GB1434090A - Halo-4-biphenylyl-butyric acid esters and amides and pharma ceutical compositions containing them - Google Patents
Halo-4-biphenylyl-butyric acid esters and amides and pharma ceutical compositions containing themInfo
- Publication number
- GB1434090A GB1434090A GB3884273A GB3884273A GB1434090A GB 1434090 A GB1434090 A GB 1434090A GB 3884273 A GB3884273 A GB 3884273A GB 3884273 A GB3884273 A GB 3884273A GB 1434090 A GB1434090 A GB 1434090A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compounds
- compound
- reacting
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 43
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- -1 alkali metal salt Chemical class 0.000 abstract 8
- 125000003545 alkoxy group Chemical group 0.000 abstract 8
- 239000002253 acid Substances 0.000 abstract 7
- 238000006243 chemical reaction Methods 0.000 abstract 6
- 229910052736 halogen Inorganic materials 0.000 abstract 6
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 150000002825 nitriles Chemical class 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 150000002576 ketones Chemical class 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- MLIREBYILWEBDM-UHFFFAOYSA-N cyanoacetic acid Chemical compound OC(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-N 0.000 abstract 2
- 238000006114 decarboxylation reaction Methods 0.000 abstract 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052744 lithium Inorganic materials 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- 229910052698 phosphorus Inorganic materials 0.000 abstract 2
- 239000011574 phosphorus Substances 0.000 abstract 2
- JALUUBQFLPUJMY-UHFFFAOYSA-N 2-(4-phenylphenyl)propanoic acid Chemical compound C1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC=C1 JALUUBQFLPUJMY-UHFFFAOYSA-N 0.000 abstract 1
- UYCUMNRCCJNSBR-UHFFFAOYSA-N 2-ethoxy-2-oxoacetic acid;hydrochloride Chemical compound Cl.CCOC(=O)C(O)=O UYCUMNRCCJNSBR-UHFFFAOYSA-N 0.000 abstract 1
- UCTNTYHJFWMUBD-UHFFFAOYSA-N 4-chloro-3-oxobutanoic acid Chemical class OC(=O)CC(=O)CCl UCTNTYHJFWMUBD-UHFFFAOYSA-N 0.000 abstract 1
- 229910010082 LiAlH Inorganic materials 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001266 acyl halides Chemical class 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000004305 biphenyl Substances 0.000 abstract 1
- 235000010290 biphenyl Nutrition 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 239000003518 caustics Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- XXTZHYXQVWRADW-UHFFFAOYSA-N diazomethanone Chemical compound [N]N=C=O XXTZHYXQVWRADW-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 150000002366 halogen compounds Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 230000020477 pH reduction Effects 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 238000003797 solvolysis reaction Methods 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 238000010792 warming Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
- C07C17/208—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being MX
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
- C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR668474A BR7406684D0 (pt) | 1973-08-16 | 1974-08-14 | Po contendo cerca de 0,2 a cerca de 5,4% em peso de carbono artigo de substrato metalico superficie trocoide e artigo de composicoa de cromio |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2240441A DE2240441A1 (de) | 1972-08-17 | 1972-08-17 | Neue biphenylderivate und verfahren zur herstellung |
DE19722261912 DE2261912A1 (de) | 1972-12-18 | 1972-12-18 | Neues verfahren zur herstellung von 3-(4-biphenylyl)-buttersaeuren |
DE19732300402 DE2300402A1 (de) | 1973-01-05 | 1973-01-05 | Neues verfahren zur herstellung von 3-(4-biphenylyl)-buttersaeuren |
DE19732309914 DE2309914A1 (de) | 1973-02-28 | 1973-02-28 | Neues verfahren zur herstellung von 3-(4-biphenylyl)-buttersaeuren |
DE19732322195 DE2322195A1 (de) | 1973-05-03 | 1973-05-03 | Neues verfahren zur herstellung von 3-(4-biphenylyl)-buttersaeuren |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1434090A true GB1434090A (en) | 1976-04-28 |
Family
ID=27510265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3884273A Expired GB1434090A (en) | 1972-08-17 | 1973-08-16 | Halo-4-biphenylyl-butyric acid esters and amides and pharma ceutical compositions containing them |
Country Status (10)
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007009389A2 (fr) * | 2005-07-22 | 2007-01-25 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Derives de propanamide substitues, preparation et utilisation de ces derives |
CN105061183A (zh) * | 2015-08-18 | 2015-11-18 | 太仓运通生物化工有限公司 | 一种1-环己烯基乙酸的制备方法 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5957870U (ja) * | 1982-10-08 | 1984-04-16 | 株式会社フジクラ | 配線板用接続具 |
JP2579766B2 (ja) * | 1986-05-07 | 1997-02-12 | 住友化学工業株式会社 | 光学活性なビフェニル誘導体およびその製造法 |
US11844278B2 (en) * | 2019-01-23 | 2023-12-12 | Lg Innotek Co., Ltd. | Thermoelectric element |
JP7345777B2 (ja) * | 2019-06-11 | 2023-09-19 | 国立大学法人千葉大学 | ケトン化合物の製造方法、カルボン酸誘導体の製造方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3385887A (en) * | 1961-02-02 | 1968-05-28 | Boots Pure Drug Co Ltd | 4-isobutylphenylacetic acid |
GB1091403A (en) * | 1964-01-24 | 1967-11-15 | Boots Pure Drug Co Ltd | Therapeutically active phenylalkane derivatives |
FR1545270A (fr) * | 1966-11-25 | 1968-11-08 | Boots Pure Drug Co Ltd | Procédé de préparation d'acides phénylalcanoïques |
NL7203400A (US06330241-20011211-M00004.png) * | 1971-03-17 | 1972-09-19 | ||
GB1382996A (en) * | 1971-03-26 | 1975-02-05 | Boots Co Ltd | Substituted biphenyls |
BE787782A (fr) * | 1971-08-20 | 1973-02-19 | Thomae Gmbh Dr K | Nouveaux 4-(4-biphenylyl)-butyramides |
GB1400448A (en) * | 1971-08-25 | 1975-07-16 | Boots Co Ltd | Oxazoline derivatives arylalkanoic acids their preparation and therapeutic compositions containing them |
-
1972
- 1972-09-13 AT AT785173A patent/ATA785173A/de not_active Application Discontinuation
-
1973
- 1973-08-15 DD DD177432*A patent/DD111204A5/xx unknown
- 1973-08-15 DD DD172904A patent/DD107900A5/xx unknown
- 1973-08-15 BG BG027679A patent/BG21846A3/xx unknown
- 1973-08-15 HU HUTO924A patent/HU168129B/hu unknown
- 1973-08-15 BG BG027680A patent/BG21847A3/xx unknown
- 1973-08-15 BG BG024326A patent/BG21010A3/xx unknown
- 1973-08-16 JP JP9205173A patent/JPS5525173B2/ja not_active Expired
- 1973-08-16 IL IL43002A patent/IL43002A0/xx unknown
- 1973-08-16 GB GB3884273A patent/GB1434090A/en not_active Expired
- 1973-08-16 AU AU59307/73A patent/AU476339B2/en not_active Expired
- 1973-08-17 NL NL7311355A patent/NL7311355A/xx unknown
- 1973-08-17 FR FR7330079A patent/FR2196171B1/fr not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007009389A2 (fr) * | 2005-07-22 | 2007-01-25 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Derives de propanamide substitues, preparation et utilisation de ces derives |
WO2007009389A3 (fr) * | 2005-07-22 | 2007-04-19 | Shanghai Inst Materia Medica | Derives de propanamide substitues, preparation et utilisation de ces derives |
CN105061183A (zh) * | 2015-08-18 | 2015-11-18 | 太仓运通生物化工有限公司 | 一种1-环己烯基乙酸的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
IL43002A0 (en) | 1973-11-28 |
BG21010A3 (bg) | 1976-01-20 |
ATA785173A (de) | 1975-01-15 |
FR2196171B1 (US06330241-20011211-M00004.png) | 1978-06-30 |
DD107900A5 (US06330241-20011211-M00004.png) | 1974-08-20 |
BG21846A3 (bg) | 1976-09-20 |
JPS5525173B2 (US06330241-20011211-M00004.png) | 1980-07-04 |
AU5930773A (en) | 1975-02-20 |
FR2196171A1 (US06330241-20011211-M00004.png) | 1974-03-15 |
JPS4980046A (US06330241-20011211-M00004.png) | 1974-08-02 |
DD111204A5 (US06330241-20011211-M00004.png) | 1975-02-05 |
NL7311355A (US06330241-20011211-M00004.png) | 1974-02-19 |
BG21847A3 (bg) | 1976-09-20 |
HU168129B (US06330241-20011211-M00004.png) | 1976-02-28 |
AU476339B2 (en) | 1976-09-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Arnold et al. | Thermal decarboxylation of unsaturated acids | |
ES426574A1 (es) | Un procedimiento para la preparacion de acidos aril-alca- noicos. | |
GB1091403A (en) | Therapeutically active phenylalkane derivatives | |
GB1226344A (US06330241-20011211-M00004.png) | ||
GB1434090A (en) | Halo-4-biphenylyl-butyric acid esters and amides and pharma ceutical compositions containing them | |
Field | Grignard Reagents of Sulfones. I. Preparation and Reactions of β-Phenyl-β-hydroxyethyl Phenyl Sulfone1 | |
Hauser et al. | Aldol Condensation of Esters with Ketones or Aldehydes to Form β-Hydroxy Esters by Lithium Amide. Comparison with the Reformatsky Reaction1 | |
GB1491498A (en) | 2-(substituted phenyl)-propionic acids and their pharmaceutical compositions | |
EP1077208A3 (de) | Verfahren zur Herstellung von (Bis-(trifluormethyl)-phenyl)-essigsäuren und deren Alkylestern sowie (Bis-(trifluormethyl)-phenyl)-malonsäure-dialkylester | |
Nobuhara | Syntheses of Unsaturated Lactones: Part III. Flavorous Nature of Some δ-Lactones Having the Double Bond at Various Sites | |
GB1432649A (US06330241-20011211-M00004.png) | ||
GB1266757A (US06330241-20011211-M00004.png) | ||
Bachmann et al. | Reactions of Propiolic Esters. I. Addition to the Carbonyl Group of Ketones in the Presence of Sodamide | |
Hackett et al. | Methoxyphenylthiotrimethylsilylmethyllithium a convenient reagent for the homologation of carbonyl compounds | |
GB1420802A (en) | Substituted geranyl acetic acids and pharmaceutical compositions thereof | |
GB1382267A (en) | Phenylalkanoic acid derivatives | |
FR2172868A1 (en) | Carboxy substd benzophenone derivs - as analgesics and antiinflammatory agents | |
GB700391A (en) | Improvements in or relating to basic esters and processes for preparing the same | |
ES271526A1 (es) | Procedimiento para la producciën de nuevos compuestos heterociclicos | |
GB1429287A (en) | Process for the preparation of 3-alkyl-cyclopentane-1,2-diones and intermediates therefor | |
GB1249492A (en) | New aryloxyalkanoic acid and salts thereof | |
SU520907A3 (ru) | Способ получени замещенной бифенилилмасл ной кислоты или ее соли | |
US3320306A (en) | Process for the preparation of 4-(2-methylenealkanoyl)phenoxy alkanoic acids by decarboxylation | |
GB1304502A (US06330241-20011211-M00004.png) | ||
Brooke et al. | Partially fluorinated heterocyclic compounds. Part IX. The syntheses of 4, 5, 6, 7-tetrafluorobenzo [b] furan and 4, 5, 6, 7-tetrafluoro-2-phenylbenzo [b] furan by a new cyclisation reaction, and the attempted syntheses of related compounds by conventional methods |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PLNP | Patent lapsed through nonpayment of renewal fees |