GB1470277A - Stabilized n2,2-o-dibutyrylguanosine-3,5-cyclic phosphate and salts thereof - Google Patents
Stabilized n2,2-o-dibutyrylguanosine-3,5-cyclic phosphate and salts thereofInfo
- Publication number
- GB1470277A GB1470277A GB1757175A GB1757175A GB1470277A GB 1470277 A GB1470277 A GB 1470277A GB 1757175 A GB1757175 A GB 1757175A GB 1757175 A GB1757175 A GB 1757175A GB 1470277 A GB1470277 A GB 1470277A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stabilized
- cyclic phosphate
- salts
- desiccation
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 6
- 229910019142 PO4 Inorganic materials 0.000 title abstract 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title abstract 4
- 239000010452 phosphate Substances 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- -1 Na or K) Chemical compound 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 229910052788 barium Inorganic materials 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 239000002274 desiccant Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49052866A JPS50142595A (cg-RX-API-DMAC7.html) | 1974-05-14 | 1974-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1470277A true GB1470277A (en) | 1977-04-14 |
Family
ID=12926778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1757175A Expired GB1470277A (en) | 1974-05-14 | 1975-04-28 | Stabilized n2,2-o-dibutyrylguanosine-3,5-cyclic phosphate and salts thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4054735A (cg-RX-API-DMAC7.html) |
| JP (1) | JPS50142595A (cg-RX-API-DMAC7.html) |
| CA (1) | CA1032936A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2521064A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2271232B1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1470277A (cg-RX-API-DMAC7.html) |
| NL (1) | NL7505582A (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2740362B2 (ja) * | 1991-02-12 | 1998-04-15 | ヤマサ醤油株式会社 | 安定な固体状２‐オクチニルアデノシンおよびその製造法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3190877A (en) * | 1962-02-15 | 1965-06-22 | Takeda Chemical Industries Ltd | Crystalline sodium salt of 5'-guanylic acid and a method for preparing the same |
| US3712885A (en) * | 1968-09-10 | 1973-01-23 | G Weimann | Purine-ribofuranoside-3',5'-cyclophosphates and process for their preparation |
| GB1336441A (en) * | 1969-10-10 | 1973-11-07 | Anvar | Derivatives of cyclo adenosine-3,5-phosphoric acid and their preparation |
| US3852267A (en) * | 1972-08-04 | 1974-12-03 | Icn Pharmaceuticals | Phosphoramidates of 3{40 ,5{40 -cyclic purine nucleotides |
| GB1396920A (en) * | 1972-10-06 | 1975-06-11 | Dorman Smith Britmac Ltd | Electrical outlet unit |
| JPS5134443B2 (cg-RX-API-DMAC7.html) * | 1972-10-09 | 1976-09-27 |
-
1974
- 1974-05-14 JP JP49052866A patent/JPS50142595A/ja active Pending
-
1975
- 1975-04-28 GB GB1757175A patent/GB1470277A/en not_active Expired
- 1975-04-30 US US05/573,157 patent/US4054735A/en not_active Expired - Lifetime
- 1975-05-12 CA CA226,721A patent/CA1032936A/en not_active Expired
- 1975-05-12 DE DE19752521064 patent/DE2521064A1/de not_active Ceased
- 1975-05-13 FR FR7514773A patent/FR2271232B1/fr not_active Expired
- 1975-05-13 NL NL7505582A patent/NL7505582A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4054735A (en) | 1977-10-18 |
| FR2271232B1 (cg-RX-API-DMAC7.html) | 1977-04-15 |
| NL7505582A (nl) | 1975-11-18 |
| JPS50142595A (cg-RX-API-DMAC7.html) | 1975-11-17 |
| FR2271232A1 (cg-RX-API-DMAC7.html) | 1975-12-12 |
| CA1032936A (en) | 1978-06-13 |
| DE2521064A1 (de) | 1975-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |