GB1472746A - Cephalosporin compounds - Google Patents

Cephalosporin compounds

Info

Publication number
GB1472746A
GB1472746A GB3211173A GB3211173A GB1472746A GB 1472746 A GB1472746 A GB 1472746A GB 3211173 A GB3211173 A GB 3211173A GB 3211173 A GB3211173 A GB 3211173A GB 1472746 A GB1472746 A GB 1472746A
Authority
GB
United Kingdom
Prior art keywords
cephalexin
solvate
reaction
adca
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3211173A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Glaxo Laboratories Ltd
Original Assignee
Laboratoires Glaxo SA
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA, Glaxo Laboratories Ltd filed Critical Laboratoires Glaxo SA
Priority to GB3211173A priority Critical patent/GB1472746A/en
Priority to YU1862/74A priority patent/YU39525B/xx
Priority to US05/485,236 priority patent/US3957773A/en
Priority to AU70722/74A priority patent/AU488292B2/en
Priority to CA204,112A priority patent/CA1027555A/en
Priority to CH916574A priority patent/CH601315A5/xx
Priority to LU70467A priority patent/LU70467A1/xx
Priority to SE7408833A priority patent/SE428565B/xx
Priority to BE146232A priority patent/BE817266A/xx
Priority to FR7423251A priority patent/FR2235943B1/fr
Priority to ES427961A priority patent/ES427961A1/es
Priority to DK358874A priority patent/DK144915C/da
Priority to JP7590574A priority patent/JPS5318517B2/ja
Priority to DE2432485A priority patent/DE2432485C3/de
Priority to ZA00744314A priority patent/ZA744314B/xx
Priority to IE1419/74A priority patent/IE39590B1/xx
Priority to HUGA1163A priority patent/HU169318B/hu
Priority to PL1974172423A priority patent/PL91389B1/pl
Priority to NLAANVRAGE7409050,A priority patent/NL169478C/xx
Priority to AT552774A priority patent/AT341085B/de
Publication of GB1472746A publication Critical patent/GB1472746A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB3211173A 1973-07-05 1973-07-05 Cephalosporin compounds Expired GB1472746A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
GB3211173A GB1472746A (en) 1973-07-05 1973-07-05 Cephalosporin compounds
YU1862/74A YU39525B (en) 1973-07-05 1974-07-02 Process for the manufacture of the bis-dimethylformamide solvate of cephalexin
US05/485,236 US3957773A (en) 1973-07-05 1974-07-02 Process for preparing cephalosporin compounds from 7-adca
AU70722/74A AU488292B2 (en) 1973-07-05 1974-07-02 Improvements in or relating to cephalosporin compounds
CA204,112A CA1027555A (en) 1973-07-05 1974-07-04 Cephalosporin compounds
CH916574A CH601315A5 (instruction) 1973-07-05 1974-07-04
LU70467A LU70467A1 (instruction) 1973-07-05 1974-07-04
SE7408833A SE428565B (sv) 1973-07-05 1974-07-04 Forfarande for framstellning av cefalexin eller ett bisdimetylformamidsolvat av cefalexin
BE146232A BE817266A (fr) 1973-07-05 1974-07-04 Procede de preparation de cephalexine
FR7423251A FR2235943B1 (instruction) 1973-07-05 1974-07-04
ES427961A ES427961A1 (es) 1973-07-05 1974-07-04 Un procedimiento para la preparacion de un solvato de bis- dimetilformamida de cefalexina.
DK358874A DK144915C (da) 1973-07-05 1974-07-04 Fremgangsmaade til fremstilling af cephalexin eller et bis-dimetylformamidsolvat deraf
JP7590574A JPS5318517B2 (instruction) 1973-07-05 1974-07-04
DE2432485A DE2432485C3 (de) 1973-07-05 1974-07-04 Verfahren zur Herstellung von Cefalexin
ZA00744314A ZA744314B (en) 1973-07-05 1974-07-04 Improvements in or relating to cephalosporin compounds
IE1419/74A IE39590B1 (en) 1973-07-05 1974-07-04 Improvements in or relating to cephalosporin compounds
HUGA1163A HU169318B (instruction) 1973-07-05 1974-07-04
PL1974172423A PL91389B1 (instruction) 1973-07-05 1974-07-04
NLAANVRAGE7409050,A NL169478C (nl) 1973-07-05 1974-07-04 Werkwijze voor het bereiden van een cefalexineverbinding.
AT552774A AT341085B (de) 1973-07-05 1974-07-04 Verfahren zur herstellung eines bis-dimethylformamid-solvats von 7beta- (d-2-amino-2-phenylacetamido)-3-methylceph-3-em-4-carbonsaure (cephalexin)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3211173A GB1472746A (en) 1973-07-05 1973-07-05 Cephalosporin compounds

Publications (1)

Publication Number Publication Date
GB1472746A true GB1472746A (en) 1977-05-04

Family

ID=10333421

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3211173A Expired GB1472746A (en) 1973-07-05 1973-07-05 Cephalosporin compounds

Country Status (19)

Country Link
US (1) US3957773A (instruction)
JP (1) JPS5318517B2 (instruction)
AT (1) AT341085B (instruction)
BE (1) BE817266A (instruction)
CA (1) CA1027555A (instruction)
CH (1) CH601315A5 (instruction)
DE (1) DE2432485C3 (instruction)
DK (1) DK144915C (instruction)
ES (1) ES427961A1 (instruction)
FR (1) FR2235943B1 (instruction)
GB (1) GB1472746A (instruction)
HU (1) HU169318B (instruction)
IE (1) IE39590B1 (instruction)
LU (1) LU70467A1 (instruction)
NL (1) NL169478C (instruction)
PL (1) PL91389B1 (instruction)
SE (1) SE428565B (instruction)
YU (1) YU39525B (instruction)
ZA (1) ZA744314B (instruction)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053312B (it) * 1976-01-15 1981-08-31 Ankerfarm Spa Procedimento per la produzione di antibiotici di penicillina semisintetici
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
AT363594B (de) * 1978-02-01 1981-08-10 Biochemie Gmbh Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
YU44832B (en) * 1981-08-03 1991-04-30 Pliva Pharm & Chem Works Process for preparing semisynthetic cephalosporins
IT1180207B (it) * 1984-07-30 1987-09-23 Istituto Biochimico Italiano Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici
JPS6444608U (instruction) * 1987-09-11 1989-03-16
ZA887408B (en) * 1987-10-07 1990-06-27 Lilly Co Eli Monohydrate and solvates of a new beta-lactam antibiotic
US5091525A (en) * 1987-10-07 1992-02-25 Eli Lilly And Company Monohydrate and DMF solvates of a new carbacephem antibiotic

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34822B1 (en) * 1969-12-26 1975-08-20 Univ Osaka Process for producing 6-amino penicillanic acid
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
BE788582A (fr) * 1971-09-11 1973-03-08 Lilly Industries Ltd Procede de preparation de derives de cephalosporine
US3743644A (en) * 1972-02-28 1973-07-03 Bristol Myers Co 7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(isothiazol-3-,4-and 5-yl)carbonyl(thiomethyl-3-cephem-4-carboxylic acids
US3843639A (en) * 1973-02-08 1974-10-22 Bristol Myers Co Production of cephalexin via methoxymethyl ester

Also Published As

Publication number Publication date
HU169318B (instruction) 1976-11-28
YU39525B (en) 1984-12-31
DE2432485B2 (de) 1980-05-14
PL91389B1 (instruction) 1977-02-28
BE817266A (fr) 1975-01-06
NL7409050A (nl) 1975-01-07
JPS5069092A (instruction) 1975-06-09
DK144915B (da) 1982-07-05
DK144915C (da) 1982-11-22
CA1027555A (en) 1978-03-07
ZA744314B (en) 1975-07-30
IE39590B1 (en) 1978-11-08
DK358874A (instruction) 1975-03-03
LU70467A1 (instruction) 1974-11-28
CH601315A5 (instruction) 1978-07-14
DE2432485C3 (de) 1981-01-22
US3957773A (en) 1976-05-18
YU186274A (en) 1982-06-30
NL169478B (nl) 1982-02-16
AU7072274A (en) 1976-01-08
SE428565B (sv) 1983-07-11
FR2235943B1 (instruction) 1978-11-24
IE39590L (en) 1975-01-05
ATA552774A (de) 1977-05-15
FR2235943A1 (instruction) 1975-01-31
AT341085B (de) 1978-01-25
NL169478C (nl) 1982-07-16
SE7408833L (instruction) 1975-01-07
DE2432485A1 (de) 1975-01-30
ES427961A1 (es) 1976-12-01
JPS5318517B2 (instruction) 1978-06-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee