AT341085B - Verfahren zur herstellung eines bis-dimethylformamid-solvats von 7beta- (d-2-amino-2-phenylacetamido)-3-methylceph-3-em-4-carbonsaure (cephalexin) - Google Patents

Verfahren zur herstellung eines bis-dimethylformamid-solvats von 7beta- (d-2-amino-2-phenylacetamido)-3-methylceph-3-em-4-carbonsaure (cephalexin)

Info

Publication number
AT341085B
AT341085B AT552774A AT552774A AT341085B AT 341085 B AT341085 B AT 341085B AT 552774 A AT552774 A AT 552774A AT 552774 A AT552774 A AT 552774A AT 341085 B AT341085 B AT 341085B
Authority
AT
Austria
Prior art keywords
methylceph
solvat
7beta
phenylacetamido
cephalexin
Prior art date
Application number
AT552774A
Other languages
English (en)
Other versions
ATA552774A (de
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of ATA552774A publication Critical patent/ATA552774A/de
Application granted granted Critical
Publication of AT341085B publication Critical patent/AT341085B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT552774A 1973-07-05 1974-07-04 Verfahren zur herstellung eines bis-dimethylformamid-solvats von 7beta- (d-2-amino-2-phenylacetamido)-3-methylceph-3-em-4-carbonsaure (cephalexin) AT341085B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3211173A GB1472746A (en) 1973-07-05 1973-07-05 Cephalosporin compounds

Publications (2)

Publication Number Publication Date
ATA552774A ATA552774A (de) 1977-05-15
AT341085B true AT341085B (de) 1978-01-25

Family

ID=10333421

Family Applications (1)

Application Number Title Priority Date Filing Date
AT552774A AT341085B (de) 1973-07-05 1974-07-04 Verfahren zur herstellung eines bis-dimethylformamid-solvats von 7beta- (d-2-amino-2-phenylacetamido)-3-methylceph-3-em-4-carbonsaure (cephalexin)

Country Status (19)

Country Link
US (1) US3957773A (de)
JP (1) JPS5318517B2 (de)
AT (1) AT341085B (de)
BE (1) BE817266A (de)
CA (1) CA1027555A (de)
CH (1) CH601315A5 (de)
DE (1) DE2432485C3 (de)
DK (1) DK144915C (de)
ES (1) ES427961A1 (de)
FR (1) FR2235943B1 (de)
GB (1) GB1472746A (de)
HU (1) HU169318B (de)
IE (1) IE39590B1 (de)
LU (1) LU70467A1 (de)
NL (1) NL169478C (de)
PL (1) PL91389B1 (de)
SE (1) SE428565B (de)
YU (1) YU39525B (de)
ZA (1) ZA744314B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053312B (it) * 1976-01-15 1981-08-31 Ankerfarm Spa Procedimento per la produzione di antibiotici di penicillina semisintetici
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
AT363594B (de) * 1978-02-01 1981-08-10 Biochemie Gmbh Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
YU44832B (en) * 1981-08-03 1991-04-30 Pliva Pharm & Chem Works Process for preparing semisynthetic cephalosporins
IT1180207B (it) * 1984-07-30 1987-09-23 Istituto Biochimico Italiano Procedimento per la preparazione, con resa e purezza elevate, di antibiotici beta-lattamici
JPS6444608U (de) * 1987-09-11 1989-03-16
US5091525A (en) * 1987-10-07 1992-02-25 Eli Lilly And Company Monohydrate and DMF solvates of a new carbacephem antibiotic
MY103554A (en) * 1987-10-07 1993-07-31 Lilly Co Eli Manohydrate and solvates of a new (beta)-lactam antibiotic.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34822B1 (en) * 1969-12-26 1975-08-20 Univ Osaka Process for producing 6-amino penicillanic acid
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
BE788582A (fr) * 1971-09-11 1973-03-08 Lilly Industries Ltd Procede de preparation de derives de cephalosporine
US3743644A (en) * 1972-02-28 1973-07-03 Bristol Myers Co 7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(isothiazol-3-,4-and 5-yl)carbonyl(thiomethyl-3-cephem-4-carboxylic acids
US3843639A (en) * 1973-02-08 1974-10-22 Bristol Myers Co Production of cephalexin via methoxymethyl ester

Also Published As

Publication number Publication date
LU70467A1 (de) 1974-11-28
SE7408833L (de) 1975-01-07
IE39590L (en) 1975-01-05
JPS5069092A (de) 1975-06-09
GB1472746A (en) 1977-05-04
CA1027555A (en) 1978-03-07
HU169318B (de) 1976-11-28
BE817266A (fr) 1975-01-06
DE2432485C3 (de) 1981-01-22
FR2235943B1 (de) 1978-11-24
PL91389B1 (de) 1977-02-28
JPS5318517B2 (de) 1978-06-15
ZA744314B (en) 1975-07-30
DE2432485A1 (de) 1975-01-30
YU39525B (en) 1984-12-31
US3957773A (en) 1976-05-18
NL7409050A (nl) 1975-01-07
NL169478B (nl) 1982-02-16
IE39590B1 (en) 1978-11-08
AU7072274A (en) 1976-01-08
DK144915C (da) 1982-11-22
SE428565B (sv) 1983-07-11
NL169478C (nl) 1982-07-16
ES427961A1 (es) 1976-12-01
DK144915B (da) 1982-07-05
CH601315A5 (de) 1978-07-14
ATA552774A (de) 1977-05-15
DE2432485B2 (de) 1980-05-14
YU186274A (en) 1982-06-30
DK358874A (de) 1975-03-03
FR2235943A1 (de) 1975-01-31

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