GB1416397A - Process for the preparation of 1-hydroxy-2-pyridones - Google Patents
Process for the preparation of 1-hydroxy-2-pyridonesInfo
- Publication number
- GB1416397A GB1416397A GB1358773A GB1358773A GB1416397A GB 1416397 A GB1416397 A GB 1416397A GB 1358773 A GB1358773 A GB 1358773A GB 1358773 A GB1358773 A GB 1358773A GB 1416397 A GB1416397 A GB 1416397A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- alkyl
- carbon atoms
- hydrogen atom
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SNUSZUYTMHKCPM-UHFFFAOYSA-N 1-hydroxypyridin-2-one Chemical class ON1C=CC=CC1=O SNUSZUYTMHKCPM-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 alkyl radical Chemical class 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- ZPSJGADGUYYRKE-UHFFFAOYSA-N 2H-pyran-2-one Chemical compound O=C1C=CC=CO1 ZPSJGADGUYYRKE-UHFFFAOYSA-N 0.000 abstract 1
- 125000001054 5 membered carbocyclic group Chemical group 0.000 abstract 1
- 125000004008 6 membered carbocyclic group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000003927 aminopyridines Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical group C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- HRDXJKGNWSUIBT-UHFFFAOYSA-N methoxybenzene Chemical group [CH2]OC1=CC=CC=C1 HRDXJKGNWSUIBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722214608 DE2214608C3 (de) | 1972-03-25 | Verfahren zur Herstellung von J-Hydroxy-2-pyridonen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1416397A true GB1416397A (en) | 1975-12-03 |
Family
ID=5840130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1358773A Expired GB1416397A (en) | 1972-03-25 | 1973-03-21 | Process for the preparation of 1-hydroxy-2-pyridones |
Country Status (27)
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2146990A (en) * | 1983-09-23 | 1985-05-01 | Nat Res Dev | 1-hydroxypyrid-2-ones |
| US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
| USRE34313E (en) * | 1983-09-23 | 1993-07-13 | National Research Development Corporation | Pharmaceutical compositions |
| WO2004078727A1 (ja) * | 2003-02-05 | 2004-09-16 | Nippon Soda Co., Ltd. | 新規６－フルオロアルキル－２（１ｈ）－ピリジノン、６－フルオロアルキルピリジン化合物及びその製造方法 |
| WO2019228988A1 (en) * | 2018-05-30 | 2019-12-05 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| EP4122918A1 (en) * | 2021-07-19 | 2023-01-25 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024115319A1 (en) * | 2022-11-28 | 2024-06-06 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024104987A3 (en) * | 2022-11-16 | 2024-06-27 | Clariant International Ltd | Process for the preparation of piroctone, including crystallization or precipitation, piroctone particles and process for the preparation of piroctone olamine |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4178242A (en) * | 1975-11-11 | 1979-12-11 | Anic S.P.A. | Method for the purification of sewage waters which contain organic compounds of an anionic character |
| JPS5323145A (en) * | 1976-07-20 | 1978-03-03 | Kurita Water Ind Ltd | Method of dehydrating sludge |
| JPS54144759A (en) * | 1978-04-29 | 1979-11-12 | Tobata Tekko Kk | Method of decoloring waste water containing dyestuffs |
| US5817825A (en) * | 1994-11-02 | 1998-10-06 | Hoechst Aktiengesellschaft | Process for the preparation of 1-hydroxy-2-pyridones |
-
1973
- 1973-03-11 EG EG86/73A patent/EG10850A/xx active
- 1973-03-12 CA CA166,905A patent/CA979449A/en not_active Expired
- 1973-03-20 ES ES412847A patent/ES412847A1/es not_active Expired
- 1973-03-20 NL NLAANVRAGE7303870,A patent/NL175177C/xx not_active IP Right Cessation
- 1973-03-21 GB GB1358773A patent/GB1416397A/en not_active Expired
- 1973-03-21 BG BG023052A patent/BG22817A3/xx unknown
- 1973-03-21 BG BG025589A patent/BG22814A3/xx unknown
- 1973-03-22 YU YU784/73A patent/YU35583B/xx unknown
- 1973-03-22 PH PH14455*UA patent/PH9480A/en unknown
- 1973-03-22 CH CH420473A patent/CH579050A5/xx not_active IP Right Cessation
- 1973-03-22 KR KR7300464A patent/KR780000095B1/ko not_active Expired
- 1973-03-22 FI FI896/73A patent/FI55331C/fi active
- 1973-03-23 JP JP48032786A patent/JPS5233B2/ja not_active Expired
- 1973-03-23 SE SE7304111A patent/SE383151B/xx unknown
- 1973-03-23 ZA ZA732042A patent/ZA732042B/xx unknown
- 1973-03-23 DK DK162073A patent/DK139966C/da not_active IP Right Cessation
- 1973-03-23 RO RO7300074280A patent/RO62622A/ro unknown
- 1973-03-23 HU HUHO1556A patent/HU166579B/hu unknown
- 1973-03-23 DD DD169759A patent/DD105612A5/xx unknown
- 1973-03-23 NO NO1205/73A patent/NO139861C/no unknown
- 1973-03-23 SU SU1896821A patent/SU468418A3/ru active
- 1973-03-23 AT AT262473A patent/AT327190B/de not_active IP Right Cessation
- 1973-03-23 AR AR247210A patent/AR219038A1/es active
- 1973-03-24 PL PL1973161446A patent/PL91738B1/pl unknown
- 1973-03-26 CS CS7300002187A patent/CS183686B2/cs unknown
- 1973-03-26 BE BE129278A patent/BE797346A/xx not_active IP Right Cessation
- 1973-03-26 FR FR7310713A patent/FR2177963B1/fr not_active Expired
-
1978
- 1978-12-30 MY MY114/78A patent/MY7800114A/xx unknown
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2146990A (en) * | 1983-09-23 | 1985-05-01 | Nat Res Dev | 1-hydroxypyrid-2-ones |
| US4587240A (en) * | 1983-09-23 | 1986-05-06 | National Research Development Corp. | Pharmaceutical compositions |
| US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
| US5104865A (en) * | 1983-09-23 | 1992-04-14 | National Research Development Corporation | Iron complexes of hydroxypyridones useful for treating iron overload |
| USRE34313E (en) * | 1983-09-23 | 1993-07-13 | National Research Development Corporation | Pharmaceutical compositions |
| WO2004078727A1 (ja) * | 2003-02-05 | 2004-09-16 | Nippon Soda Co., Ltd. | 新規６－フルオロアルキル－２（１ｈ）－ピリジノン、６－フルオロアルキルピリジン化合物及びその製造方法 |
| WO2019228988A1 (en) * | 2018-05-30 | 2019-12-05 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| CN112351970A (zh) * | 2018-05-30 | 2021-02-09 | 科莱恩国际有限公司 | 2-羟基吡啶-1-氧化物或其衍生物的形成方法 |
| US20210214307A1 (en) * | 2018-05-30 | 2021-07-15 | Clariant International Ltd. | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| US11753379B2 (en) * | 2018-05-30 | 2023-09-12 | Clariant International Ltd | Process for forming 2-hydroxypyridine-1-oxide or derivatives thereof |
| EP4122918A1 (en) * | 2021-07-19 | 2023-01-25 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2023001781A1 (en) * | 2021-07-19 | 2023-01-26 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
| WO2024104987A3 (en) * | 2022-11-16 | 2024-06-27 | Clariant International Ltd | Process for the preparation of piroctone, including crystallization or precipitation, piroctone particles and process for the preparation of piroctone olamine |
| WO2024115319A1 (en) * | 2022-11-28 | 2024-06-06 | Clariant International Ltd | Process for the preparation of n-hydroxypyridone compounds |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930320 |