GB1440742A - 2,3,4,5-tetrahydro-4-phenyl-1h-1,4-benzodiazepine-1-carboximi damide and related compounds - Google Patents
2,3,4,5-tetrahydro-4-phenyl-1h-1,4-benzodiazepine-1-carboximi damide and related compoundsInfo
- Publication number
- GB1440742A GB1440742A GB411575A GB411575A GB1440742A GB 1440742 A GB1440742 A GB 1440742A GB 411575 A GB411575 A GB 411575A GB 411575 A GB411575 A GB 411575A GB 1440742 A GB1440742 A GB 1440742A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- benzodiazepine
- tetrahydro
- carboximi
- damide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical group 0.000 abstract 3
- YNWPBNWQAJYCKF-UHFFFAOYSA-N 4-phenyl-1,2,3,5-tetrahydro-1,4-benzodiazepine Chemical compound C1(=CC=CC=C1)N1CCNC2=C(C1)C=CC=C2 YNWPBNWQAJYCKF-UHFFFAOYSA-N 0.000 abstract 1
- OUUMEHCZPBHNBK-UHFFFAOYSA-N 4-phenyl-1,3-dihydro-1,4-benzodiazepine-2,5-dione Chemical compound O=C1C2=CC=CC=C2NC(=O)CN1C1=CC=CC=C1 OUUMEHCZPBHNBK-UHFFFAOYSA-N 0.000 abstract 1
- YGZDFCLVLCBQOZ-UHFFFAOYSA-N 4-phenyl-3,5-dihydro-2h-1,4-benzodiazepine-1-carboximidamide Chemical class C1C2=CC=CC=C2N(C(=N)N)CCN1C1=CC=CC=C1 YGZDFCLVLCBQOZ-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US469172A US3869447A (en) | 1974-05-13 | 1974-05-13 | 2,3,4,5-Tetrahydro-4-phenyl-1H-1,4-benzodiazepine-1-carboximidamide and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1440742A true GB1440742A (en) | 1976-06-23 |
Family
ID=23862727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB411575A Expired GB1440742A (en) | 1974-05-13 | 1975-01-30 | 2,3,4,5-tetrahydro-4-phenyl-1h-1,4-benzodiazepine-1-carboximi damide and related compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3869447A (enExample) |
| JP (1) | JPS50149693A (enExample) |
| CA (1) | CA1039281A (enExample) |
| DE (1) | DE2503450A1 (enExample) |
| FR (1) | FR2270883B1 (enExample) |
| GB (1) | GB1440742A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0087850A1 (en) * | 1982-01-04 | 1983-09-07 | The Upjohn Company | Benzodiazepines for anti-hypertensive use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3481921A (en) * | 1965-10-22 | 1969-12-02 | Hoffmann La Roche | Benzodiazepines |
| US3812103A (en) * | 1967-04-11 | 1974-05-21 | Hoffmann La Roche | 2,3-dihydro-1,4-benzodiazepines |
-
1974
- 1974-05-13 US US469172A patent/US3869447A/en not_active Expired - Lifetime
-
1975
- 1975-01-27 CA CA000218682A patent/CA1039281A/en not_active Expired
- 1975-01-28 DE DE19752503450 patent/DE2503450A1/de active Pending
- 1975-01-30 GB GB411575A patent/GB1440742A/en not_active Expired
- 1975-02-01 JP JP50013941A patent/JPS50149693A/ja active Pending
- 1975-02-04 FR FR7503450A patent/FR2270883B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3869447A (en) | 1975-03-04 |
| FR2270883B1 (enExample) | 1978-07-21 |
| CA1039281A (en) | 1978-09-26 |
| FR2270883A1 (enExample) | 1975-12-12 |
| DE2503450A1 (de) | 1975-11-27 |
| JPS50149693A (enExample) | 1975-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |