GB1418338A - Sulphone salts deriving from 2,5-dihydroxy benzene monosulphonic and 2,5-dihydroxy genzene disulphonic acids - Google Patents

Sulphone salts deriving from 2,5-dihydroxy benzene monosulphonic and 2,5-dihydroxy genzene disulphonic acids

Info

Publication number
GB1418338A
GB1418338A GB2114273A GB2114273A GB1418338A GB 1418338 A GB1418338 A GB 1418338A GB 2114273 A GB2114273 A GB 2114273A GB 2114273 A GB2114273 A GB 2114273A GB 1418338 A GB1418338 A GB 1418338A
Authority
GB
United Kingdom
Prior art keywords
dihydroxy
sulphone
genzene
iii
disulphonic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2114273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of GB1418338A publication Critical patent/GB1418338A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

1418338 Aromatic - sulphone - sulphonic acid salts LABORATORIOS DEL DR ESTEVE SA 3 May 1973 [17 May 1972] 21142/73 Heading C2C Novel compounds (I), (II) and (III) where R is aryl, alkylaryl or aralkyl and B is an alkali metal cation, an equivalent of an alkaline earth metal cation, ammonium or an optionally substituted amine cation, are made by reacting compounds IV (themselves obtained by oxidizing corresponding hydroquinones with HNO 3 ) with R.SO 2 H, where, when R 1 is H, R 2 is H or -SO 3 B and when R 1 is -SO 3 B, R 2 is H. Pharmaceutical preparations showing hemostatic, hypocholesterolemic, hypoglycedemic and hypolipemic actions contain (I), (II) and/or (III) as active ingredient. Administration is orally or parenterally.
GB2114273A 1972-05-17 1973-05-03 Sulphone salts deriving from 2,5-dihydroxy benzene monosulphonic and 2,5-dihydroxy genzene disulphonic acids Expired GB1418338A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH732572A CH551956A (en) 1972-05-17 1972-05-17 PROCESS FOR THE PREPARATION OF SULPHONES SALTS DERIVED FROM 2,5-DIHYDROXYBENZENEMONOSULPHONIC AND 2,5DIHYDROXYBENZENEDISULPHONIC ACIDS.

Publications (1)

Publication Number Publication Date
GB1418338A true GB1418338A (en) 1975-12-17

Family

ID=4323359

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2114273A Expired GB1418338A (en) 1972-05-17 1973-05-03 Sulphone salts deriving from 2,5-dihydroxy benzene monosulphonic and 2,5-dihydroxy genzene disulphonic acids

Country Status (17)

Country Link
JP (1) JPS5629663B2 (en)
AR (1) AR205083A1 (en)
BE (1) BE799486A (en)
CA (1) CA1007654A (en)
CH (1) CH551956A (en)
CS (1) CS191217B2 (en)
DD (1) DD108286A5 (en)
DE (1) DE2323722A1 (en)
ES (1) ES414364A1 (en)
FR (1) FR2184930B1 (en)
GB (1) GB1418338A (en)
HU (1) HU167264B (en)
NL (1) NL7305917A (en)
PL (2) PL89246B1 (en)
RO (1) RO66088A (en)
SE (1) SE388195B (en)
ZA (1) ZA733135B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114539101A (en) * 2020-11-26 2022-05-27 南京长澳医药科技有限公司 Method for preparing calcium dobesilate genotoxic impurities

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH591437A5 (en) * 1974-05-08 1977-09-15 Esteve Dr Lab Del Sa
ZA745083B (en) * 1973-09-11 1975-08-27 Esteve Labor Dr Process for the preparation of monoesters and diesters of 2,5-dihydroxy-benzene-sulphonic acid
CH591438A5 (en) * 1975-05-16 1977-09-15 Esteve Dr Lab Del Sa
JP4605726B2 (en) * 1997-09-02 2011-01-05 日本曹達株式会社 Molecular compounds containing phenol derivatives as component compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114539101A (en) * 2020-11-26 2022-05-27 南京长澳医药科技有限公司 Method for preparing calcium dobesilate genotoxic impurities

Also Published As

Publication number Publication date
DD108286A5 (en) 1974-09-12
HU167264B (en) 1975-09-27
CS191217B2 (en) 1979-06-29
CH551956A (en) 1974-07-31
FR2184930B1 (en) 1977-01-21
SE388195B (en) 1976-09-27
JPS5629663B2 (en) 1981-07-09
AR205083A1 (en) 1976-04-05
ES414364A1 (en) 1976-02-01
JPS4941338A (en) 1974-04-18
NL7305917A (en) 1973-11-20
FR2184930A1 (en) 1973-12-28
AU5533773A (en) 1974-11-07
BE799486A (en) 1973-11-14
ZA733135B (en) 1974-04-24
PL92437B1 (en) 1977-04-30
DE2323722A1 (en) 1973-11-29
PL89246B1 (en) 1976-11-30
CA1007654A (en) 1977-03-29
RO66088A (en) 1981-06-22

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee