GB1467763A - 2-substituted thio-1,4-benzodiazepine derivatives - Google Patents
2-substituted thio-1,4-benzodiazepine derivativesInfo
- Publication number
- GB1467763A GB1467763A GB1151875A GB1151875A GB1467763A GB 1467763 A GB1467763 A GB 1467763A GB 1151875 A GB1151875 A GB 1151875A GB 1151875 A GB1151875 A GB 1151875A GB 1467763 A GB1467763 A GB 1467763A
- Authority
- GB
- United Kingdom
- Prior art keywords
- march
- alkyl
- compounds
- benzodiazepine derivatives
- substituted thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- YPXQSGWOGQPLQO-UHFFFAOYSA-N 5-nitro-1,3-dihydrobenzimidazole-2-thione Chemical compound [O-][N+](=O)C1=CC=C2N=C(S)NC2=C1 YPXQSGWOGQPLQO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/22—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49031905A JPS5919099B2 (ja) | 1974-03-20 | 1974-03-20 | ２−置換チオ−１，４−ベンゾジアゼピン誘導体の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1467763A true GB1467763A (en) | 1977-03-23 |
Family
ID=12344003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1151875A Expired GB1467763A (en) | 1974-03-20 | 1975-03-19 | 2-substituted thio-1,4-benzodiazepine derivatives |
Country Status (15)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094870A (en) * | 1974-03-20 | 1978-06-13 | Fujisawa Pharmaceutical Co., Ltd. | 2-Substituted thio-1,4-benzodiazepine derivatives |
| HU224435B1 (hu) * | 1995-02-09 | 2005-10-28 | EGIS Gyógyszergyár Rt. | Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények |
-
1974
- 1974-03-20 JP JP49031905A patent/JPS5919099B2/ja not_active Expired
-
1975
- 1975-03-18 BE BE154448A patent/BE826817A/xx unknown
- 1975-03-18 HU HUFU333A patent/HU170141B/hu unknown
- 1975-03-19 CA CA222,537A patent/CA1064029A/en not_active Expired
- 1975-03-19 SE SE7503164A patent/SE7503164L/xx unknown
- 1975-03-19 DK DK114175A patent/DK114175A/da unknown
- 1975-03-19 NO NO750943A patent/NO750943L/no unknown
- 1975-03-19 FI FI750816A patent/FI750816A7/fi not_active Application Discontinuation
- 1975-03-19 ZA ZA00751715A patent/ZA751715B/xx unknown
- 1975-03-19 GB GB1151875A patent/GB1467763A/en not_active Expired
- 1975-03-19 AU AU79298/75A patent/AU7929875A/en not_active Expired
- 1975-03-19 NL NL7503269A patent/NL7503269A/xx unknown
- 1975-03-19 DE DE19752511898 patent/DE2511898A1/de not_active Withdrawn
- 1975-03-19 FR FR7508599A patent/FR2264545B1/fr not_active Expired
- 1975-03-20 ES ES435812A patent/ES435812A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2511898A1 (de) | 1975-09-25 |
| NL7503269A (nl) | 1975-09-23 |
| HU170141B (enrdf_load_stackoverflow) | 1977-04-28 |
| ZA751715B (en) | 1976-02-25 |
| BE826817A (fr) | 1975-09-18 |
| FR2264545A1 (enrdf_load_stackoverflow) | 1975-10-17 |
| NO750943L (enrdf_load_stackoverflow) | 1975-09-23 |
| FR2264545B1 (enrdf_load_stackoverflow) | 1978-08-04 |
| CA1064029A (en) | 1979-10-09 |
| SE7503164L (enrdf_load_stackoverflow) | 1975-09-22 |
| AU7929875A (en) | 1976-09-23 |
| JPS5919099B2 (ja) | 1984-05-02 |
| FI750816A7 (enrdf_load_stackoverflow) | 1975-09-21 |
| ES435812A1 (es) | 1976-12-01 |
| DK114175A (enrdf_load_stackoverflow) | 1975-09-21 |
| JPS50131980A (enrdf_load_stackoverflow) | 1975-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |