GB1392313A - Fluorenone derivatives - Google Patents
Fluorenone derivativesInfo
- Publication number
- GB1392313A GB1392313A GB2420972A GB2420972A GB1392313A GB 1392313 A GB1392313 A GB 1392313A GB 2420972 A GB2420972 A GB 2420972A GB 2420972 A GB2420972 A GB 2420972A GB 1392313 A GB1392313 A GB 1392313A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- alkyl
- cycloalkyl
- phenyl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008376 fluorenones Chemical class 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 16
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- XURZAOMZYUODPH-UHFFFAOYSA-N [1-(tert-butylamino)-3-(9-oxofluoren-1-yl)oxypropan-2-yl] 2,2-dimethylpropanoate Chemical compound C(C)(C)(C)NCC(COC1=CC=CC=2C3=CC=CC=C3C(C1=2)=O)OC(C(C)(C)C)=O XURZAOMZYUODPH-UHFFFAOYSA-N 0.000 abstract 1
- SYKNUAWMBRIEKB-UHFFFAOYSA-N [Cl].[Br] Chemical group [Cl].[Br] SYKNUAWMBRIEKB-UHFFFAOYSA-N 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000006193 alkinyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 238000006264 debenzylation reaction Methods 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005504 styryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH768071 | 1971-05-26 | ||
| CH223772A CH558330A (de) | 1972-02-16 | 1972-02-16 | Verfahren zur herstellung neuer fluorenone. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1392313A true GB1392313A (en) | 1975-04-30 |
Family
ID=25689867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2420972A Expired GB1392313A (en) | 1971-05-26 | 1972-05-23 | Fluorenone derivatives |
Country Status (20)
| Country | Link |
|---|---|
| AT (1) | AT337168B (enExample) |
| AU (1) | AU474417B2 (enExample) |
| BE (1) | BE783888A (enExample) |
| CA (1) | CA979895A (enExample) |
| CS (1) | CS177083B2 (enExample) |
| DD (1) | DD99351A5 (enExample) |
| DE (1) | DE2224792A1 (enExample) |
| DK (1) | DK136310B (enExample) |
| ES (2) | ES403127A1 (enExample) |
| FR (1) | FR2139113B1 (enExample) |
| GB (1) | GB1392313A (enExample) |
| HU (1) | HU164320B (enExample) |
| IE (1) | IE38022B1 (enExample) |
| IL (1) | IL39516A (enExample) |
| NL (1) | NL7206792A (enExample) |
| NO (1) | NO135028C (enExample) |
| PL (1) | PL84602B1 (enExample) |
| RO (1) | RO64096A (enExample) |
| SE (1) | SE387332B (enExample) |
| SU (1) | SU549075A3 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004959A (en) * | 1996-05-30 | 1999-12-21 | Hoechst Marion Roussel, Inc. | Alkyloxyamino substituted fluorenones and their use as protein kinase-C inhibitors |
-
1972
- 1972-05-17 SE SE7206413A patent/SE387332B/xx unknown
- 1972-05-17 DK DK246472AA patent/DK136310B/da unknown
- 1972-05-18 NO NO1765/72A patent/NO135028C/no unknown
- 1972-05-19 NL NL7206792A patent/NL7206792A/xx not_active Application Discontinuation
- 1972-05-20 DE DE19722224792 patent/DE2224792A1/de active Pending
- 1972-05-23 GB GB2420972A patent/GB1392313A/en not_active Expired
- 1972-05-24 BE BE783888A patent/BE783888A/xx unknown
- 1972-05-24 SU SU1787935A patent/SU549075A3/ru active
- 1972-05-24 ES ES403127A patent/ES403127A1/es not_active Expired
- 1972-05-24 PL PL1972155568A patent/PL84602B1/pl unknown
- 1972-05-24 IE IE697/72A patent/IE38022B1/xx unknown
- 1972-05-24 DD DD163166A patent/DD99351A5/xx unknown
- 1972-05-24 RO RO7200071011A patent/RO64096A/ro unknown
- 1972-05-24 IL IL39516A patent/IL39516A/xx unknown
- 1972-05-24 HU HUSA2365A patent/HU164320B/hu unknown
- 1972-05-25 CA CA142,961A patent/CA979895A/en not_active Expired
- 1972-05-25 CS CS3597A patent/CS177083B2/cs unknown
- 1972-05-25 AU AU42771/72A patent/AU474417B2/en not_active Expired
- 1972-05-25 AT AT450972A patent/AT337168B/de not_active IP Right Cessation
- 1972-05-26 FR FR7218828A patent/FR2139113B1/fr not_active Expired
-
1974
- 1974-09-30 ES ES430540A patent/ES430540A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004959A (en) * | 1996-05-30 | 1999-12-21 | Hoechst Marion Roussel, Inc. | Alkyloxyamino substituted fluorenones and their use as protein kinase-C inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2139113A1 (enExample) | 1973-01-05 |
| SU549075A3 (ru) | 1977-02-28 |
| NO135028B (enExample) | 1976-10-18 |
| CA979895A (en) | 1975-12-16 |
| DK136310C (enExample) | 1978-02-20 |
| CS177083B2 (enExample) | 1977-07-29 |
| ES403127A1 (es) | 1975-12-16 |
| BE783888A (fr) | 1972-11-24 |
| ATA450972A (de) | 1976-10-15 |
| IE38022B1 (en) | 1977-12-07 |
| NO135028C (enExample) | 1977-01-26 |
| IE38022L (en) | 1972-11-26 |
| DD99351A5 (enExample) | 1973-08-05 |
| AU4277172A (en) | 1973-11-29 |
| PL84602B1 (en) | 1976-04-30 |
| SE387332B (sv) | 1976-09-06 |
| DK136310B (da) | 1977-09-26 |
| AU474417B2 (en) | 1976-07-22 |
| NL7206792A (enExample) | 1972-11-28 |
| HU164320B (enExample) | 1974-01-28 |
| ES430540A1 (es) | 1977-02-16 |
| DE2224792A1 (de) | 1972-12-07 |
| FR2139113B1 (enExample) | 1975-12-26 |
| IL39516A (en) | 1975-05-22 |
| RO64096A (fr) | 1978-08-15 |
| IL39516A0 (en) | 1972-07-26 |
| AT337168B (de) | 1977-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |