GB1473601A - Antigenic modification of polypeptides - Google Patents

Antigenic modification of polypeptides

Info

Publication number
GB1473601A
GB1473601A GB2001874A GB2001874A GB1473601A GB 1473601 A GB1473601 A GB 1473601A GB 2001874 A GB2001874 A GB 2001874A GB 2001874 A GB2001874 A GB 2001874A GB 1473601 A GB1473601 A GB 1473601A
Authority
GB
United Kingdom
Prior art keywords
human
polypeptides
peptide
active
antigenic modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2001874A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University
Original Assignee
Ohio State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University filed Critical Ohio State University
Publication of GB1473601A publication Critical patent/GB1473601A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The composition has an active immunising action against reproduction in humans and mammals. It contains as active component a biologically determinant peptide of one of the protein-reproducing hormones follicle-stimulating hormone (FSH), luteinising hormone (LH), human placental lactogen (HPL), human prolactin or human chorionic gonadotropin (HCG). The peptide is modified to an artificial antigen in an immunochemically known way.
GB2001874A 1973-05-07 1974-05-07 Antigenic modification of polypeptides Expired GB1473601A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35789273A 1973-05-07 1973-05-07
US40682173A 1973-10-16 1973-10-16

Publications (1)

Publication Number Publication Date
GB1473601A true GB1473601A (en) 1977-05-18

Family

ID=26999834

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2001874A Expired GB1473601A (en) 1973-05-07 1974-05-07 Antigenic modification of polypeptides

Country Status (17)

Country Link
JP (1) JPS623128B2 (en)
AT (1) AT356263B (en)
AU (1) AU524925B2 (en)
CA (1) CA1057742A (en)
CH (1) CH622426A5 (en)
DD (1) DD113919A5 (en)
DE (1) DE2421943A1 (en)
FR (1) FR2228477B1 (en)
GB (1) GB1473601A (en)
HK (1) HK41280A (en)
IE (1) IE42002B1 (en)
IL (1) IL44779A (en)
MY (1) MY8100128A (en)
NL (1) NL7406098A (en)
NZ (1) NZ174192A (en)
PL (1) PL97318B1 (en)
SE (1) SE7406096L (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2842612A1 (en) * 1978-02-06 1979-08-09 Research Corp ANTIGEN FOR PREGNANCY AND PREGNANCY PREVENTION VACCINE
US4310455A (en) * 1979-04-17 1982-01-12 Research Corporation Antigen for early pregnancy test and contraceptive vaccine

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
CA1054937A (en) * 1975-01-28 1979-05-22 Gursaran P. Talwar Antipregnancy vaccine
FR2319379A1 (en) * 1975-07-29 1977-02-25 All India Inst Medical Scie Contraceptive vaccine for women - comprising a conjugate of tetanus anatoxin andhuman chlorionic gonadotrophin (3-sub-unit with no strong reaction with anti-LH serium)
JPS55160725A (en) * 1975-07-30 1980-12-13 Paashiyado Taruwaa Gaasaran Contraceptive vaccine and its manufacture
NZ182272A (en) * 1975-10-14 1985-03-20 Univ Ohio State Modified polypeptides for the immunological control of fertility,and pharmaceutical compositions
JPS5294416A (en) * 1976-01-24 1977-08-09 Paashiyado Taruwaa Gaasaran Vaccine for contraception and use of same
JPS5633907Y2 (en) * 1976-09-16 1981-08-11
US4096237A (en) * 1977-03-14 1978-06-20 Hoffmann-La Roche Inc. Immunoassay for β-endorphin
CA1239346A (en) * 1985-06-04 1988-07-19 Gursaran P. Talwar Birth control vaccine
FR2832066A1 (en) * 2001-11-14 2003-05-16 Agronomique Inst Nat Rech CONTRACEPTIVE VACCINE COMPOSITIONS COMPRISING A PEPTIDE OR A SET OF PEPTIDES ENCODED BY ALL OR PART OF EXON 1 OF AN FSH RECEPTOR

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA903671A (en) * 1972-06-27 J. Lewis Andrew Soluble cancer antigens coupled to foreign proteins
DE1467782A1 (en) * 1963-07-17 1968-12-12 Behringwerke Ag Process for the production of artificial antigens
US3317400A (en) * 1964-11-23 1967-05-02 Upjohn Co Enzymatic modification of bovine growth hormone by proteolytic streptomycete cell extracts
GB1393965A (en) * 1971-05-05 1975-05-14 Ortho Pharma Corp Vaccine and method for inducing infertility in a male animal

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2842612A1 (en) * 1978-02-06 1979-08-09 Research Corp ANTIGEN FOR PREGNANCY AND PREGNANCY PREVENTION VACCINE
US4234561A (en) * 1978-02-06 1980-11-18 Research Corporation Antigen for early pregnancy test and contraceptive vaccine
US4310455A (en) * 1979-04-17 1982-01-12 Research Corporation Antigen for early pregnancy test and contraceptive vaccine

Also Published As

Publication number Publication date
NL7406098A (en) 1974-11-11
DE2421943C2 (en) 1989-10-26
FR2228477B1 (en) 1977-07-01
AU524925B2 (en) 1982-10-14
HK41280A (en) 1980-08-15
JPS5069221A (en) 1975-06-10
SE7406096L (en) 1975-01-31
PL97318B1 (en) 1978-02-28
DE2421943A1 (en) 1974-11-28
IL44779A (en) 1977-10-31
CH622426A5 (en) 1981-04-15
IE42002B1 (en) 1980-05-21
AT356263B (en) 1980-04-25
IE42002L (en) 1974-11-07
MY8100128A (en) 1981-12-31
IL44779A0 (en) 1974-07-31
CA1057742A (en) 1979-07-03
NZ174192A (en) 1985-02-28
DD113919A5 (en) 1975-07-05
AU6869574A (en) 1975-11-13
ATA377074A (en) 1979-09-15
JPS623128B2 (en) 1987-01-23
FR2228477A1 (en) 1974-12-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee