GB1438987A - Method of preparing n1-2-1-furanidyl- and n1-2-1-pyranidyl-uracils - Google Patents
Method of preparing n1-2-1-furanidyl- and n1-2-1-pyranidyl-uracilsInfo
- Publication number
- GB1438987A GB1438987A GB5320873A GB5320873A GB1438987A GB 1438987 A GB1438987 A GB 1438987A GB 5320873 A GB5320873 A GB 5320873A GB 5320873 A GB5320873 A GB 5320873A GB 1438987 A GB1438987 A GB 1438987A
- Authority
- GB
- United Kingdom
- Prior art keywords
- uracils
- pyranidyl
- furanidyl
- formula
- nov
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Furanidyl Chemical group 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 229910003902 SiCl 4 Inorganic materials 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000004292 cyclic ethers Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1848519 | 1972-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1438987A true GB1438987A (en) | 1976-06-09 |
Family
ID=20532678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5320873A Expired GB1438987A (en) | 1972-11-20 | 1973-11-16 | Method of preparing n1-2-1-furanidyl- and n1-2-1-pyranidyl-uracils |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3912734A (enExample) |
| BE (1) | BE807556A (enExample) |
| CA (1) | CA999863A (enExample) |
| CH (1) | CH586696A5 (enExample) |
| DE (1) | DE2357847A1 (enExample) |
| FR (1) | FR2207138B1 (enExample) |
| GB (1) | GB1438987A (enExample) |
| NL (1) | NL7315712A (enExample) |
| SE (1) | SE412232B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5175079A (en) * | 1974-09-13 | 1976-06-29 | Mitsui Seiyaku Kogyo Kk | 11 * 22 tetorahidorofuriru * 55 furuororashiru no seizoho |
| US4039546A (en) * | 1975-04-28 | 1977-08-02 | Solomon Aronovich Giller | Method of preparing N1 -(2'-furanidyl)-5-substituted uracils |
| US4124765A (en) * | 1975-05-13 | 1978-11-07 | Ono Pharmaceutical Co., Ltd. | 5-Fluorouracil derivatives |
| DE2648239C3 (de) * | 1975-10-24 | 1981-11-12 | Rikagaku Kenkyusho, Wako, Saitama | Di-(trialkylstannyl)-pyrimidinderivate, Verfahren zu ihrer Herstellung und Verfahren zu ihrer Weiterverarbeitung zu nucleosidartigen Pyrimidinderivaten |
| DE2650918C2 (de) * | 1975-11-10 | 1983-06-09 | Asahi Kasei Kogyo K.K., Osaka | Verfahren zur Herstellung von N↓1↓-(2-Tetrahydrofuranyl)-5-fluor-uracil |
| JPS5259174A (en) * | 1975-11-10 | 1977-05-16 | Asahi Chem Ind Co Ltd | Preparation of n-substituted uracil compounds |
| IE45046B1 (en) * | 1975-11-28 | 1982-06-16 | Takeda Chemical Industries Ltd | Method of producing 5-fluorouracil derivatives |
| US4324895A (en) * | 1975-12-04 | 1982-04-13 | Rikagaku Kenkyusho | Novel process for producing pyrimidine nucleosides and novel pyrimidine nucleosides obtained thereby |
| IL50671A (en) * | 1976-10-12 | 1980-03-31 | Abic Ltd | Process for the preparation of n1-(2'furanidyl)-5-fluoro-uracil and bis-2'-furanidylether as intermediate therefor |
| US4125719A (en) * | 1977-08-01 | 1978-11-14 | Merck & Co., Inc. | 1,3,5-S-Hexahydrotrisubstituted triazines |
| EP0059307A1 (de) | 1981-02-26 | 1982-09-08 | Grünenthal GmbH | Verfahren zur Herstellung von 2-Oxabicyclo(3.3.0)octanderivaten und danach erhältliche Produkte |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3352849A (en) * | 1965-10-24 | 1967-11-14 | Merck & Co Inc | 6-aza-2'-deoxyuridines |
-
1973
- 1973-06-01 US US366215A patent/US3912734A/en not_active Expired - Lifetime
- 1973-11-14 CA CA185,741A patent/CA999863A/en not_active Expired
- 1973-11-16 GB GB5320873A patent/GB1438987A/en not_active Expired
- 1973-11-16 CH CH1614673A patent/CH586696A5/xx not_active IP Right Cessation
- 1973-11-16 NL NL7315712A patent/NL7315712A/xx unknown
- 1973-11-19 SE SE7315630A patent/SE412232B/xx unknown
- 1973-11-20 FR FR7341199A patent/FR2207138B1/fr not_active Expired
- 1973-11-20 DE DE2357847A patent/DE2357847A1/de active Pending
- 1973-11-20 BE BE137955A patent/BE807556A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7315712A (enExample) | 1974-05-22 |
| US3912734A (en) | 1975-10-14 |
| SE412232B (sv) | 1980-02-25 |
| FR2207138A1 (enExample) | 1974-06-14 |
| DE2357847A1 (de) | 1974-06-20 |
| BE807556A (fr) | 1974-05-20 |
| CA999863A (en) | 1976-11-16 |
| CH586696A5 (enExample) | 1977-04-15 |
| FR2207138B1 (enExample) | 1976-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |