GB1403584A - Control medicaments - Google Patents

Control medicaments

Info

Publication number
GB1403584A
GB1403584A GB2357672A GB2357672A GB1403584A GB 1403584 A GB1403584 A GB 1403584A GB 2357672 A GB2357672 A GB 2357672A GB 2357672 A GB2357672 A GB 2357672A GB 1403584 A GB1403584 A GB 1403584A
Authority
GB
United Kingdom
Prior art keywords
microcapsules
ampicillin
pvp
esters
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2357672A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB2357672A priority Critical patent/GB1403584A/en
Priority to IE775/73A priority patent/IE37637B1/xx
Priority to DK277173AA priority patent/DK134424B/da
Priority to CA171,807A priority patent/CA1025359A/en
Priority to BE131326A priority patent/BE799783A/xx
Priority to NL7307033A priority patent/NL7307033A/xx
Priority to ES414908A priority patent/ES414908A1/es
Priority to IL42312A priority patent/IL42312A/en
Priority to HUBE1170A priority patent/HU167559B/hu
Priority to AT439473A priority patent/AT337902B/de
Priority to FR7318155A priority patent/FR2185390B1/fr
Priority to DE2325410A priority patent/DE2325410A1/de
Priority to JP48056245A priority patent/JPS4954518A/ja
Priority to ZA00733406A priority patent/ZA733406B/xx
Priority to AR248141A priority patent/AR197900A1/es
Priority to AU55965/73A priority patent/AU475493B2/en
Priority to JP48092341A priority patent/JPS49116220A/ja
Priority to DK190774A priority patent/DK134423C/da
Priority to DK692174A priority patent/DK136844B/da
Publication of GB1403584A publication Critical patent/GB1403584A/en
Priority to US05/673,441 priority patent/US4016254A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB2357672A 1972-05-19 1972-05-19 Control medicaments Expired GB1403584A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments
IE775/73A IE37637B1 (en) 1972-05-19 1973-05-15 Improvements in or relating to control medicaments
DK277173AA DK134424B (da) 1972-05-19 1973-05-17 Fremgangsmåde til fremstilling af et pulver, i det væsentlige indeholdende mikrokapsler af ampicillin-trihydrat eller amoxycillin-trihydrat overtrukket med polyvinylpyrrolidon, ved spraytørring.
AT439473A AT337902B (de) 1972-05-19 1973-05-18 Verfahren zur herstellung eines pharmazeutischen pulvers
BE131326A BE799783A (fr) 1972-05-19 1973-05-18 Compositions pharmaceutiques comprenant des microcapsules de medicament de 100 a 300 microns en moyenne
NL7307033A NL7307033A (de) 1972-05-19 1973-05-18
ES414908A ES414908A1 (es) 1972-05-19 1973-05-18 Un procedimiento para la preparacion de un polvo que com- prende microcapsulas.
IL42312A IL42312A (en) 1972-05-19 1973-05-18 Pharmaceutical preparations containing ampicillin trihydrate or amoxicillin trihydrate in tiny capsules and their manufacture
HUBE1170A HU167559B (de) 1972-05-19 1973-05-18
CA171,807A CA1025359A (en) 1972-05-19 1973-05-18 Microencapsulated medical powders
FR7318155A FR2185390B1 (de) 1972-05-19 1973-05-18
DE2325410A DE2325410A1 (de) 1972-05-19 1973-05-18 Wirkstoffhaltiges pulver, verfahren zu seiner herstellung und verwendung dieses pulvers zur herstellung pharmazeutischer praeparate in verabreichungsform
JP48056245A JPS4954518A (de) 1972-05-19 1973-05-19
ZA00733406A ZA733406B (en) 1972-05-19 1973-05-21 Pharmaceutical formulations
AR248141A AR197900A1 (es) 1972-05-19 1973-05-21 Procedimiento para la preparacion de formas pulverulentas sin polvillo
AU55965/73A AU475493B2 (en) 1972-05-19 1973-05-21 Pharmaceutical formulations
JP48092341A JPS49116220A (de) 1972-05-19 1973-08-16
DK190774A DK134423C (da) 1972-05-19 1974-04-05 Apparat til optagelse af et ultralyd-snitbillede
DK692174A DK136844B (da) 1972-05-19 1974-12-30 Fremgangsmåde til fremstilling af et farmaceutisk præparat indeholdende amoxycillin-trihydrat eller ampicillin-trihydrat i en dosisform, som kan anvendes til human eller veterinær administration.
US05/673,441 US4016254A (en) 1972-05-19 1976-04-05 Pharmaceutical formulations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Publications (1)

Publication Number Publication Date
GB1403584A true GB1403584A (en) 1975-08-28

Family

ID=10197917

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2357672A Expired GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Country Status (16)

Country Link
JP (2) JPS4954518A (de)
AR (1) AR197900A1 (de)
AT (1) AT337902B (de)
AU (1) AU475493B2 (de)
BE (1) BE799783A (de)
CA (1) CA1025359A (de)
DE (1) DE2325410A1 (de)
DK (2) DK134424B (de)
ES (1) ES414908A1 (de)
FR (1) FR2185390B1 (de)
GB (1) GB1403584A (de)
HU (1) HU167559B (de)
IE (1) IE37637B1 (de)
IL (1) IL42312A (de)
NL (1) NL7307033A (de)
ZA (1) ZA733406B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4011956A1 (de) * 1989-04-27 1990-10-31 Parenta Srl Verfahren und vorrichtung zur darstellung von sterilen einspritzbaren antibiotikapulvern

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
JPS5446001U (de) * 1977-09-07 1979-03-30
FR2403080A1 (fr) * 1977-09-15 1979-04-13 Heyden Chem Fab Preparation de nitrofurantoine a effet retard pour administration orale et son procede de fabrication
DE2805106A1 (de) * 1978-02-07 1979-08-16 Hoechst Ag Mikrokapseln aus polyvinylalkohol mit fluessigem, wasserunloeslichem fuellgut und verfahren zu deren herstellung
JPS56156214A (en) * 1980-05-02 1981-12-02 Yoshiaki Kawashima Preparation of tableting enteric microcapsule
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
SE8404808L (sv) * 1983-10-03 1985-04-04 Avner Rotman Mikrokapslat lekemedel i sot matris
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPS61218516A (ja) * 1985-03-25 1986-09-29 Ichimaru Fuarukosu Kk 徐放性マイクロカプセルの製造法
DE69016788T2 (de) * 1990-11-29 1995-06-22 Faulding F H & Co Ltd Verfahren zur Herstellung von Flüssigkeiten enthaltenden Pulvern.
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112083A (de) * 1970-09-16 1972-03-20
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4011956A1 (de) * 1989-04-27 1990-10-31 Parenta Srl Verfahren und vorrichtung zur darstellung von sterilen einspritzbaren antibiotikapulvern
GB2231266A (en) * 1989-04-27 1990-11-14 Parenta Srl The preparation of sterile powders of antibiotics

Also Published As

Publication number Publication date
DK134424C (de) 1977-05-23
AT337902B (de) 1977-07-25
ES414908A1 (es) 1976-06-01
DK134423C (da) 1977-04-12
DE2325410A1 (de) 1973-11-29
FR2185390B1 (de) 1977-04-15
AR197900A1 (es) 1974-05-15
IL42312A0 (en) 1973-07-30
BE799783A (fr) 1973-11-19
IL42312A (en) 1977-01-31
IE37637B1 (en) 1977-09-14
DK134424B (da) 1976-11-08
AU475493B2 (en) 1976-08-26
ATA439473A (de) 1976-11-15
JPS49116220A (de) 1974-11-06
CA1025359A (en) 1978-01-31
JPS4954518A (de) 1974-05-27
DK134423B (da) 1976-11-08
NL7307033A (de) 1973-11-21
ZA733406B (en) 1975-03-26
AU5596573A (en) 1974-11-21
HU167559B (de) 1975-11-28
FR2185390A1 (de) 1974-01-04
IE37637L (en) 1973-11-19
DK190774A (da) 1975-10-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee