37489B1 (en) Benzylamine analgesics
ES382705A1 (en) Procedure for the preparation of substitute azabiciclooctanes. (Machine-translation by Google Translate, not legally binding)
ES320141A1 (en) A procedure for the preparation of penicillins. (Machine-translation by Google Translate, not legally binding)
ES384599A1 (en) Procedure for the preparation of new basic pirrol derivatives. (Machine-translation by Google Translate, not legally binding)
ES8104172A1 (en) Basically substituted phenols, process for their preparation, pharmaceutical preparations containing these compounds and their use.
ES380903A1 (en) A method of obtaining two salts, biologically active, from 2-propylvaleric acid. (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
PL Patent ceased