GB1397407A - Aluminium containing pharmaceutical compounds - Google Patents
Aluminium containing pharmaceutical compoundsInfo
- Publication number
- GB1397407A GB1397407A GB403572*[A GB403572A GB1397407A GB 1397407 A GB1397407 A GB 1397407A GB 403572 A GB403572 A GB 403572A GB 1397407 A GB1397407 A GB 1397407A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutically active
- aluminium
- active compound
- acid
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 229910052782 aluminium Inorganic materials 0.000 title abstract 4
- 239000004411 aluminium Substances 0.000 title abstract 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 abstract 2
- -1 aluminium alkoxy compound Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- OTJFTZJLQGKXCI-UHFFFAOYSA-N 2-acetyloxybenzoic acid;2-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1O.CC(=O)OC1=CC=CC=C1C(O)=O OTJFTZJLQGKXCI-UHFFFAOYSA-N 0.000 abstract 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 abstract 1
- HWGBHCRJGXAGEU-UHFFFAOYSA-N Methylthiouracil Chemical compound CC1=CC(=O)NC(=S)N1 HWGBHCRJGXAGEU-UHFFFAOYSA-N 0.000 abstract 1
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- 239000004146 Propane-1,2-diol Substances 0.000 abstract 1
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- SMZOGRDCAXLAAR-UHFFFAOYSA-N aluminium isopropoxide Chemical compound [Al+3].CC(C)[O-].CC(C)[O-].CC(C)[O-] SMZOGRDCAXLAAR-UHFFFAOYSA-N 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229960002061 ergocalciferol Drugs 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000001746 injection moulding Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960002545 methylthiouracil Drugs 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- 235000019366 oxytetracycline Nutrition 0.000 abstract 1
- DBABZHXKTCFAPX-UHFFFAOYSA-N probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 abstract 1
- 229960004063 propylene glycol Drugs 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 abstract 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 abstract 1
- 235000001892 vitamin D2 Nutrition 0.000 abstract 1
- 239000011653 vitamin D2 Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/06—Aluminium compounds
- C07F5/069—Aluminium compounds without C-aluminium linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB403572*[A GB1397407A (en) | 1971-07-06 | 1972-01-28 | Aluminium containing pharmaceutical compounds |
| DE2229027A DE2229027A1 (de) | 1971-07-06 | 1972-06-14 | Verfahren zur herstellung von arzneimittelzubereitungen |
| FR7222751A FR2144680B1 (cg-RX-API-DMAC10.html) | 1971-07-06 | 1972-06-23 | |
| US268266A US3880901A (en) | 1971-07-06 | 1972-07-03 | Aluminum-containing pharmaceutical compositions |
| CH999672A CH579919A5 (cg-RX-API-DMAC10.html) | 1971-07-06 | 1972-07-04 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3165871 | 1971-07-06 | ||
| GB403572*[A GB1397407A (en) | 1971-07-06 | 1972-01-28 | Aluminium containing pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1397407A true GB1397407A (en) | 1975-06-11 |
Family
ID=26238785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB403572*[A Expired GB1397407A (en) | 1971-07-06 | 1972-01-28 | Aluminium containing pharmaceutical compounds |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3880901A (cg-RX-API-DMAC10.html) |
| CH (1) | CH579919A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2229027A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2144680B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1397407A (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4229446A (en) * | 1979-03-13 | 1980-10-21 | Kyowa Hakko Kogyo Co., Ltd. | Aluminum acetylsalicylate glutaminate |
| ZA816685B (en) | 1980-10-03 | 1982-09-29 | Hoffmann La Roche | Aluminium compounds containing organic radicals |
| IT1150759B (it) * | 1982-04-05 | 1986-12-17 | Corvi Camillo Spa | Complessi organometallici di n-cicloesil-piperazino-acetammidi o propionammidi, loro preparazione e impiego come farmaci antiulcera-antisecretivi-tamponanti |
| FR2774906B1 (fr) * | 1998-02-13 | 2000-05-12 | Rhodia Chimie Sa | Systeme d'encapsulation a coeur organique et a ecorce minerale a base d'hydroxycarbonate d'aluminium et son procede de preparation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2959606A (en) * | 1956-09-18 | 1960-11-08 | Lewis Howe Company | Production of aluminum acetylsalicylate |
| GB888666A (en) * | 1959-04-13 | 1962-01-31 | Hardman & Holden Ltd | Improvements relating to organic aluminium compounds |
| GB959282A (en) * | 1959-08-19 | 1964-05-27 | Hardman & Holden Ltd | Improvements relating to organic aluminium compounds |
| GB961299A (en) * | 1960-05-02 | 1964-06-17 | Hardman & Holden Ltd | Improvements relating to organic aluminium compounds |
| US3100787A (en) * | 1960-05-10 | 1963-08-13 | Jr Ludwig Adolph Staib | Basic aluminum salts of acetylsalicylate acid and a non-toxic water soluble acid |
| US3352893A (en) * | 1963-02-13 | 1967-11-14 | Chatten Drug & Chem Co | Method of producing hydroxy aluminum disalicylate |
-
1972
- 1972-01-28 GB GB403572*[A patent/GB1397407A/en not_active Expired
- 1972-06-14 DE DE2229027A patent/DE2229027A1/de active Pending
- 1972-06-23 FR FR7222751A patent/FR2144680B1/fr not_active Expired
- 1972-07-03 US US268266A patent/US3880901A/en not_active Expired - Lifetime
- 1972-07-04 CH CH999672A patent/CH579919A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2144680A1 (cg-RX-API-DMAC10.html) | 1973-02-16 |
| FR2144680B1 (cg-RX-API-DMAC10.html) | 1977-08-05 |
| DE2229027A1 (de) | 1973-01-18 |
| US3880901A (en) | 1975-04-29 |
| CH579919A5 (cg-RX-API-DMAC10.html) | 1976-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| PLE | Entries relating assignments, transmissions, licences in the register of patents | ||
| SP | Amendment (slips) printed | ||
| PCNP | Patent ceased through non-payment of renewal fee |