GB1485450A - Process for the preparation of a kanamycin derivative - Google Patents
Process for the preparation of a kanamycin derivativeInfo
- Publication number
- GB1485450A GB1485450A GB48641/74A GB4864174A GB1485450A GB 1485450 A GB1485450 A GB 1485450A GB 48641/74 A GB48641/74 A GB 48641/74A GB 4864174 A GB4864174 A GB 4864174A GB 1485450 A GB1485450 A GB 1485450A
- Authority
- GB
- United Kingdom
- Prior art keywords
- kanamycin
- compound
- preparation
- derivative
- kanamycin derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical class O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- ULKOBRDRCYROKY-JTQLQIEISA-N (2s)-2-hydroxy-4-(phenylmethoxycarbonylamino)butanoic acid Chemical compound OC(=O)[C@@H](O)CCNC(=O)OCC1=CC=CC=C1 ULKOBRDRCYROKY-JTQLQIEISA-N 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- -1 N-hydroxy-5-norbornene-2,3-dicarboximide ester Chemical class 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 229960000318 kanamycin Drugs 0.000 abstract 1
- 229930182823 kanamycin A Natural products 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41558973A | 1973-11-14 | 1973-11-14 | |
| US47278074A | 1974-05-23 | 1974-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1485450A true GB1485450A (en) | 1977-09-14 |
Family
ID=27023027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB48641/74A Expired GB1485450A (en) | 1973-11-14 | 1974-11-11 | Process for the preparation of a kanamycin derivative |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS572719B2 (enrdf_load_stackoverflow) |
| CA (1) | CA1030961A (enrdf_load_stackoverflow) |
| CH (1) | CH617441A5 (enrdf_load_stackoverflow) |
| DK (1) | DK142991C (enrdf_load_stackoverflow) |
| ES (1) | ES431912A1 (enrdf_load_stackoverflow) |
| FI (1) | FI60217C (enrdf_load_stackoverflow) |
| GB (1) | GB1485450A (enrdf_load_stackoverflow) |
| NL (1) | NL157910B (enrdf_load_stackoverflow) |
| NO (1) | NO142785C (enrdf_load_stackoverflow) |
| SE (2) | SE419649B (enrdf_load_stackoverflow) |
| YU (1) | YU39655B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0317970A3 (en) * | 1987-11-27 | 1991-08-28 | GIST BROCADES ITALY S.p.A. | A process for the synthesis of amikacin |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1139844B (it) * | 1981-11-25 | 1986-09-24 | Corvi Mora Paolo | Processo per la preparazione di amikacina |
-
1974
- 1974-11-11 FI FI3270/74A patent/FI60217C/fi active
- 1974-11-11 NL NL7414668.A patent/NL157910B/xx not_active IP Right Cessation
- 1974-11-11 GB GB48641/74A patent/GB1485450A/en not_active Expired
- 1974-11-12 NO NO744064A patent/NO142785C/no unknown
- 1974-11-13 ES ES431912A patent/ES431912A1/es not_active Expired
- 1974-11-13 CA CA213,628A patent/CA1030961A/en not_active Expired
- 1974-11-13 DK DK591674A patent/DK142991C/da active
- 1974-11-13 YU YU3017/74A patent/YU39655B/xx unknown
- 1974-11-14 JP JP13057074A patent/JPS572719B2/ja not_active Expired
- 1974-11-14 SE SE7414332A patent/SE419649B/xx not_active IP Right Cessation
- 1974-11-14 CH CH1521274A patent/CH617441A5/de not_active IP Right Cessation
-
1977
- 1977-05-23 SE SE7706005A patent/SE441272B/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0317970A3 (en) * | 1987-11-27 | 1991-08-28 | GIST BROCADES ITALY S.p.A. | A process for the synthesis of amikacin |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS572719B2 (enrdf_load_stackoverflow) | 1982-01-18 |
| SE7414332L (enrdf_load_stackoverflow) | 1975-05-15 |
| FI327074A7 (enrdf_load_stackoverflow) | 1975-05-15 |
| YU39655B (en) | 1985-03-20 |
| FI60217B (fi) | 1981-08-31 |
| YU301774A (en) | 1982-05-31 |
| JPS5077345A (enrdf_load_stackoverflow) | 1975-06-24 |
| SE419649B (sv) | 1981-08-17 |
| SE441272B (sv) | 1985-09-23 |
| NO142785B (no) | 1980-07-07 |
| NO142785C (no) | 1980-10-15 |
| FI60217C (fi) | 1981-12-10 |
| NO744064L (enrdf_load_stackoverflow) | 1975-06-09 |
| NL7414668A (nl) | 1975-05-16 |
| DK142991C (da) | 1981-09-07 |
| CA1030961A (en) | 1978-05-09 |
| DK591674A (enrdf_load_stackoverflow) | 1975-07-14 |
| DK142991B (da) | 1981-03-09 |
| CH617441A5 (en) | 1980-05-30 |
| NL157910B (nl) | 1978-09-15 |
| ES431912A1 (es) | 1977-01-01 |
| SE7706005L (sv) | 1977-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19941110 |