GB1460302A - Tablet formulation - Google Patents

Tablet formulation

Info

Publication number
GB1460302A
GB1460302A GB2462873A GB2462873A GB1460302A GB 1460302 A GB1460302 A GB 1460302A GB 2462873 A GB2462873 A GB 2462873A GB 2462873 A GB2462873 A GB 2462873A GB 1460302 A GB1460302 A GB 1460302A
Authority
GB
United Kingdom
Prior art keywords
allopurinol
agent
starch
tablet formulations
disintegrating agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2462873A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB2462873A priority Critical patent/GB1460302A/en
Priority to NLAANVRAGE7406873,A priority patent/NL190436C/en
Priority to BE144636A priority patent/BE815409A/en
Priority to FR7417820A priority patent/FR2230341B1/fr
Priority to AU69252/74A priority patent/AU469472B2/en
Priority to CA200,536A priority patent/CA977279A/en
Priority to HUWE507A priority patent/HU170656B/hu
Priority to IL44877A priority patent/IL44877A/en
Priority to DE19742424950 priority patent/DE2424950A1/en
Priority to DK280174AA priority patent/DK144261C/en
Priority to SE7406864A priority patent/SE402525C/en
Priority to IE1097/74A priority patent/IE39283B1/en
Priority to FI1566/74A priority patent/FI156674A/fi
Priority to AT426774A priority patent/AT351167B/en
Priority to JP5776774A priority patent/JPS577128B2/ja
Priority to ZA00743318A priority patent/ZA743318B/en
Priority to CY941A priority patent/CY941A/en
Priority to KE2808A priority patent/KE2808A/en
Publication of GB1460302A publication Critical patent/GB1460302A/en
Priority to HK13/78A priority patent/HK1378A/en
Priority to MY1978181A priority patent/MY7800181A/en
Priority to IT8048966A priority patent/IT8048966A0/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Abstract

1460302 Allopurinol tablet formulations WELLCOME FOUNDATION Ltd 23 May 1974 [23 May 1973] 24628/73 Heading A5B Tablet formulations comprise from 80 to 98% w/w of allopurinol (4-hydroxy pyrazolo (3, 4-d) pyrimidine) having a particle size from 2 to 40Ám, from 1 to 19% w/w of a disintegrating agent and from 1 to 19% of a granulating agent. The disintegrating agent may be alginic acid, a sodium starch glycolate, a guar-based vegetable gum or calcium carboxymethyl cellulose and the granulating agent may be starch mucilage, a starch derivative, a cellulose derivative, polyvinylpyrrolidine or gelatin. The formulations are compressed on standard machinery to form tablets for use in treating gout and other hyperuricaemic conditions.
GB2462873A 1973-05-23 1973-05-23 Tablet formulation Expired GB1460302A (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
GB2462873A GB1460302A (en) 1973-05-23 1973-05-23 Tablet formulation
IE1097/74A IE39283B1 (en) 1973-05-23 1974-05-22 Tablet formulation
FI1566/74A FI156674A (en) 1973-05-23 1974-05-22
BE144636A BE815409A (en) 1973-05-23 1974-05-22 PHARMACEUTICAL COMPOSITIONS CONTAINING XANTHINE OXIDASE INHIBITORS
AU69252/74A AU469472B2 (en) 1973-05-23 1974-05-22 Tablet formulation
CA200,536A CA977279A (en) 1973-05-23 1974-05-22 Tablet formulation containing a high percentage of allopurinol
HUWE507A HU170656B (en) 1973-05-23 1974-05-22
IL44877A IL44877A (en) 1973-05-23 1974-05-22 Allopurinol tablet formulation
DE19742424950 DE2424950A1 (en) 1973-05-23 1974-05-22 PHARMACEUTICAL PREPARATIONS CONTAINING ALLOPURINOL AND THE METHOD FOR THEIR MANUFACTURING
AT426774A AT351167B (en) 1973-05-23 1974-05-22 METHOD FOR PRODUCING ALLOPURINOL-CONTAINING TABLETS
SE7406864A SE402525C (en) 1973-05-23 1974-05-22 Process for the preparation of tablets with a short dissolution time containing allopurinol
NLAANVRAGE7406873,A NL190436C (en) 1973-05-23 1974-05-22 A method of preparing a pharmaceutical tablet formulation containing allopurinol.
FR7417820A FR2230341B1 (en) 1973-05-23 1974-05-22
DK280174AA DK144261C (en) 1973-05-23 1974-05-22 Medical tablet containing allopurinol
JP5776774A JPS577128B2 (en) 1973-05-23 1974-05-22
ZA00743318A ZA743318B (en) 1973-05-23 1974-05-22 Tablet formulation
CY941A CY941A (en) 1973-05-23 1974-05-23 Tablet formulation
KE2808A KE2808A (en) 1973-05-23 1974-12-02 Tablet formulation
HK13/78A HK1378A (en) 1973-05-23 1978-01-05 Tablet formulation
MY1978181A MY7800181A (en) 1973-05-23 1978-12-31 Tablet formulation
IT8048966A IT8048966A0 (en) 1973-05-23 1980-06-13 PHARMACEUTICAL COMPOSITION CONTAINING ALLOPURINOL AND PREPARATION PROCEDURE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2462873A GB1460302A (en) 1973-05-23 1973-05-23 Tablet formulation

Publications (1)

Publication Number Publication Date
GB1460302A true GB1460302A (en) 1977-01-06

Family

ID=10214700

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2462873A Expired GB1460302A (en) 1973-05-23 1973-05-23 Tablet formulation

Country Status (21)

Country Link
JP (1) JPS577128B2 (en)
AT (1) AT351167B (en)
AU (1) AU469472B2 (en)
BE (1) BE815409A (en)
CA (1) CA977279A (en)
CY (1) CY941A (en)
DE (1) DE2424950A1 (en)
DK (1) DK144261C (en)
FI (1) FI156674A (en)
FR (1) FR2230341B1 (en)
GB (1) GB1460302A (en)
HK (1) HK1378A (en)
HU (1) HU170656B (en)
IE (1) IE39283B1 (en)
IL (1) IL44877A (en)
IT (1) IT8048966A0 (en)
KE (1) KE2808A (en)
MY (1) MY7800181A (en)
NL (1) NL190436C (en)
SE (1) SE402525C (en)
ZA (1) ZA743318B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1533243A (en) * 1975-02-13 1978-11-22 Wellcome Found Tablet formulation
US4143129A (en) 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
US4115563A (en) * 1977-03-14 1978-09-19 Sterling Drug Inc. Pharmaceutical steroid formulation
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
DE3839825A1 (en) * 1988-11-25 1990-06-13 Henning Berlin Gmbh SOLIDS DISPERSIONS CONTAIN OXIPURINOL AND / OR ITS ALKALI OR EARTH ALKALISALZE
EP0719547A1 (en) * 1994-07-18 1996-07-03 Luis Cipriano Carvajal Martin Self-desintegrating compact granules used in galenic forms and containing active insoluble or hardly soluble principles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB975850A (en) * 1955-08-10 1964-11-18 Wellcome Found Xanthine oxidase inhibitors
US3624205A (en) * 1967-04-25 1971-11-30 Burroughs Wellcome Co Treatment of hyperuricemia in humans

Also Published As

Publication number Publication date
FR2230341A1 (en) 1974-12-20
AU469472B2 (en) 1976-02-12
IL44877A (en) 1976-11-30
SE402525B (en) 1978-07-10
FI156674A (en) 1974-11-24
NL7406873A (en) 1974-11-26
IL44877A0 (en) 1974-07-31
IE39283B1 (en) 1978-09-13
FR2230341B1 (en) 1977-04-15
NL190436B (en) 1993-10-01
ZA743318B (en) 1975-05-28
IT8048966A0 (en) 1980-06-13
CA977279A (en) 1975-11-04
JPS5040721A (en) 1975-04-14
HK1378A (en) 1978-01-13
AT351167B (en) 1979-07-10
DK144261B (en) 1982-02-01
SE402525C (en) 1982-09-15
NL190436C (en) 1994-03-01
IE39283L (en) 1974-11-23
AU6925274A (en) 1975-11-27
JPS577128B2 (en) 1982-02-09
HU170656B (en) 1977-07-28
CY941A (en) 1978-06-23
ATA426774A (en) 1978-12-15
BE815409A (en) 1974-11-22
DK144261C (en) 1991-02-04
KE2808A (en) 1978-02-17
MY7800181A (en) 1978-12-31
DE2424950A1 (en) 1974-12-19

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19940522