GB1425049A - Substituted 2-hydroxy-2-phenylethyl-amines - Google Patents
Substituted 2-hydroxy-2-phenylethyl-aminesInfo
- Publication number
- GB1425049A GB1425049A GB2508273A GB2508273A GB1425049A GB 1425049 A GB1425049 A GB 1425049A GB 2508273 A GB2508273 A GB 2508273A GB 2508273 A GB2508273 A GB 2508273A GB 1425049 A GB1425049 A GB 1425049A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetoxy
- dimethoxy
- hydroxy
- acetophenone
- nhch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical class NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 title abstract 2
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Natural products CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- -1 4- methyl - 1 - piperazinyl Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- MYKNWGRGAHWCRM-UHFFFAOYSA-N (4-carbamoyl-2,6-dimethoxyphenyl) acetate Chemical compound COC=1C=C(C(=O)N)C=C(C1OC(C)=O)OC MYKNWGRGAHWCRM-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2891972A IT1044224B (it) | 1972-09-07 | 1972-09-07 | 2 idrossi 2 feniletilamine sostituite quali sostanze vasoattive e processo per la loro preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1425049A true GB1425049A (en) | 1976-02-18 |
Family
ID=11224633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2508273A Expired GB1425049A (en) | 1972-09-07 | 1973-05-25 | Substituted 2-hydroxy-2-phenylethyl-amines |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS4985035A (enrdf_load_stackoverflow) |
| DE (1) | DE2344681A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2198743B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1425049A (enrdf_load_stackoverflow) |
| IT (1) | IT1044224B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006134352A1 (en) * | 2005-06-15 | 2006-12-21 | Biosynth As | Method for the synthesis of anthocyanins |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56128740A (en) * | 1980-03-14 | 1981-10-08 | Grelan Pharmaceut Co Ltd | Preparation of erythro-2-amino-1-phenylpropanol derivative |
| AUPN977296A0 (en) * | 1996-05-10 | 1996-06-06 | Monash University | Pharmaceutical agents |
| BE1014245A4 (fr) * | 2001-04-03 | 2003-07-01 | Malak Jean | Composes chimiques derives de l'octopamine et leurs utilisations en tant qu'agonistes beta 3-adrenergiques. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1143626B (it) * | 1968-04-18 | 1986-10-22 | Zambeletti L Dr Spa | Processo per la fabbricazione di (13,5 dimetossi 4 idrossi) 2 monometilamminoetanolo,farmaco ad azione ipertensiva |
-
1972
- 1972-09-07 IT IT2891972A patent/IT1044224B/it active
-
1973
- 1973-05-25 GB GB2508273A patent/GB1425049A/en not_active Expired
- 1973-08-30 JP JP48097804A patent/JPS4985035A/ja active Pending
- 1973-09-05 DE DE19732344681 patent/DE2344681A1/de active Pending
- 1973-09-06 FR FR7332135A patent/FR2198743B1/fr not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006134352A1 (en) * | 2005-06-15 | 2006-12-21 | Biosynth As | Method for the synthesis of anthocyanins |
| AU2006258853B2 (en) * | 2005-06-15 | 2012-02-23 | Biosynth As | Method for the synthesis of anthocyanins |
| CN101198616B (zh) * | 2005-06-15 | 2012-05-23 | 生物合成股份有限公司 | 合成花色素苷的方法 |
| US8513395B2 (en) | 2005-06-15 | 2013-08-20 | Biosynth As | Method for the synthesis of anthocyanins |
| NO338953B1 (no) * | 2005-06-15 | 2016-11-07 | Biosynth As | Fremgangsmåte til syntese av antocyaniner |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2198743A1 (enrdf_load_stackoverflow) | 1974-04-05 |
| IT1044224B (it) | 1980-03-20 |
| FR2198743B1 (enrdf_load_stackoverflow) | 1977-01-28 |
| JPS4985035A (enrdf_load_stackoverflow) | 1974-08-15 |
| DE2344681A1 (de) | 1974-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |