GB1461948A - 7-substituted-3-amino-alkyl-acylaminoalkyl-or hydroxyalkyl- substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof - Google Patents

7-substituted-3-amino-alkyl-acylaminoalkyl-or hydroxyalkyl- substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof

Info

Publication number
GB1461948A
GB1461948A GB1414374A GB1414374A GB1461948A GB 1461948 A GB1461948 A GB 1461948A GB 1414374 A GB1414374 A GB 1414374A GB 1414374 A GB1414374 A GB 1414374A GB 1461948 A GB1461948 A GB 1461948A
Authority
GB
United Kingdom
Prior art keywords
substituted
acylaminoalkyl
hydroxyalkyl
carboxylic acid
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1414374A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP48037205A external-priority patent/JPS5939439B2/ja
Priority claimed from JP48073898A external-priority patent/JPS5852997B2/ja
Priority claimed from JP13936473A external-priority patent/JPS5716118B2/ja
Priority claimed from JP741096A external-priority patent/JPS5734837B2/ja
Priority claimed from JP1308374A external-priority patent/JPS5732074B2/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of GB1461948A publication Critical patent/GB1461948A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
GB1414374A 1973-03-30 1974-03-29 7-substituted-3-amino-alkyl-acylaminoalkyl-or hydroxyalkyl- substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof Expired GB1461948A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP48037205A JPS5939439B2 (ja) 1973-03-30 1973-03-30 ７−置換−３−ｎ，ｓ含有複素環チオメチル−３−セフエム−４−カルボン酸誘導体の製造法
JP48073898A JPS5852997B2 (ja) 1973-06-29 1973-06-29 ７− チカン −３− ヒドロキシアルキルチカンフクソカンチオメチル −３− セフエム −４− カルボンサンルイノ セイゾウホウ
JP13936473A JPS5716118B2 (enrdf_load_stackoverflow) 1973-12-12 1973-12-12
JP741096A JPS5734837B2 (enrdf_load_stackoverflow) 1973-12-26 1973-12-26
JP1308374A JPS5732074B2 (enrdf_load_stackoverflow) 1974-01-30 1974-01-30

Publications (1)

Publication Number Publication Date
GB1461948A true GB1461948A (en) 1977-01-19

Family

ID=27518056

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1414374A Expired GB1461948A (en) 1973-03-30 1974-03-29 7-substituted-3-amino-alkyl-acylaminoalkyl-or hydroxyalkyl- substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof

Country Status (10)

Country Link
AR (1) AR207752A1 (enrdf_load_stackoverflow)
BE (1) BE812951A (enrdf_load_stackoverflow)
CH (3) CH595388A5 (enrdf_load_stackoverflow)
DE (1) DE2415402C2 (enrdf_load_stackoverflow)
FR (1) FR2223002B1 (enrdf_load_stackoverflow)
GB (1) GB1461948A (enrdf_load_stackoverflow)
NL (1) NL180422C (enrdf_load_stackoverflow)
NO (2) NO741137L (enrdf_load_stackoverflow)
NZ (1) NZ173837A (enrdf_load_stackoverflow)
SE (1) SE428297B (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379924A (en) 1973-12-25 1983-04-12 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
WO2001044186A1 (fr) * 1999-12-16 2001-06-21 Sumitomo Pharmaceuticals Company, Limited Derives de guanidine substitues

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093723A (en) 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
BE845338A (fr) * 1975-09-02 1977-02-21 Nouvelles cephalosporines, procede pour leur obtention et application pharmaceutique
US4171368A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
US4118491A (en) * 1976-03-11 1978-10-03 Smithkline Corporation 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4171433A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins
IL50546A (en) * 1975-10-30 1980-07-31 Smithkline Corp 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4101656A (en) 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4083975A (en) 1976-09-24 1978-04-11 Smithkline Corporation 7-Acylamino-3-(3-sulfomethyl-1,2,4-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4064242A (en) * 1976-11-04 1977-12-20 Smithkline Corporation 7-Acylamino-3-[1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4260815A (en) 1979-10-09 1981-04-07 American Cyanamid Company Process for preparing a solution of DL-mandelic acid
US4259521A (en) 1979-10-09 1981-03-31 American Cyanamid Company Process for resolving DL-mandelic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
DE1953861C2 (de) * 1969-10-25 1982-12-23 Fujisawa Pharmaceutical Co., Ltd., Osaka 7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren
US3757014A (en) * 1971-05-07 1973-09-04 Bristol Myers Co Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl -

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379924A (en) 1973-12-25 1983-04-12 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
WO2001044186A1 (fr) * 1999-12-16 2001-06-21 Sumitomo Pharmaceuticals Company, Limited Derives de guanidine substitues
US6734205B2 (en) 1999-12-16 2004-05-11 Sumitomo Pharmaceuticals Company Limited Substituted guanidine derivatives

Also Published As

Publication number Publication date
FR2223002A1 (enrdf_load_stackoverflow) 1974-10-25
DE2415402A1 (de) 1974-10-03
NZ173837A (en) 1978-07-28
NO801402L (no) 1974-10-01
FR2223002B1 (enrdf_load_stackoverflow) 1977-11-04
AU6735374A (en) 1975-10-02
NL180422B (nl) 1986-09-16
CH610902A5 (en) 1979-05-15
SE428297B (sv) 1983-06-20
DE2415402C2 (de) 1985-12-19
CH595388A5 (enrdf_load_stackoverflow) 1978-02-15
SE7404306L (enrdf_load_stackoverflow) 1974-10-01
NO741137L (no) 1974-10-01
CH610903A5 (en) 1979-05-15
NL180422C (nl) 1987-02-16
NL7404330A (enrdf_load_stackoverflow) 1974-10-02
BE812951A (fr) 1974-09-30
AR207752A1 (es) 1976-10-29

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee