GB1435757A - Cyclopentane derivatives - Google Patents
Cyclopentane derivativesInfo
- Publication number
- GB1435757A GB1435757A GB3303073A GB3303073A GB1435757A GB 1435757 A GB1435757 A GB 1435757A GB 3303073 A GB3303073 A GB 3303073A GB 3303073 A GB3303073 A GB 3303073A GB 1435757 A GB1435757 A GB 1435757A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trans
- trimethylsilyloxy
- prostadienoate
- methoxyimino
- chlorophenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000001511 cyclopentyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 title 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 2
- -1 trimethylsilyloxy Chemical group 0.000 abstract 2
- 125000004199 4-trifluoromethylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C(F)(F)F 0.000 abstract 1
- 239000007983 Tris buffer Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1435757 Silylated prostaglandins IMPERIAL CHEMICAL INDUSTRIES Ltd 10 June 1974 [11 July 1973] 33030/73 Heading C3S [Also in Divisions C2 and A5] Trimethylsilyl 16 - (3 - chlorophenoxy)- 9α,11α,15 - tris(trimethylsilyloxy) - 17,18,19,20- tetranor - 5 - trans, 13 - trans - prostadienoate, methyl 9 - methoxyimino - 15 - (4 - trifluoromethylphenyl) - 9α,15 - bis - (trimethylsilyloxy)- 16,17,18,19,20 - pentanor - 5 - trans,13 - transprostadienoate and trimethylsilyl 16-(4-chlorophenoxy) - 9 - methoxyimino - 16 - methyl- 11α,15 - bis - (trimethylsilyloxy) - 18,19,20- trinor - 5 - trans,13-trans - prostadienoate are prepared by standard methods.
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3303073A GB1435757A (en) | 1973-07-11 | 1973-07-11 | Cyclopentane derivatives |
IE1250/74A IE40235B1 (en) | 1973-07-11 | 1974-06-14 | Cyclopentane derivatives |
ZA00743855A ZA743855B (en) | 1973-07-11 | 1974-06-17 | Cyclopentane derivatives |
AU70386/74A AU492502B2 (en) | 1974-06-21 | Cyclopentane derivatives | |
IL45084A IL45084A0 (en) | 1973-07-11 | 1974-06-21 | Prostenoic acid derivatives |
ZM104/74A ZM10474A1 (en) | 1973-07-11 | 1974-06-25 | Cyclopentane derivatives |
CA203,924A CA1040195A (en) | 1973-07-11 | 1974-07-03 | Cyclopentane derivatives |
DK358974A DK358974A (en) | 1973-07-11 | 1974-07-04 | |
FI2095/74A FI209574A (en) | 1973-07-11 | 1974-07-08 | |
DD179813A DD114253A5 (en) | 1973-07-11 | 1974-07-09 | |
LU70488A LU70488A1 (en) | 1973-07-11 | 1974-07-09 | |
PL1974172572A PL95791B1 (en) | 1973-07-11 | 1974-07-09 | METHOD OF MAKING NEW DERIVATIVES OF CYCLOPENTANE |
SE7409074A SE7409074L (en) | 1973-07-11 | 1974-07-10 | CYCLOPENTAN DERIVATIVES AND THEY OF THEIR PREPARATION. |
FR7424018A FR2236492B1 (en) | 1973-07-11 | 1974-07-10 | |
NO742518A NO742518L (en) | 1973-07-11 | 1974-07-10 | |
BE146445A BE817513A (en) | 1973-07-11 | 1974-07-10 | CYCLOPENTANE DERIVATIVES |
NL7409311A NL7409311A (en) | 1973-07-11 | 1974-07-10 | PROCEDURE FOR THE PREPARATION OF NEW CYCLOPENT DERIVATIVES AND PREPARATIONS AND ARTICLES BASED THEREOF. |
JP49079679A JPS5058032A (en) | 1973-07-11 | 1974-07-11 | |
ES428182A ES428182A1 (en) | 1973-07-11 | 1974-07-11 | Cyclopentane derivatives |
DE2433393A DE2433393A1 (en) | 1973-07-11 | 1974-07-11 | CYCLOPENTAN DERIVATIVES |
EG271/74A EG11330A (en) | 1973-07-11 | 1974-07-13 | Process for preparation of cyclopentane derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3303073A GB1435757A (en) | 1973-07-11 | 1973-07-11 | Cyclopentane derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1435757A true GB1435757A (en) | 1976-05-12 |
Family
ID=10347594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3303073A Expired GB1435757A (en) | 1973-07-11 | 1973-07-11 | Cyclopentane derivatives |
Country Status (20)
Country | Link |
---|---|
JP (1) | JPS5058032A (en) |
BE (1) | BE817513A (en) |
CA (1) | CA1040195A (en) |
DD (1) | DD114253A5 (en) |
DE (1) | DE2433393A1 (en) |
DK (1) | DK358974A (en) |
EG (1) | EG11330A (en) |
ES (1) | ES428182A1 (en) |
FI (1) | FI209574A (en) |
FR (1) | FR2236492B1 (en) |
GB (1) | GB1435757A (en) |
IE (1) | IE40235B1 (en) |
IL (1) | IL45084A0 (en) |
LU (1) | LU70488A1 (en) |
NL (1) | NL7409311A (en) |
NO (1) | NO742518L (en) |
PL (1) | PL95791B1 (en) |
SE (1) | SE7409074L (en) |
ZA (1) | ZA743855B (en) |
ZM (1) | ZM10474A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992013836A1 (en) * | 1991-02-07 | 1992-08-20 | Allergan, Inc. | 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives |
-
1973
- 1973-07-11 GB GB3303073A patent/GB1435757A/en not_active Expired
-
1974
- 1974-06-14 IE IE1250/74A patent/IE40235B1/en unknown
- 1974-06-17 ZA ZA00743855A patent/ZA743855B/en unknown
- 1974-06-21 IL IL45084A patent/IL45084A0/en unknown
- 1974-06-25 ZM ZM104/74A patent/ZM10474A1/en unknown
- 1974-07-03 CA CA203,924A patent/CA1040195A/en not_active Expired
- 1974-07-04 DK DK358974A patent/DK358974A/da unknown
- 1974-07-08 FI FI2095/74A patent/FI209574A/fi unknown
- 1974-07-09 DD DD179813A patent/DD114253A5/xx unknown
- 1974-07-09 PL PL1974172572A patent/PL95791B1/en unknown
- 1974-07-09 LU LU70488A patent/LU70488A1/xx unknown
- 1974-07-10 NL NL7409311A patent/NL7409311A/en unknown
- 1974-07-10 FR FR7424018A patent/FR2236492B1/fr not_active Expired
- 1974-07-10 BE BE146445A patent/BE817513A/en unknown
- 1974-07-10 NO NO742518A patent/NO742518L/no unknown
- 1974-07-10 SE SE7409074A patent/SE7409074L/en not_active Application Discontinuation
- 1974-07-11 ES ES428182A patent/ES428182A1/en not_active Expired
- 1974-07-11 DE DE2433393A patent/DE2433393A1/en not_active Withdrawn
- 1974-07-11 JP JP49079679A patent/JPS5058032A/ja active Pending
- 1974-07-13 EG EG271/74A patent/EG11330A/en active
Also Published As
Publication number | Publication date |
---|---|
CA1040195A (en) | 1978-10-10 |
IE40235L (en) | 1975-01-11 |
BE817513A (en) | 1975-01-10 |
EG11330A (en) | 1977-02-28 |
DE2433393A1 (en) | 1975-01-30 |
ZA743855B (en) | 1975-06-25 |
DD114253A5 (en) | 1975-07-20 |
FR2236492B1 (en) | 1978-12-22 |
IL45084A0 (en) | 1974-10-22 |
AU7038674A (en) | 1976-01-08 |
JPS5058032A (en) | 1975-05-20 |
DK358974A (en) | 1975-03-03 |
FR2236492A1 (en) | 1975-02-07 |
ES428182A1 (en) | 1976-07-16 |
ZM10474A1 (en) | 1976-04-21 |
FI209574A (en) | 1975-01-12 |
LU70488A1 (en) | 1974-11-28 |
IE40235B1 (en) | 1979-04-11 |
SE7409074L (en) | 1975-01-13 |
NL7409311A (en) | 1975-01-14 |
NO742518L (en) | 1975-02-10 |
PL95791B1 (en) | 1977-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |