IE39283B1 - Tablet formulation - Google Patents

Tablet formulation

Info

Publication number
IE39283B1
IE39283B1 IE1097/74A IE109774A IE39283B1 IE 39283 B1 IE39283 B1 IE 39283B1 IE 1097/74 A IE1097/74 A IE 1097/74A IE 109774 A IE109774 A IE 109774A IE 39283 B1 IE39283 B1 IE 39283B1
Authority
IE
Ireland
Prior art keywords
allopurinol
agent
starch
tablet formulations
disintegrating agent
Prior art date
Application number
IE1097/74A
Other versions
IE39283L (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE39283L publication Critical patent/IE39283L/en
Publication of IE39283B1 publication Critical patent/IE39283B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1460302 Allopurinol tablet formulations WELLCOME FOUNDATION Ltd 23 May 1974 [23 May 1973] 24628/73 Heading A5B Tablet formulations comprise from 80 to 98% w/w of allopurinol (4-hydroxy pyrazolo (3, 4-d) pyrimidine) having a particle size from 2 to 40Ám, from 1 to 19% w/w of a disintegrating agent and from 1 to 19% of a granulating agent. The disintegrating agent may be alginic acid, a sodium starch glycolate, a guar-based vegetable gum or calcium carboxymethyl cellulose and the granulating agent may be starch mucilage, a starch derivative, a cellulose derivative, polyvinylpyrrolidine or gelatin. The formulations are compressed on standard machinery to form tablets for use in treating gout and other hyperuricaemic conditions. [GB1460302A]
IE1097/74A 1973-05-23 1974-05-22 Tablet formulation IE39283B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2462873A GB1460302A (en) 1973-05-23 1973-05-23 Tablet formulation

Publications (2)

Publication Number Publication Date
IE39283L IE39283L (en) 1974-11-23
IE39283B1 true IE39283B1 (en) 1978-09-13

Family

ID=10214700

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1097/74A IE39283B1 (en) 1973-05-23 1974-05-22 Tablet formulation

Country Status (21)

Country Link
JP (1) JPS577128B2 (en)
AT (1) AT351167B (en)
AU (1) AU469472B2 (en)
BE (1) BE815409A (en)
CA (1) CA977279A (en)
CY (1) CY941A (en)
DE (1) DE2424950A1 (en)
DK (1) DK144261C (en)
FI (1) FI156674A (en)
FR (1) FR2230341B1 (en)
GB (1) GB1460302A (en)
HK (1) HK1378A (en)
HU (1) HU170656B (en)
IE (1) IE39283B1 (en)
IL (1) IL44877A (en)
IT (1) IT8048966A0 (en)
KE (1) KE2808A (en)
MY (1) MY7800181A (en)
NL (1) NL190436C (en)
SE (1) SE402525C (en)
ZA (1) ZA743318B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1533243A (en) * 1975-02-13 1978-11-22 Wellcome Found Tablet formulation
US4143129A (en) 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
US4115563A (en) * 1977-03-14 1978-09-19 Sterling Drug Inc. Pharmaceutical steroid formulation
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
DE3839825A1 (en) * 1988-11-25 1990-06-13 Henning Berlin Gmbh SOLIDS DISPERSIONS CONTAIN OXIPURINOL AND / OR ITS ALKALI OR EARTH ALKALISALZE
EP0719547A1 (en) * 1994-07-18 1996-07-03 Luis Cipriano Carvajal Martin Self-desintegrating compact granules used in galenic forms and containing active insoluble or hardly soluble principles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB975850A (en) * 1955-08-10 1964-11-18 Wellcome Found Xanthine oxidase inhibitors
US3624205A (en) * 1967-04-25 1971-11-30 Burroughs Wellcome Co Treatment of hyperuricemia in humans

Also Published As

Publication number Publication date
GB1460302A (en) 1977-01-06
JPS5040721A (en) 1975-04-14
AU469472B2 (en) 1976-02-12
ATA426774A (en) 1978-12-15
NL7406873A (en) 1974-11-26
DK144261B (en) 1982-02-01
AU6925274A (en) 1975-11-27
IE39283L (en) 1974-11-23
MY7800181A (en) 1978-12-31
DK144261C (en) 1991-02-04
BE815409A (en) 1974-11-22
FI156674A (en) 1974-11-24
IT8048966A0 (en) 1980-06-13
FR2230341A1 (en) 1974-12-20
KE2808A (en) 1978-02-17
DE2424950A1 (en) 1974-12-19
HK1378A (en) 1978-01-13
IL44877A0 (en) 1974-07-31
AT351167B (en) 1979-07-10
HU170656B (en) 1977-07-28
FR2230341B1 (en) 1977-04-15
CA977279A (en) 1975-11-04
SE402525C (en) 1982-09-15
NL190436B (en) 1993-10-01
IL44877A (en) 1976-11-30
CY941A (en) 1978-06-23
NL190436C (en) 1994-03-01
ZA743318B (en) 1975-05-28
JPS577128B2 (en) 1982-02-09
SE402525B (en) 1978-07-10

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