GB1446084A - Substituted acylanilides - Google Patents

Substituted acylanilides

Info

Publication number
GB1446084A
GB1446084A GB5379073A GB5379073A GB1446084A GB 1446084 A GB1446084 A GB 1446084A GB 5379073 A GB5379073 A GB 5379073A GB 5379073 A GB5379073 A GB 5379073A GB 1446084 A GB1446084 A GB 1446084A
Authority
GB
United Kingdom
Prior art keywords
compounds
amino
groups
loweralkoxy
loweralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5379073A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of GB1446084A publication Critical patent/GB1446084A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB5379073A 1972-11-24 1973-11-20 Substituted acylanilides Expired GB1446084A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30953972A 1972-11-24 1972-11-24
US371452A US3875229A (en) 1972-11-24 1973-06-19 Substituted carboxanilides

Publications (1)

Publication Number Publication Date
GB1446084A true GB1446084A (en) 1976-08-11

Family

ID=26976880

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5379073A Expired GB1446084A (en) 1972-11-24 1973-11-20 Substituted acylanilides

Country Status (12)

Country Link
US (1) US3875229A ( )
JP (1) JPS4981332A ( )
BG (1) BG21392A3 ( )
DD (1) DD110856A5 ( )
DE (1) DE2357757A1 ( )
ES (1) ES420688A1 ( )
FR (1) FR2207712B1 ( )
GB (1) GB1446084A ( )
HU (1) HU169277B ( )
IE (1) IE38530B1 ( )
IL (1) IL43664A0 ( )
NL (1) NL7315903A ( )

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003619A2 (en) * 1978-01-09 1979-08-22 Shell Internationale Researchmaatschappij B.V. Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them
US8552061B2 (en) 2007-05-03 2013-10-08 Yale University Locally active “soft” antiandrogens

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* Cited by examiner, † Cited by third party
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US4149874A (en) * 1977-06-21 1979-04-17 Stauffer Chemical Company Substituted cyclopropylmethoxy anilides and their use as herbicides
US4356026A (en) * 1977-06-21 1982-10-26 Stauffer Chemical Company Substituted cyclopropylmethoxy phenyl ureas and their use as herbicides
US4230483A (en) * 1977-06-21 1980-10-28 Stauffer Chemical Company Substituted cyclopropylmethoxy phenyl carbamates and thiocarbamates and their use as herbicides
DE2862100D1 (en) * 1977-10-12 1983-01-05 Ici Plc Acylanilides, process for their manufacture and pharmaceutical and veterinary compositions containing them
US4191775A (en) * 1977-12-15 1980-03-04 Imperial Chemical Industries Limited Amide derivatives
LU88769I2 (fr) * 1982-07-23 1996-11-05 Zeneca Ltd Bicalutamide et ses sels et esters pharmaceutiquement acceptables (Casodex (R))
GB8617652D0 (en) * 1986-07-18 1986-08-28 Ici Plc Acylanilide derivatives
US4921941A (en) * 1987-07-01 1990-05-01 Schering Corporation Orally active antiandrogens
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
AU4966497A (en) * 1996-11-18 1998-06-10 Yamanouchi Pharmaceutical Co., Ltd. Novel acylamino-substituted acylanilide derivatives or pharmaceutical composition comprising the same
US20050038110A1 (en) * 2000-08-24 2005-02-17 Steiner Mitchell S. Selective androgen receptor modulators and methods of use thereof
US6995284B2 (en) * 2000-08-24 2006-02-07 The University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
US7759520B2 (en) * 1996-11-27 2010-07-20 University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
US6071957A (en) * 1996-11-27 2000-06-06 The University Of Tennessee Research Corporation Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer
US7518013B2 (en) * 2000-08-24 2009-04-14 University Of Tennessee Research Foundation Selective androgen receptor modulators
WO1998053826A1 (en) * 1997-05-30 1998-12-03 The University Of Tennessee Research Corporation Non-steroidal agonist compounds and their use in male hormone therapy
WO1998055153A1 (en) * 1997-06-04 1998-12-10 The University Of Tennessee Research Corporation Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging
US20040186185A1 (en) * 1998-05-07 2004-09-23 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
US20070173546A1 (en) * 2000-08-24 2007-07-26 Dalton James T Selective androgen receptor modulators and method of use thereof
US7622503B2 (en) * 2000-08-24 2009-11-24 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US8445534B2 (en) 2000-08-24 2013-05-21 University Of Tennessee Research Foundation Treating androgen decline in aging male (ADAM)-associated conditions with SARMs
PT1491524E (pt) 2000-08-24 2009-04-16 Univ Tennessee Res Foundation Moduladores selectivos do receptor androgénico e processos para a sua utilização
US7919647B2 (en) * 2000-08-24 2011-04-05 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US20040260108A1 (en) * 2001-06-25 2004-12-23 Dalton James T. Metabolites of selective androgen receptor modulators and methods of use thereof
US7026500B2 (en) * 2000-08-24 2006-04-11 University Of Tennessee Research Foundation Halogenated selective androgen receptor modulators and methods of use thereof
US6838484B2 (en) * 2000-08-24 2005-01-04 University Of Tennessee Research Foundation Formulations comprising selective androgen receptor modulators
IL154425A0 (en) 2000-08-24 2003-09-17 Univ Tennessee Res H Corp Selective androgen receptor modulators and methods of use thereof
US7645898B2 (en) * 2000-08-24 2010-01-12 University Of Tennessee Research Foundation Selective androgen receptor modulators and method of use thereof
US6998500B2 (en) * 2000-08-24 2006-02-14 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US7855229B2 (en) * 2000-08-24 2010-12-21 University Of Tennessee Research Foundation Treating wasting disorders with selective androgen receptor modulators
US8008348B2 (en) * 2001-12-06 2011-08-30 University Of Tennessee Research Foundation Treating muscle wasting with selective androgen receptor modulators
US7102026B2 (en) * 2001-06-13 2006-09-05 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Process for preparing and isolating rac-bicalutamide and its intermediates
US20060287282A1 (en) * 2001-06-25 2006-12-21 Steiner Mitchell S Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof
US7015253B2 (en) * 2001-07-10 2006-03-21 American Medical Systems, Inc. Regimen for treating prostate tissue and surgical kit for use in the regimen
US8853266B2 (en) * 2001-12-06 2014-10-07 University Of Tennessee Research Foundation Selective androgen receptor modulators for treating diabetes
US20070161608A1 (en) * 2001-12-06 2007-07-12 Dalton James T Selective androgen receptor modulators for treating muscle wasting
PT1463497E (pt) * 2001-12-06 2011-12-20 Gtx Inc Tratamento do desgaste muscular com moduladores selectivos do receptor de androgénios
KR101032661B1 (ko) * 2002-02-07 2011-05-06 유니버시티 오브 테네시 리서치 파운데이션 선택적 안드로겐 수용체 조절자를 이용한 양성 전립선과형성증의 치료 방법
EP1487458B1 (en) * 2002-02-28 2011-11-16 University Of Tennessee Research Foundation Multi-substituted selective androgen receptor modulators and methods of use thereof
US7772433B2 (en) * 2002-02-28 2010-08-10 University Of Tennessee Research Foundation SARMS and method of use thereof
WO2003074471A1 (en) * 2002-02-28 2003-09-12 University Of Tennessee Research Foundation Haloacetamide and azide substituted compounds and methods of use thereof
AU2003217304A1 (en) * 2002-02-28 2003-09-16 The University Of Tennessee Research Corporation Radiolabeled selective androgen receptor modulators and their use in prostate cancer imaging and therapy
US7803970B2 (en) * 2002-02-28 2010-09-28 University Of Tennessee Research Foundation Multi-substitued selective androgen receptor modulators and methods of use thereof
US7022870B2 (en) * 2002-06-17 2006-04-04 University Of Tennessee Research Foundation N-bridged selective androgen receptor modulators and methods of use thereof
US7741371B2 (en) * 2002-06-17 2010-06-22 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
JP4449746B2 (ja) 2002-07-12 2010-04-14 アステラス製薬株式会社 Ｎ−フェニル−（２ｒ，５ｓ）ジメチルピペラジン誘導体
JP2006505563A (ja) * 2002-10-15 2006-02-16 ジーティーエックス・インコーポレイテッド 選択的アンドロゲン受容体調節剤による肥満治療
US20040197928A1 (en) * 2002-10-15 2004-10-07 Dalton James T. Method for detecting selective androgen receptor modulators
JP2006506369A (ja) * 2002-10-15 2006-02-23 ユニバーシティ・オブ・テネシー・リサーチ・ファウンデーション メチレン架橋選択的アンドロゲン受容体調節剤及びその使用方法
US20060276539A1 (en) * 2002-10-16 2006-12-07 Dalton James T Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS
EP1558233A2 (en) * 2002-10-16 2005-08-03 GTX, Inc. Treating androgen decline in aging male (adam)-associated conditions with sarms
US20040087810A1 (en) * 2002-10-23 2004-05-06 Dalton James T. Irreversible selective androgen receptor modulators and methods of use thereof
US8309603B2 (en) 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
US20040167103A1 (en) * 2003-02-24 2004-08-26 Dalton James T. Haloacetamide and azide substituted compounds and methods of use thereof
CN1805921A (zh) * 2003-12-16 2006-07-19 Gtx公司 选择性雄激素受体调节剂的前药及其使用方法
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US20110237664A1 (en) * 2004-06-07 2011-09-29 Dalton James T Selective androgen receptor modulators for treating diabetes
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US20060258628A1 (en) * 2004-07-20 2006-11-16 Steiner Mitchell S Compositions comprising 5-alpha reductase inhibitors, and SARMs and methods of use thereof
PT2054049E (pt) 2006-08-24 2016-06-02 Univ Tennessee Res Found Acilanilidas substituídas e métodos de utilização das mesmas
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
WO2008083407A1 (en) 2007-01-02 2008-07-10 Aquabeam Llc Minimally invasive methods and devices for the treatment of prostate diseases
US9232959B2 (en) 2007-01-02 2016-01-12 Aquabeam, Llc Multi fluid tissue resection methods and devices
US20080245375A1 (en) * 2007-04-05 2008-10-09 Medtronic Vascular, Inc. Benign Prostatic Hyperplasia Treatments
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
JP5506702B2 (ja) 2008-03-06 2014-05-28 アクアビーム エルエルシー 流体流れ内を伝達される光学エネルギーによる組織切除および焼灼
US10524822B2 (en) 2009-03-06 2020-01-07 Procept Biorobotics Corporation Image-guided eye surgery apparatus
US9848904B2 (en) 2009-03-06 2017-12-26 Procept Biorobotics Corporation Tissue resection and treatment with shedding pulses
WO2012109387A1 (en) 2011-02-08 2012-08-16 Halozyme, Inc. Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia
CN108606773B (zh) 2012-02-29 2020-08-11 普罗赛普特生物机器人公司 自动化图像引导的组织切除和处理
US10314807B2 (en) 2012-07-13 2019-06-11 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
PT2872482T (pt) 2012-07-13 2020-09-22 Oncternal Therapeutics Inc Método de tratamento de cancro de mama com modulador seletivo do recetor de andrógeno (sarm)
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9969683B2 (en) 2012-07-13 2018-05-15 Gtx, Inc. Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10987334B2 (en) 2012-07-13 2021-04-27 University Of Tennessee Research Foundation Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
JP6461971B2 (ja) 2013-09-06 2019-01-30 プロセプト バイオロボティクス コーポレイション 飛散パルスを用いた組織切除および処置
JP6651471B2 (ja) 2014-06-30 2020-02-19 プロセプト バイオロボティクス コーポレイション 流体ジェット組織アブレーションおよび冷凝固（ａｑｕａｂｌａｔｉｏｎ）方法および装置
BR112017004431B1 (pt) 2014-09-05 2022-11-01 Procept Biorobotics Corporation Aparelho para tratar um paciente

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
FR1268684A (fr) * 1960-08-08 1961-08-04 Basf Ag Procédé pour la production d'amides d'acide beta-hydroxypropionique nu-substituéset de leurs esters avec des acides forts, oxygénés
DE1173082B (de) * 1962-06-06 1964-07-02 Bayer Ag Verfahren zur Herstellung von N-mono-substituierten ª‡-Hydroxycarbonsaeureamiden
US3197503A (en) * 1962-12-14 1965-07-27 Monsanto Co N-(aryl) oxamic acid chlorides
US3201466A (en) * 1963-03-08 1965-08-17 Gulf Oil Corp Substituted cyclopropanecarboxanilide herbicides
NL123536C ( ) * 1963-07-09
DE1189312B (de) * 1963-12-06 1965-03-18 Schering Ag Mittel mit selektiver herbizider Wirkung
GB1065801A (en) * 1964-02-19 1967-04-19 Nippon Soda Co N-substituted fluoroacetamides and their use as insecticides
US3418345A (en) * 1965-10-18 1968-12-24 Monsanto Co Halonitroanilides
US3426049A (en) * 1965-10-18 1969-02-04 Monsanto Co Nitrotrifluoromethylanilides
US3462486A (en) * 1966-12-28 1969-08-19 Gulf Oil Corp Method for preparing 3',4'-dichloro-cyclopropanecarboxanilide
US3608087A (en) * 1968-06-21 1971-09-21 Merck & Co Inc Feed compositions
US3723442A (en) * 1970-12-31 1973-03-27 Yoshitomi Pharmaceutical 3-oxo-1-oxa-4,8-diazaspiro(4.5)decanes
US3720686A (en) * 1971-04-01 1973-03-13 Squibb & Sons Inc Mercaptobenzimidazole derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003619A2 (en) * 1978-01-09 1979-08-22 Shell Internationale Researchmaatschappij B.V. Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them
EP0003619A3 (en) * 1978-01-09 1979-09-05 Shell Internationale Research Maatschappij B.V. Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them
US8552061B2 (en) 2007-05-03 2013-10-08 Yale University Locally active “soft” antiandrogens

Also Published As

Publication number Publication date
DE2357757A1 (de) 1974-06-06
IE38530B1 (en) 1978-03-29
IL43664A0 (en) 1974-03-14
DD110856A5 ( ) 1975-01-12
IE38530L (en) 1974-05-24
US3875229A (en) 1975-04-01
BG21392A3 ( ) 1976-05-20
JPS4981332A ( ) 1974-08-06
AU6270573A (en) 1975-05-22
FR2207712A1 ( ) 1974-06-21
ES420688A1 (es) 1976-09-01
NL7315903A ( ) 1974-05-28
HU169277B ( ) 1976-10-28
FR2207712B1 ( ) 1976-12-03

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee