GB1464509A - Esters of steroid 21-ols - Google Patents

Esters of steroid 21-ols

Info

Publication number
GB1464509A
GB1464509A GB3209875A GB3209875A GB1464509A GB 1464509 A GB1464509 A GB 1464509A GB 3209875 A GB3209875 A GB 3209875A GB 3209875 A GB3209875 A GB 3209875A GB 1464509 A GB1464509 A GB 1464509A
Authority
GB
United Kingdom
Prior art keywords
steroid
esters
ols
prepared
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3209875A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rorer Italiana SpA
Original Assignee
Rorer Italiana SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer Italiana SpA filed Critical Rorer Italiana SpA
Publication of GB1464509A publication Critical patent/GB1464509A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1464509 Esters of steroid 21-ols with 4-N- acetylaminomethylcyclohexane carboxylic acid RORER ITALIANA SpA 31 July 1975 [1 Aug 1974] 32098/75 Headings C2U and C2C Novel steroid 21-esters have the formula wherein St is a steroid group of the pregnane, pregnene or pregnadiene series, the ester linkage being at position 21 of the steroid group. They are prepared from the free 21-ols and 4-N- acetylaminomethyl-cyclohexanecarboxylic acid chloride. The novel esters are anti-inflammatory steroids and they are made up into pharmaceutical compositions with suitable carriers. 4 - AT - Acetylaminomethylcyclohexanecarboxylic acid is prepared from the corresponding free amine and acetic anhydride and is converted to the acid chloride by the action of SOCl 2 .
GB3209875A 1974-08-01 1975-07-31 Esters of steroid 21-ols Expired GB1464509A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7426769A FR2280384A1 (en) 1974-08-01 1974-08-01 STEROID DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATIONS

Publications (1)

Publication Number Publication Date
GB1464509A true GB1464509A (en) 1977-02-16

Family

ID=9141988

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3209875A Expired GB1464509A (en) 1974-08-01 1975-07-31 Esters of steroid 21-ols

Country Status (6)

Country Link
JP (1) JPS5148650A (en)
BE (1) BE831826A (en)
CA (1) CA1061778A (en)
DE (1) DE2533929A1 (en)
FR (1) FR2280384A1 (en)
GB (1) GB1464509A (en)

Also Published As

Publication number Publication date
CA1061778A (en) 1979-09-04
FR2280384B1 (en) 1978-07-21
BE831826A (en) 1976-01-28
FR2280384A1 (en) 1976-02-27
JPS5148650A (en) 1976-04-26
DE2533929A1 (en) 1976-03-11

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Legal Events

Date Code Title Description
PS Patent sealed
746 Register noted 'licences of right' (sect. 46/1977)
PCNP Patent ceased through non-payment of renewal fee