GB1403501A - Prostaglandins and the preparation thereof - Google Patents

Prostaglandins and the preparation thereof

Info

Publication number
GB1403501A
GB1403501A GB1542673A GB1542673A GB1403501A GB 1403501 A GB1403501 A GB 1403501A GB 1542673 A GB1542673 A GB 1542673A GB 1542673 A GB1542673 A GB 1542673A GB 1403501 A GB1403501 A GB 1403501A
Authority
GB
United Kingdom
Prior art keywords
prostadienoate
cis
trans
trimethylsilyloxy
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1542673A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1403501A publication Critical patent/GB1403501A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1403501 Silylated prostadienoates UPJOHN CO 30 March 1973 [27 April 1972] 15426/73 Heading C3 [Also in Division C2] Methyl 9-oxo-11αa,15α-bis-(trimethylsilyloxy)- cis-4, trans-13-prostadienoate is prepared by oxidizing methyl 9α-hydroxy-11α,15α-bis-(trimethylsilyloxy)-cia-4, trans-13-prostadienoate resulting from the silylation of methyl 9α,11α- 15α-trihydroxy-cis-4, trans-13-prostadienoate. Trimethylsilyl 9α,11α,15α tris-(trimethylsilyloxy)-cis-4, trans-13-prostadienoate is obtained by silylating 4,5-cis-didehydro-PGF 1 α.
GB1542673A 1972-04-27 1973-03-30 Prostaglandins and the preparation thereof Expired GB1403501A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24800572A 1972-04-27 1972-04-27

Publications (1)

Publication Number Publication Date
GB1403501A true GB1403501A (en) 1975-08-28

Family

ID=22937250

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1542673A Expired GB1403501A (en) 1972-04-27 1973-03-30 Prostaglandins and the preparation thereof
GB5152374A Expired GB1403502A (en) 1972-04-27 1973-03-30 Prostaglandin intermediates

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB5152374A Expired GB1403502A (en) 1972-04-27 1973-03-30 Prostaglandin intermediates

Country Status (10)

Country Link
JP (1) JPS4914447A (en)
BE (1) BE798834A (en)
CH (1) CH579043A5 (en)
DE (1) DE2320552A1 (en)
DK (1) DK551178A (en)
FR (1) FR2183039B1 (en)
GB (2) GB1403501A (en)
NL (1) NL7305565A (en)
SE (2) SE415475B (en)
ZA (1) ZA732352B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6523144B2 (en) 2015-11-17 2019-05-29 日本碍子株式会社 Gas sensor
JP5992123B1 (en) 2015-11-17 2016-09-14 日本碍子株式会社 Detection electrode of gas sensor, method of manufacturing conductive paste, gas sensor, and method of manufacturing gas sensor
JP5938133B1 (en) 2015-11-17 2016-06-22 日本碍子株式会社 Detection electrode of gas sensor, gas sensor, and method of manufacturing gas sensor
JP6186051B1 (en) 2016-07-08 2017-08-23 日本碍子株式会社 Gas sensor
JP6655515B2 (en) 2016-09-23 2020-02-26 日本碍子株式会社 Gas sensor

Also Published As

Publication number Publication date
SE7606356L (en) 1976-06-04
CH579043A5 (en) 1976-08-31
BE798834A (en) 1973-10-29
FR2183039B1 (en) 1977-11-10
ZA732352B (en) 1974-02-27
NL7305565A (en) 1973-10-30
DK551178A (en) 1978-12-06
SE415475B (en) 1980-10-06
FR2183039A1 (en) 1973-12-14
SE434153B (en) 1984-07-09
JPS4914447A (en) 1974-02-07
GB1403502A (en) 1975-08-28
DE2320552A1 (en) 1973-11-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee