GB1424302A - 5alpha-hydroxy-gona-9,11-dienes and processes for their preparation - Google Patents

5alpha-hydroxy-gona-9,11-dienes and processes for their preparation

Info

Publication number
GB1424302A
GB1424302A GB400574A GB400574A GB1424302A GB 1424302 A GB1424302 A GB 1424302A GB 400574 A GB400574 A GB 400574A GB 400574 A GB400574 A GB 400574A GB 1424302 A GB1424302 A GB 1424302A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
formula
action
ketal
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB400574A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB1424302A publication Critical patent/GB1424302A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB400574A 1973-01-29 1974-01-29 5alpha-hydroxy-gona-9,11-dienes and processes for their preparation Expired GB1424302A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7302991A FR2215416B1 (enExample) 1973-01-29 1973-01-29

Publications (1)

Publication Number Publication Date
GB1424302A true GB1424302A (en) 1976-02-11

Family

ID=9113975

Family Applications (1)

Application Number Title Priority Date Filing Date
GB400574A Expired GB1424302A (en) 1973-01-29 1974-01-29 5alpha-hydroxy-gona-9,11-dienes and processes for their preparation

Country Status (12)

Country Link
US (1) US3872092A (enExample)
JP (1) JPS5826359B2 (enExample)
BE (1) BE810249A (enExample)
CA (1) CA1037025A (enExample)
CH (1) CH591515A5 (enExample)
DE (1) DE2404130A1 (enExample)
DK (1) DK137928B (enExample)
FR (1) FR2215416B1 (enExample)
GB (1) GB1424302A (enExample)
IE (1) IE38805B1 (enExample)
LU (1) LU69253A1 (enExample)
NL (1) NL7401106A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51468A (en) * 1976-02-23 1981-01-30 Sparamedica Ag 17 -hydroxy- -d-homosteroid derivatives,their preparation and pharmaceutical compositions containing them
DE4232521A1 (de) * 1992-09-22 1994-03-24 Schering Ag Gestagen wirksame 4,5;11,12-Estradiene, Verfahren zu ihrer Herstellung, diese Estradiene enthaltende Arzneimittel sowie deren Verwendung zur Herstellung von Arzneimitteln
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates

Also Published As

Publication number Publication date
IE38805B1 (en) 1978-06-07
FR2215416A1 (enExample) 1974-08-23
CA1037025A (fr) 1978-08-22
LU69253A1 (enExample) 1974-09-25
DE2404130A1 (de) 1974-08-01
FR2215416B1 (enExample) 1976-09-10
DK137928C (enExample) 1978-10-30
IE38805L (en) 1974-07-29
US3872092A (en) 1975-03-18
CH591515A5 (enExample) 1977-09-30
NL7401106A (enExample) 1974-07-31
BE810249A (fr) 1974-07-29
JPS5826359B2 (ja) 1983-06-02
JPS5046655A (enExample) 1975-04-25
DK137928B (da) 1978-06-05

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee