GB1426910A - 3-deoxy derivatives of neamine and its related aminoglycosidic antibiotics and the production thereof - Google Patents

3-deoxy derivatives of neamine and its related aminoglycosidic antibiotics and the production thereof

Info

Publication number
GB1426910A
GB1426910A GB5568573A GB5568573A GB1426910A GB 1426910 A GB1426910 A GB 1426910A GB 5568573 A GB5568573 A GB 5568573A GB 5568573 A GB5568573 A GB 5568573A GB 1426910 A GB1426910 A GB 1426910A
Authority
GB
United Kingdom
Prior art keywords
deoxy
compounds
neamine
kanamycin
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5568573A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of GB1426910A publication Critical patent/GB1426910A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB5568573A 1972-12-08 1973-11-30 3-deoxy derivatives of neamine and its related aminoglycosidic antibiotics and the production thereof Expired GB1426910A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12243672A JPS57876B2 (de) 1972-12-08 1972-12-08

Publications (1)

Publication Number Publication Date
GB1426910A true GB1426910A (en) 1976-03-03

Family

ID=14835788

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5568573A Expired GB1426910A (en) 1972-12-08 1973-11-30 3-deoxy derivatives of neamine and its related aminoglycosidic antibiotics and the production thereof

Country Status (10)

Country Link
JP (1) JPS57876B2 (de)
AR (1) AR201932A1 (de)
AT (1) AT332543B (de)
BE (1) BE808393A (de)
CA (1) CA1016165A (de)
DE (2) DE2366288C3 (de)
ES (1) ES421251A1 (de)
FR (1) FR2209745B1 (de)
GB (1) GB1426910A (de)
NL (1) NL164040C (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0173614A2 (de) * 1984-08-02 1986-03-05 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 3'-Fluor-3'-Deoxykanamycin a und seine Herstellung
EP0185323A2 (de) * 1984-12-15 1986-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2',3'-Dideoxy-2'-fluorokanamycin-A und seine 1-N-(alpha-hydroxy-omega-aminoalkanoyl)-Derivate

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116642A (en) * 1974-08-01 1976-02-10 Meiji Seika Co 3** deokishineamin oyobi sonokanrenkoseibutsushitsuno seizoho
FR2290908A1 (fr) * 1974-11-13 1976-06-11 Roussel Uclaf Nouveau derive aminoglycosidique et ses sels, leur procede de preparation et leur application comme medicaments
FR2358156A1 (fr) * 1976-03-31 1978-02-10 Roussel Uclaf Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments
JPS5663993A (en) * 1979-10-30 1981-05-30 Microbial Chem Res Found Novel preparation of tobramycin
JPH0544930Y2 (de) * 1986-01-24 1993-11-16
JPH01157976A (ja) * 1987-12-16 1989-06-21 Towa Kasei Kogyo Kk （４ｓ，５ｓ）−４，５−シクロヘキシリデンジオキシ−２−シクロペンテン−１−オンとその鏡像体及びそれらの合成中間体並びにそれらの製造方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0173614A2 (de) * 1984-08-02 1986-03-05 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 3'-Fluor-3'-Deoxykanamycin a und seine Herstellung
EP0173614A3 (en) * 1984-08-02 1986-08-13 Microbial Chem Res Found 3'-fluoro-3'-deoxykanamycin a and the production thereof
EP0185323A2 (de) * 1984-12-15 1986-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2',3'-Dideoxy-2'-fluorokanamycin-A und seine 1-N-(alpha-hydroxy-omega-aminoalkanoyl)-Derivate
EP0185323A3 (en) * 1984-12-15 1986-08-06 Microbial Chem Res Found 2',3'-dideoxy-2'-fluorokanamycin a and 1-n-(alpha-hydroxy-omega-aminoalkanoyl) derivatives thereof

Also Published As

Publication number Publication date
JPS57876B2 (de) 1982-01-08
AR201932A1 (es) 1975-04-30
NL164040B (nl) 1980-06-16
ES421251A1 (es) 1976-04-01
DE2366288B2 (de) 1981-07-02
DE2366288C3 (de) 1982-03-18
DE2361159A1 (de) 1974-06-20
ATA1031873A (de) 1976-01-15
DE2361159C3 (de) 1982-04-29
BE808393A (fr) 1974-03-29
NL164040C (nl) 1980-11-17
AT332543B (de) 1976-10-11
FR2209745A1 (de) 1974-07-05
JPS4980038A (de) 1974-08-02
CA1016165A (en) 1977-08-23
NL7316777A (de) 1974-06-11
FR2209745B1 (de) 1977-09-23
DE2361159B2 (de) 1981-07-02

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19931129