GB1481222A - Aminodibenzo(b,d)pyrans - Google Patents
Aminodibenzo(b,d)pyransInfo
- Publication number
- GB1481222A GB1481222A GB34135/74A GB3413574A GB1481222A GB 1481222 A GB1481222 A GB 1481222A GB 34135/74 A GB34135/74 A GB 34135/74A GB 3413574 A GB3413574 A GB 3413574A GB 1481222 A GB1481222 A GB 1481222A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- tetrahydro
- hydroxy
- alkyl
- dimethylheptyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004880 oxines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000006559 (C1-C3) alkylamino group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- OBHKONRNYCDRKM-UHFFFAOYSA-N 4-chloro-2-phenylquinazoline Chemical compound N=1C2=CC=CC=C2C(Cl)=NC=1C1=CC=CC=C1 OBHKONRNYCDRKM-UHFFFAOYSA-N 0.000 abstract 1
- 229930188104 Alkylresorcinol Natural products 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- JEDZLBFUGJTJGQ-UHFFFAOYSA-N [Na].COCCO[AlH]OCCOC Chemical compound [Na].COCCO[AlH]OCCOC JEDZLBFUGJTJGQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910000102 alkali metal hydride Inorganic materials 0.000 abstract 1
- 150000008046 alkali metal hydrides Chemical class 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000049 anti-anxiety effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/489,742 US3930365A (en) | 1974-07-18 | 1974-07-18 | Fuel control system for gas turbine engine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US385367A US3886184A (en) | 1973-08-03 | 1973-08-03 | Aminodibenzo(b,d)pyrans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1481222A true GB1481222A (en) | 1977-07-27 |
Family
ID=23521121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB34135/74A Expired GB1481222A (en) | 1973-08-03 | 1974-08-02 | Aminodibenzo(b,d)pyrans |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3886184A (enExample) |
| JP (1) | JPS6011037B2 (enExample) |
| AR (2) | AR202030A1 (enExample) |
| AT (1) | AT336608B (enExample) |
| BE (1) | BE818418A (enExample) |
| BG (1) | BG22829A3 (enExample) |
| CA (1) | CA1023754A (enExample) |
| CH (1) | CH605893A5 (enExample) |
| DD (1) | DD112999A5 (enExample) |
| DE (1) | DE2437135C2 (enExample) |
| DK (1) | DK413074A (enExample) |
| ES (1) | ES428915A1 (enExample) |
| FR (1) | FR2240003B1 (enExample) |
| GB (1) | GB1481222A (enExample) |
| HU (1) | HU168622B (enExample) |
| IE (1) | IE39555B1 (enExample) |
| IL (1) | IL45130A (enExample) |
| NL (1) | NL7410351A (enExample) |
| PH (1) | PH10463A (enExample) |
| PL (1) | PL99837B1 (enExample) |
| SE (1) | SE7409999L (enExample) |
| SU (1) | SU555855A3 (enExample) |
| ZA (1) | ZA744095B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235913A (en) * | 1977-06-07 | 1980-11-25 | Pfizer Inc. | 9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans |
| US4195025A (en) * | 1978-02-17 | 1980-03-25 | Eli Lilly And Company | 9-Amino-dibenzopyrans |
| US4454144A (en) * | 1982-06-21 | 1984-06-12 | Pfizer Inc. | Substituted dibenzo[b,d]pyran analgesics |
| US5264373A (en) * | 1987-02-17 | 1993-11-23 | Abbott Laboratories | Fluorescence polarization immunoassay for tetrahydrocannabinoids |
| US4931221A (en) * | 1988-12-30 | 1990-06-05 | Ppg Industries, Inc. | Photochromic spiropyran compounds |
| US5180736A (en) * | 1989-03-23 | 1993-01-19 | Warner-Lambert Company | Polycyclic amines useful as cerebrovascular agents |
| US5498419A (en) * | 1994-06-03 | 1996-03-12 | Pars; Harry G. | Fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol, 4-(diethyl-amino) butyric |
| US20010009965A1 (en) * | 1998-05-04 | 2001-07-26 | Alexandros Makriyannis | Novel analgesic and immunomodulatory cannabinoids |
| DE69920683T2 (de) * | 1998-05-04 | 2005-04-07 | The University Of Connecticut, Farmington | Selektiv auf den CB2-Rezeptor wirkende Cannabinoide |
| US7589220B2 (en) * | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
| US7897598B2 (en) * | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
| US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
| US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
| US7119108B1 (en) | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
| US7741365B2 (en) * | 1999-10-18 | 2010-06-22 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
| US6943266B1 (en) | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
| US7393842B2 (en) * | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
| DE60033834T2 (de) | 1999-10-18 | 2007-11-15 | The University Of Connecticut, Farmington | Für periphäre cannabinoid-rezeptoren selektive liganden |
| US8084467B2 (en) * | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
| US6900236B1 (en) * | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
| WO2002058636A2 (en) * | 2001-01-26 | 2002-08-01 | University Of Connecticut | Novel cannabimimetic ligands |
| EP1363632B1 (en) | 2001-01-29 | 2010-08-25 | The University of Connecticut | Receptor selective cannabimimetic aminoalkylindoles |
| EP1414775B1 (en) * | 2001-07-13 | 2012-12-19 | The University of Connecticut | Bicyclic cannabinoid |
| US7666867B2 (en) * | 2001-10-26 | 2010-02-23 | University Of Connecticut | Heteroindanes: a new class of potent cannabimimetic ligands |
| JP2006511460A (ja) | 2002-08-23 | 2006-04-06 | ユニバーシティ オブ コネチカット | 治療適応を持つケトカンナビノイド |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3656906A (en) * | 1970-04-13 | 1972-04-18 | Little Inc A | Method for detecting and quantitating the presence of cannabinoids and analogs thereof in biological materials and resulting products |
-
1973
- 1973-08-03 US US385367A patent/US3886184A/en not_active Expired - Lifetime
-
1974
- 1974-06-24 IE IE1327/74A patent/IE39555B1/xx unknown
- 1974-06-25 ZA ZA00744095A patent/ZA744095B/xx unknown
- 1974-06-27 IL IL45130A patent/IL45130A/en unknown
- 1974-06-28 CA CA203,730A patent/CA1023754A/en not_active Expired
- 1974-07-05 PH PH16017A patent/PH10463A/en unknown
- 1974-07-15 AR AR254694A patent/AR202030A1/es active
- 1974-07-30 PL PL1974173119A patent/PL99837B1/pl unknown
- 1974-08-01 NL NL7410351A patent/NL7410351A/xx not_active Application Discontinuation
- 1974-08-01 AT AT633274A patent/AT336608B/de not_active IP Right Cessation
- 1974-08-01 DE DE2437135A patent/DE2437135C2/de not_active Expired
- 1974-08-02 SE SE7409999A patent/SE7409999L/xx unknown
- 1974-08-02 ES ES428915A patent/ES428915A1/es not_active Expired
- 1974-08-02 CH CH1066674A patent/CH605893A5/xx not_active IP Right Cessation
- 1974-08-02 BE BE1006106A patent/BE818418A/xx not_active IP Right Cessation
- 1974-08-02 HU HUEI558A patent/HU168622B/hu unknown
- 1974-08-02 DD DD180291A patent/DD112999A5/xx unknown
- 1974-08-02 GB GB34135/74A patent/GB1481222A/en not_active Expired
- 1974-08-02 FR FR7427014A patent/FR2240003B1/fr not_active Expired
- 1974-08-02 DK DK413074A patent/DK413074A/da unknown
- 1974-08-02 SU SU2056163A patent/SU555855A3/ru active
- 1974-08-03 JP JP49089398A patent/JPS6011037B2/ja not_active Expired
- 1974-08-03 BG BG027424A patent/BG22829A3/xx unknown
-
1975
- 1975-04-21 AR AR258443A patent/AR202509A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| BG22829A3 (bg) | 1977-04-20 |
| HU168622B (enExample) | 1976-06-28 |
| ATA633274A (de) | 1976-09-15 |
| BE818418A (fr) | 1975-02-03 |
| AT336608B (de) | 1977-05-10 |
| FR2240003B1 (enExample) | 1978-07-21 |
| AR202509A1 (es) | 1975-06-13 |
| IE39555B1 (en) | 1978-11-08 |
| FR2240003A1 (enExample) | 1975-03-07 |
| AR202030A1 (es) | 1975-05-09 |
| IE39555L (en) | 1975-02-03 |
| IL45130A0 (en) | 1974-09-10 |
| DK413074A (enExample) | 1975-04-01 |
| AU7105574A (en) | 1976-01-15 |
| DE2437135A1 (de) | 1975-02-13 |
| NL7410351A (nl) | 1975-02-05 |
| SU555855A3 (ru) | 1977-04-25 |
| PL99837B1 (pl) | 1978-08-31 |
| ES428915A1 (es) | 1976-08-16 |
| SE7409999L (enExample) | 1975-02-04 |
| JPS6011037B2 (ja) | 1985-03-22 |
| IL45130A (en) | 1977-10-31 |
| DE2437135C2 (de) | 1983-12-29 |
| DD112999A5 (enExample) | 1975-05-12 |
| ZA744095B (en) | 1976-02-25 |
| CH605893A5 (enExample) | 1978-10-13 |
| PH10463A (en) | 1977-04-25 |
| CA1023754A (en) | 1978-01-03 |
| JPS5041866A (enExample) | 1975-04-16 |
| US3886184A (en) | 1975-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 49R | Reference inserted (sect. 9/1949) | ||
| SP | Amendment (slips) printed | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |