GB1440361A - 11-deoxyprostaglandins of the e and f series and the preparation thereof - Google Patents

11-deoxyprostaglandins of the e and f series and the preparation thereof

Info

Publication number
GB1440361A
GB1440361A GB2583673A GB2583673A GB1440361A GB 1440361 A GB1440361 A GB 1440361A GB 2583673 A GB2583673 A GB 2583673A GB 2583673 A GB2583673 A GB 2583673A GB 1440361 A GB1440361 A GB 1440361A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compounds
vinylene
mercapto
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2583673A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/274,559 external-priority patent/US4141914A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB1440361A publication Critical patent/GB1440361A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB2583673A 1972-07-24 1973-05-30 11-deoxyprostaglandins of the e and f series and the preparation thereof Expired GB1440361A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/274,559 US4141914A (en) 1972-07-24 1972-07-24 Novel 11-deoxy-11-substituted prostaglandins of the E and F series
US30772172A 1972-11-17 1972-11-17

Publications (1)

Publication Number Publication Date
GB1440361A true GB1440361A (en) 1976-06-23

Family

ID=26956900

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2583673A Expired GB1440361A (en) 1972-07-24 1973-05-30 11-deoxyprostaglandins of the e and f series and the preparation thereof

Country Status (5)

Country Link
JP (1) JPS4985052A (enrdf_load_stackoverflow)
DE (1) DE2330905A1 (enrdf_load_stackoverflow)
FR (1) FR2193613B1 (enrdf_load_stackoverflow)
GB (1) GB1440361A (enrdf_load_stackoverflow)
NL (1) NL7308633A (enrdf_load_stackoverflow)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218565A (en) * 1972-07-24 1980-08-19 American Cyanamid Company Novel 11-deoxy-11-substituted prostaglandins of the E and F series
US4241221A (en) * 1972-07-24 1980-12-23 American Cyanamid Company Novel 11-deoxy-substituted prostaglandins of the E and F series
US4053467A (en) * 1974-07-03 1977-10-11 American Home Products Corporation Prostaglandin derivatives
DE2629834A1 (de) 1976-06-30 1978-01-12 Schering Ag Neue prostansaeurederivate und verfahren zu ihrer herstellung
US4325970A (en) * 1980-10-09 1982-04-20 Hoffmann-La Roche Inc. 15-Acetyl-prostaglandins
US4403100A (en) * 1981-10-30 1983-09-06 The Upjohn Company (11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins
KR100224951B1 (ko) * 1990-03-08 1999-10-15 시오노 요시히코 15-데옥시프로스타글란딘유도체
US5292754A (en) * 1990-03-08 1994-03-08 Shionogi & Co., Ltd. Treatment for hypertension or glaucoma in eyes

Also Published As

Publication number Publication date
FR2193613A1 (enrdf_load_stackoverflow) 1974-02-22
FR2193613B1 (enrdf_load_stackoverflow) 1976-12-24
NL7308633A (enrdf_load_stackoverflow) 1974-01-28
DE2330905A1 (de) 1974-02-07
JPS4985052A (enrdf_load_stackoverflow) 1974-08-15
AU5681373A (en) 1974-12-12

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee