GB1437781A - Pyridine derivatives having hypoglycaemic activity - Google Patents
Pyridine derivatives having hypoglycaemic activityInfo
- Publication number
- GB1437781A GB1437781A GB1528072A GB1528072A GB1437781A GB 1437781 A GB1437781 A GB 1437781A GB 1528072 A GB1528072 A GB 1528072A GB 1528072 A GB1528072 A GB 1528072A GB 1437781 A GB1437781 A GB 1437781A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- carboxylic acid
- formula
- alk
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000002218 hypoglycaemic effect Effects 0.000 title abstract 2
- 150000003222 pyridines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000002843 carboxylic acid group Chemical group 0.000 abstract 4
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- PCLIMKBDDGJMGD-UHFFFAOYSA-N N-bromosuccinimide Chemical compound BrN1C(=O)CCC1=O PCLIMKBDDGJMGD-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- NJWIMFZLESWFIM-UHFFFAOYSA-N 2-(chloromethyl)pyridine Chemical compound ClCC1=CC=CC=N1 NJWIMFZLESWFIM-UHFFFAOYSA-N 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- -1 5-ethylpyrid-2-yl Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- TWQLMAJROCNXEA-UHFFFAOYSA-N ethyl 4-(bromomethyl)benzoate Chemical compound CCOC(=O)C1=CC=C(CBr)C=C1 TWQLMAJROCNXEA-UHFFFAOYSA-N 0.000 abstract 1
- NWPWRAWAUYIELB-UHFFFAOYSA-N ethyl 4-methylbenzoate Chemical compound CCOC(=O)C1=CC=C(C)C=C1 NWPWRAWAUYIELB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- SHNUBALDGXWUJI-UHFFFAOYSA-N pyridin-2-ylmethanol Chemical compound OCC1=CC=CC=N1 SHNUBALDGXWUJI-UHFFFAOYSA-N 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1528072A GB1437781A (en) | 1972-04-04 | 1972-04-04 | Pyridine derivatives having hypoglycaemic activity |
| AR247376A AR208269A1 (es) | 1972-04-04 | 1973-01-01 | Un procedimiento para la preparacion de derivados de piridilifenil-oxialcanos y sus sales de adicion de acido |
| IE426/73A IE37412B1 (en) | 1972-04-04 | 1973-03-15 | Pyridine derivatives having hypoglycaemic activity |
| ZA731853A ZA731853B (en) | 1972-04-04 | 1973-03-16 | Biologically active compounds |
| IL41825A IL41825A (en) | 1972-04-04 | 1973-03-19 | Pyridine derivatives their preparation and pharmaceutical compositions containing them |
| HURO717A HU165731B (enExample) | 1972-04-04 | 1973-03-30 | |
| AT286773A AT339301B (de) | 1972-04-04 | 1973-04-02 | Verfahren zur herstellung von neuen pyridinderivaten und deren saureadditionssalzen |
| JP48038610A JPS49100091A (enExample) | 1972-04-04 | 1973-04-03 | |
| CS7300002387A CS183689B2 (en) | 1972-04-04 | 1973-04-03 | Process for preparing pyridylphenoxyalkane derivatives |
| NL7304610A NL7304610A (enExample) | 1972-04-04 | 1973-04-03 | |
| BE129595A BE797715A (fr) | 1972-04-04 | 1973-04-03 | Composes a activite biologique |
| RO7300074369A RO62274A (fr) | 1972-04-04 | 1973-04-03 | Procede pour la preparation des derives de pyridine |
| ES413279A ES413279A1 (es) | 1972-04-04 | 1973-04-03 | Un procedimiento para la preparacion de compuestos biologi-camente activos en el tratamiento de la hipoglicemia. |
| CA167,818A CA999868A (en) | 1972-04-04 | 1973-04-03 | Biologically active compounds |
| RO7300083382A RO63069A (fr) | 1972-04-04 | 1973-04-03 | Procede pour la preparation des derives pyridine |
| BG023170A BG20352A3 (bg) | 1972-04-04 | 1973-04-04 | Метод за получаване на пиридил-фенил оксиалкани |
| CH482673A CH576961A5 (enExample) | 1972-04-04 | 1973-04-04 | |
| DD169942A DD106834A5 (enExample) | 1972-04-04 | 1973-04-04 | |
| FR7312133A FR2182933B1 (enExample) | 1972-04-04 | 1973-04-04 | |
| DE2316881A DE2316881A1 (de) | 1972-04-04 | 1973-04-04 | Biologisch aktive verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate |
| PL1973161704A PL96043B1 (pl) | 1972-04-04 | 1973-04-04 | Sposob wytwarzania pirydylofenylooksyalkanow |
| US05/586,817 US4053607A (en) | 1972-04-04 | 1975-06-13 | Aryloxypyridine for treating hyperglycaemia |
| US05/626,720 US4036844A (en) | 1972-04-04 | 1975-10-29 | Aryloxypyridines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1528072A GB1437781A (en) | 1972-04-04 | 1972-04-04 | Pyridine derivatives having hypoglycaemic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1437781A true GB1437781A (en) | 1976-06-03 |
Family
ID=10056262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1528072A Expired GB1437781A (en) | 1972-04-04 | 1972-04-04 | Pyridine derivatives having hypoglycaemic activity |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS49100091A (enExample) |
| AR (1) | AR208269A1 (enExample) |
| AT (1) | AT339301B (enExample) |
| BE (1) | BE797715A (enExample) |
| BG (1) | BG20352A3 (enExample) |
| CA (1) | CA999868A (enExample) |
| CH (1) | CH576961A5 (enExample) |
| CS (1) | CS183689B2 (enExample) |
| DD (1) | DD106834A5 (enExample) |
| DE (1) | DE2316881A1 (enExample) |
| ES (1) | ES413279A1 (enExample) |
| FR (1) | FR2182933B1 (enExample) |
| GB (1) | GB1437781A (enExample) |
| HU (1) | HU165731B (enExample) |
| IE (1) | IE37412B1 (enExample) |
| IL (1) | IL41825A (enExample) |
| NL (1) | NL7304610A (enExample) |
| PL (1) | PL96043B1 (enExample) |
| RO (2) | RO63069A (enExample) |
| ZA (1) | ZA731853B (enExample) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409227A (en) | 1979-08-09 | 1983-10-11 | The Dow Chemical Co. | 4-(((Heterocyclo)thio)methyl)benzoic acids, esters and amides and their pharmaceutical use |
| US5324533A (en) * | 1991-07-03 | 1994-06-28 | Van Den Bergh Foods Co., Division Of Conopco Inc. | Chocolate compositions |
| US5385744A (en) * | 1991-07-03 | 1995-01-31 | Van Den Bergh Foods Co., Division Of Conopco Inc. | Chocolate-encapsulated fillings |
| WO2005094810A3 (en) * | 2004-03-05 | 2006-01-12 | Karobio Ab | Novel pharmaceutical compositions |
| EP2514745A1 (en) * | 2008-12-18 | 2012-10-24 | Metabolex Inc. | GPR120 receptor agonists and uses thereof |
| WO2017174879A1 (en) * | 2016-04-06 | 2017-10-12 | University Of Oulu | Compounds for use in the treatment of cancer |
| US10178875B2 (en) | 2013-07-01 | 2019-01-15 | Givaudan S.A. | Methods of modifying or imparting taste using organic compounds |
| US20190389801A1 (en) * | 2015-04-15 | 2019-12-26 | T. Hasegawa Co., Ltd. | Flavor modulator having pyridine derivative or salt thereof as active ingredient |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5453433A (en) * | 1994-05-13 | 1995-09-26 | Sterling Winthrop Inc. | Thiadiazoles and antipicornaviral compositions |
| AU2381497A (en) * | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
| US6043247A (en) * | 1996-04-19 | 2000-03-28 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
| US6329372B1 (en) | 1998-01-27 | 2001-12-11 | Celltech Therapeutics Limited | Phenylalanine derivatives |
| ES2226413T3 (es) | 1998-02-26 | 2005-03-16 | Celltech Therapeutics Limited | Derivados de fenilalanina como inhibidores de alfa-4 integrinas. |
| GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| GB9811159D0 (en) | 1998-05-22 | 1998-07-22 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9811969D0 (en) | 1998-06-03 | 1998-07-29 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9812088D0 (en) | 1998-06-05 | 1998-08-05 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9814414D0 (en) * | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9821222D0 (en) | 1998-09-30 | 1998-11-25 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9825652D0 (en) | 1998-11-23 | 1999-01-13 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
| US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
| US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
| US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
| AU2001248553A1 (en) | 2000-04-17 | 2001-10-30 | Celltech R And D Limited | Enamine derivatives as cell adhesion molecules |
| US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
| US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
| AU2001267753A1 (en) | 2000-07-07 | 2002-01-21 | Celltech R And D Limited | Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists |
| JP2004505110A (ja) | 2000-08-02 | 2004-02-19 | セルテック アール アンド ディ リミテッド | ３位置換イソキノリン−１−イル誘導体 |
| US7101910B2 (en) * | 2001-06-12 | 2006-09-05 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| TWI490214B (zh) * | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
-
1972
- 1972-04-04 GB GB1528072A patent/GB1437781A/en not_active Expired
-
1973
- 1973-01-01 AR AR247376A patent/AR208269A1/es active
- 1973-03-15 IE IE426/73A patent/IE37412B1/xx unknown
- 1973-03-16 ZA ZA731853A patent/ZA731853B/xx unknown
- 1973-03-19 IL IL41825A patent/IL41825A/en unknown
- 1973-03-30 HU HURO717A patent/HU165731B/hu unknown
- 1973-04-02 AT AT286773A patent/AT339301B/de not_active IP Right Cessation
- 1973-04-03 CA CA167,818A patent/CA999868A/en not_active Expired
- 1973-04-03 CS CS7300002387A patent/CS183689B2/cs unknown
- 1973-04-03 ES ES413279A patent/ES413279A1/es not_active Expired
- 1973-04-03 JP JP48038610A patent/JPS49100091A/ja active Pending
- 1973-04-03 RO RO7300083382A patent/RO63069A/ro unknown
- 1973-04-03 BE BE129595A patent/BE797715A/xx unknown
- 1973-04-03 RO RO7300074369A patent/RO62274A/ro unknown
- 1973-04-03 NL NL7304610A patent/NL7304610A/xx not_active Application Discontinuation
- 1973-04-04 FR FR7312133A patent/FR2182933B1/fr not_active Expired
- 1973-04-04 BG BG023170A patent/BG20352A3/xx unknown
- 1973-04-04 DD DD169942A patent/DD106834A5/xx unknown
- 1973-04-04 PL PL1973161704A patent/PL96043B1/pl unknown
- 1973-04-04 CH CH482673A patent/CH576961A5/xx not_active IP Right Cessation
- 1973-04-04 DE DE2316881A patent/DE2316881A1/de active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409227A (en) | 1979-08-09 | 1983-10-11 | The Dow Chemical Co. | 4-(((Heterocyclo)thio)methyl)benzoic acids, esters and amides and their pharmaceutical use |
| US5324533A (en) * | 1991-07-03 | 1994-06-28 | Van Den Bergh Foods Co., Division Of Conopco Inc. | Chocolate compositions |
| US5385744A (en) * | 1991-07-03 | 1995-01-31 | Van Den Bergh Foods Co., Division Of Conopco Inc. | Chocolate-encapsulated fillings |
| WO2005094810A3 (en) * | 2004-03-05 | 2006-01-12 | Karobio Ab | Novel pharmaceutical compositions |
| EP2514745A1 (en) * | 2008-12-18 | 2012-10-24 | Metabolex Inc. | GPR120 receptor agonists and uses thereof |
| US10178875B2 (en) | 2013-07-01 | 2019-01-15 | Givaudan S.A. | Methods of modifying or imparting taste using organic compounds |
| US20190389801A1 (en) * | 2015-04-15 | 2019-12-26 | T. Hasegawa Co., Ltd. | Flavor modulator having pyridine derivative or salt thereof as active ingredient |
| US10882823B2 (en) * | 2015-04-15 | 2021-01-05 | T. Hasegawa Co., Ltd. | Flavor modulator having pyridine derivative or salt thereof as active ingredient |
| US10894772B2 (en) | 2015-04-15 | 2021-01-19 | T. Hasegawa Co., Ltd. | Flavor modulator having pyridine derivative or salt thereof as active ingredient |
| WO2017174879A1 (en) * | 2016-04-06 | 2017-10-12 | University Of Oulu | Compounds for use in the treatment of cancer |
| US11096909B2 (en) | 2016-04-06 | 2021-08-24 | University Of Oulu | Compounds for use in the treatment of cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| RO62274A (fr) | 1977-12-15 |
| PL96043B1 (pl) | 1977-11-30 |
| FR2182933B1 (enExample) | 1976-05-14 |
| AT339301B (de) | 1977-10-10 |
| ATA286773A (de) | 1977-02-15 |
| NL7304610A (enExample) | 1973-10-08 |
| CS183689B2 (en) | 1978-07-31 |
| IL41825A (en) | 1977-03-31 |
| FR2182933A1 (enExample) | 1973-12-14 |
| IL41825A0 (en) | 1973-05-31 |
| HU165731B (enExample) | 1974-10-28 |
| BG20352A3 (bg) | 1975-11-05 |
| IE37412B1 (en) | 1977-07-20 |
| IE37412L (en) | 1973-10-04 |
| DD106834A5 (enExample) | 1974-07-05 |
| ES413279A1 (es) | 1976-01-01 |
| AR208269A1 (es) | 1976-12-20 |
| JPS49100091A (enExample) | 1974-09-20 |
| ZA731853B (en) | 1974-01-30 |
| BE797715A (fr) | 1973-10-03 |
| CH576961A5 (enExample) | 1976-06-30 |
| CA999868A (en) | 1976-11-16 |
| DE2316881A1 (de) | 1973-10-11 |
| RO63069A (fr) | 1978-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |