GB1422679A - Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same - Google Patents

Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same

Info

Publication number
GB1422679A
GB1422679A GB4960873A GB4960873A GB1422679A GB 1422679 A GB1422679 A GB 1422679A GB 4960873 A GB4960873 A GB 4960873A GB 4960873 A GB4960873 A GB 4960873A GB 1422679 A GB1422679 A GB 1422679A
Authority
GB
United Kingdom
Prior art keywords
hydrogen atom
phenoxy
methylpropionic acid
reacting
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4960873A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Funai Pharmaceutical Industries Ltd
Original Assignee
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11506872A external-priority patent/JPS525492B2/ja
Priority claimed from JP293373A external-priority patent/JPS525493B2/ja
Priority claimed from JP293473A external-priority patent/JPS525494B2/ja
Application filed by Funai Pharmaceutical Industries Ltd filed Critical Funai Pharmaceutical Industries Ltd
Publication of GB1422679A publication Critical patent/GB1422679A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB4960873A 1972-11-16 1973-10-24 Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same Expired GB1422679A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11506872A JPS525492B2 (enExample) 1972-11-16 1972-11-16
JP293373A JPS525493B2 (enExample) 1972-12-26 1972-12-26
JP293473A JPS525494B2 (enExample) 1972-12-26 1972-12-26

Publications (1)

Publication Number Publication Date
GB1422679A true GB1422679A (en) 1976-01-28

Family

ID=27275597

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4960873A Expired GB1422679A (en) 1972-11-16 1973-10-24 Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same

Country Status (5)

Country Link
CH (1) CH589589A5 (enExample)
DE (1) DE2356655C3 (enExample)
FR (1) FR2207120B1 (enExample)
GB (1) GB1422679A (enExample)
NL (1) NL7315171A (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030251A1 (de) * 1979-12-11 1981-06-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von (Phenoxi, bzw. Benzyl)- phenoxipropionsäuren und ihren Alkalisalzen
EP0030585A1 (de) * 1979-12-11 1981-06-24 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Phenoxipropionsäuren und ihren Alkalisalzen
WO2003059875A3 (en) * 2002-01-15 2003-12-04 Sigma Tau Ind Farmaceuti DERIVATIVES OF α-PHENYLTHIOCARBOXYLIC AND α-PHENYLOXY-CARBOXYLIC ACIDS USEFUL FOR THE TREATMENT OF DISEASES RESPONDING TO PPARα ACTIVATION
WO2004056355A1 (en) * 2002-12-19 2004-07-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. USE OF α-PHENYLTHIOCARBOXYLIC AND α-PHENYLOXYCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
US4182902A (en) 1973-12-27 1980-01-08 Siegfried Aktiengesellschaft Novel cholesterol-lowering compounds
CH617417A5 (enExample) * 1973-12-27 1980-05-30 Siegfried Ag
NL7416412A (nl) * 1973-12-27 1975-07-01 Siegfried Ag Werkwijze ter bereiding van nieuwe cholesterol- gende verbindingen.
US4235896A (en) * 1975-02-12 1980-11-25 Orchimed S.A. Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same
US4179515A (en) * 1975-02-12 1979-12-18 Orchimed S. A. Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition
JPS5195049A (en) * 1975-02-12 1976-08-20 * **********so*****no***tsu*****************************************ni*no
AT346313B (de) * 1976-10-18 1978-11-10 Hauser Chepharin Paul Verfahren zur herstellung des magnesiumsalzes der p-chlorphenoxyisobuttersaeure
JPS5649906B2 (en) * 1978-05-12 1981-11-25 Boehringer Mannheim Gmbh Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxy**isoethylacetic acid
US4214095A (en) * 1979-01-25 1980-07-22 Siegfried Aktiengesellschaft Chlorobenzyl phenoxy alkoxylates
US4665226A (en) * 1985-12-09 1987-05-12 Warner-Lambert Company Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
WO1989006643A1 (fr) * 1988-01-22 1989-07-27 Kharkovsky Nauchno-Issledovatelsky Institut Endokr ACIDE n-CHLOROPHENOXYISOBUTIRIQUE D'ETHER UNDECYLIQUE ET PREPARATION PHARMACEUTIQUE LE CONTENANT POUR TRAITER L'HYPERLIPEMIE

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
DE1668896C3 (de) * 1968-01-11 1974-08-29 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Phenoxyalkancarbonsäuren ihre Salze und Ester und Verfahren zur Herstellung dieser Verbindungen

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030251A1 (de) * 1979-12-11 1981-06-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von (Phenoxi, bzw. Benzyl)- phenoxipropionsäuren und ihren Alkalisalzen
EP0030585A1 (de) * 1979-12-11 1981-06-24 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Phenoxipropionsäuren und ihren Alkalisalzen
WO2003059875A3 (en) * 2002-01-15 2003-12-04 Sigma Tau Ind Farmaceuti DERIVATIVES OF α-PHENYLTHIOCARBOXYLIC AND α-PHENYLOXY-CARBOXYLIC ACIDS USEFUL FOR THE TREATMENT OF DISEASES RESPONDING TO PPARα ACTIVATION
AU2003209679B2 (en) * 2002-01-15 2009-02-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Derivatives of alpha-phenylthiocarboxylic and alpha-phenyloxy-carboxylic acids useful for the treatment of diseases responding to PPARalpha activation
KR100975961B1 (ko) * 2002-01-15 2010-08-16 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. ＰＰＡＲα활성화에 반응하는 질병의 치료에 유용한α－페닐티오카르복시산 및＄Ｇ（ａ）－페닐옥시－카르복시산의 유도체
WO2004056355A1 (en) * 2002-12-19 2004-07-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. USE OF α-PHENYLTHIOCARBOXYLIC AND α-PHENYLOXYCARBOXYLIC ACIDS WITH SERUM-GLUCOSE-LOWERING AND SERUM-LIPID-LOWERING ACTIVITY
US7375124B2 (en) 2002-12-19 2008-05-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of α-phenylthiocarboxylic and α-phenyloxycarboxylic acids with serum-glucose-lowering and serum-lipid-lowering activity
CN100393309C (zh) * 2002-12-19 2008-06-11 希格马托制药工业公司 具有降低血清葡萄糖和降低血清脂质活性的α-苯硫基羧酸和α-苯氧基羧酸的用途
AU2003288546B2 (en) * 2002-12-19 2009-04-30 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of alpha-phenylthiocarboxylic and alpha-phenyloxycarboxylic acids with serum-glucose-lowering and serum-lipid-lowering activity
AU2003288546B8 (en) * 2002-12-19 2009-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of alpha-phenylthiocarboxylic and alpha-phenyloxycarboxylic acids with serum-glucose-lowering and serum-lipid-lowering activity

Also Published As

Publication number Publication date
FR2207120B1 (enExample) 1978-11-17
NL7315171A (enExample) 1974-05-20
DE2356655C3 (de) 1981-12-17
DE2356655B2 (de) 1980-09-25
DE2356655A1 (de) 1974-05-22
FR2207120A1 (enExample) 1974-06-14
CH589589A5 (enExample) 1977-07-15

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19931023