GB1462387A - Aminoglycosides - Google Patents
AminoglycosidesInfo
- Publication number
- GB1462387A GB1462387A GB1920974A GB1920974A GB1462387A GB 1462387 A GB1462387 A GB 1462387A GB 1920974 A GB1920974 A GB 1920974A GB 1920974 A GB1920974 A GB 1920974A GB 1462387 A GB1462387 A GB 1462387A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trifluoroacetamido
- trifluoroacetyl
- eropyranose
- tetradeoxy
- lyxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940126575 aminoglycoside Drugs 0.000 title 1
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- ZXSQEZNORDWBGZ-UHFFFAOYSA-N 1,3-dihydropyrrolo[2,3-b]pyridin-2-one Chemical compound C1=CN=C2NC(=O)CC2=C1 ZXSQEZNORDWBGZ-UHFFFAOYSA-N 0.000 abstract 1
- RTKMFQOHBDVEBC-UHFFFAOYSA-N 3-bromo-3-buten-1-ol Chemical compound OCCC(Br)=C RTKMFQOHBDVEBC-UHFFFAOYSA-N 0.000 abstract 1
- STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 abstract 1
- WEAHRLBPCANXCN-UHFFFAOYSA-N Daunomycin Natural products CCC1(O)CC(OC2CC(N)C(O)C(C)O2)c3cc4C(=O)c5c(OC)cccc5C(=O)c4c(O)c3C1 WEAHRLBPCANXCN-UHFFFAOYSA-N 0.000 abstract 1
- 101150026303 HEX1 gene Proteins 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 229940009456 adriamycin Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
- 229940075610 mercuric cyanide Drugs 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 229910001958 silver carbonate Inorganic materials 0.000 abstract 1
- LKZMBDSASOBTPN-UHFFFAOYSA-L silver carbonate Substances [Ag].[O-]C([O-])=O LKZMBDSASOBTPN-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1920974A GB1462387A (en) | 1974-05-02 | 1974-05-02 | Aminoglycosides |
| SU752127951A SU650507A3 (ru) | 1974-05-02 | 1975-04-28 | Способ получени гликозидных антибиотиков или их гидрохлоридов |
| FR7513362A FR2269536B1 (enExample) | 1974-05-02 | 1975-04-29 | |
| JP50051593A JPS5840556B2 (ja) | 1974-05-02 | 1975-04-30 | コウシユヨウセイカゴウブツノゴウセイホウ |
| DE2519157A DE2519157C2 (de) | 1974-05-02 | 1975-04-30 | Verfahren zur Herstellung von Anthracyclinglycosiden |
| US05/650,519 US4020270A (en) | 1974-05-02 | 1976-01-19 | L-lyxohex-1-enopyranose derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1920974A GB1462387A (en) | 1974-05-02 | 1974-05-02 | Aminoglycosides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1462387A true GB1462387A (en) | 1977-01-26 |
Family
ID=10125549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1920974A Expired GB1462387A (en) | 1974-05-02 | 1974-05-02 | Aminoglycosides |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5840556B2 (enExample) |
| DE (1) | DE2519157C2 (enExample) |
| FR (1) | FR2269536B1 (enExample) |
| GB (1) | GB1462387A (enExample) |
| SU (1) | SU650507A3 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1098211B (it) * | 1978-05-09 | 1985-09-07 | Farmaceutici Italia | Deossiantracicline antitumorali |
| DE3172152D1 (en) * | 1980-11-01 | 1985-10-10 | Erba Farmitalia | Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions |
| US4562177A (en) * | 1982-08-17 | 1985-12-31 | The Ohio State University Research Foundation | 3'-Amino-2' halo-anthracycline antibiotics |
| FR2565982B1 (fr) * | 1984-06-15 | 1988-01-15 | Hoechst Lab | Nouveaux amino-3-tridesoxy-3,4,6-glycals, leurs procedes de preparation et anthracyclines obtenues a l'aide de ces glycals |
| US4697005A (en) * | 1985-03-20 | 1987-09-29 | Ohio State University Research Foundation | 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics |
| RU2249421C2 (ru) * | 2003-04-08 | 2005-04-10 | Филатов Сергей Иванович | Зонт с каркасом в два сложения |
-
1974
- 1974-05-02 GB GB1920974A patent/GB1462387A/en not_active Expired
-
1975
- 1975-04-28 SU SU752127951A patent/SU650507A3/ru active
- 1975-04-29 FR FR7513362A patent/FR2269536B1/fr not_active Expired
- 1975-04-30 JP JP50051593A patent/JPS5840556B2/ja not_active Expired
- 1975-04-30 DE DE2519157A patent/DE2519157C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SU650507A3 (ru) | 1979-02-28 |
| FR2269536B1 (enExample) | 1977-07-08 |
| DE2519157A1 (de) | 1975-11-20 |
| FR2269536A1 (enExample) | 1975-11-28 |
| DE2519157C2 (de) | 1983-11-10 |
| JPS50149663A (enExample) | 1975-11-29 |
| JPS5840556B2 (ja) | 1983-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 416 | Proceeding under section 16 patents act 1949 | ||
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |