GB1390336A - Antibiotic b-41 - Google Patents

Antibiotic b-41

Info

Publication number
GB1390336A
GB1390336A GB2743773A GB2743773A GB1390336A GB 1390336 A GB1390336 A GB 1390336A GB 2743773 A GB2743773 A GB 2743773A GB 2743773 A GB2743773 A GB 2743773A GB 1390336 A GB1390336 A GB 1390336A
Authority
GB
United Kingdom
Prior art keywords
antibiotic
chlorophenyl
constituents
methylcarbamate
june
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2743773A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of GB1390336A publication Critical patent/GB1390336A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Biochemistry (AREA)
  • Dentistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB2743773A 1972-06-08 1973-06-08 Antibiotic b-41 Expired GB1390336A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP47057058A JPS4914624A (me) 1972-06-08 1972-06-08

Publications (1)

Publication Number Publication Date
GB1390336A true GB1390336A (en) 1975-04-09

Family

ID=13044830

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2743773A Expired GB1390336A (en) 1972-06-08 1973-06-08 Antibiotic b-41

Country Status (11)

Country Link
JP (1) JPS4914624A (me)
BR (1) BR7304308D0 (me)
CH (2) CH585514A5 (me)
DE (1) DE2329486C2 (me)
ES (1) ES415591A1 (me)
FR (1) FR2187778B1 (me)
GB (1) GB1390336A (me)
IL (1) IL42401A (me)
IT (1) IT986430B (me)
SU (2) SU588926A3 (me)
ZA (1) ZA733857B (me)

Cited By (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463773A1 (fr) * 1979-08-23 1981-02-27 Sankyo Co Compose ayant des activites acaricides et anthelmintiques obtenu par culture d'un micro-organisme du genre streptomyces
EP0059074A1 (en) * 1981-02-23 1982-09-01 Sankyo Company Limited Anthelmintic composition and the use thereof
US4898821A (en) * 1984-09-14 1990-02-06 American Cyanamid Company Antibiotic compounds and their preparation
US4980370A (en) * 1988-07-05 1990-12-25 Pfizer Inc. Antiparasitic agents
EP0410615A1 (en) * 1989-07-26 1991-01-30 Pfizer Limited Antiparasitic agent
US5055596A (en) * 1987-11-03 1991-10-08 Beecham Group P.L.C. Derivatives of avermectin and milbemycin
US5378617A (en) * 1986-03-12 1995-01-03 American Cyanamid Company Process for the production of macrolide compounds
US5510251A (en) * 1984-06-05 1996-04-23 American Cyanamid Company Agents and method of production thereof
US5556868A (en) * 1992-03-07 1996-09-17 Pfizer Inc Antiparasitic avermectin and milbemycin derivatives
US5573946A (en) * 1988-02-25 1996-11-12 Pfizer Inc. Biologically pure culture of Streptomyces hygroscopicus ATCC 53718 capable of producing antibiotic compounds
US5620874A (en) * 1986-07-24 1997-04-15 Pfizer Inc. Process for producing parasiticidal milbemycin derivatives by culturing streptomyces
US6063394A (en) * 1996-04-09 2000-05-16 Bayer Aktiengesellschaft Injection formulations of avermectins and milbemycins based on castor oil
WO2003024223A1 (en) 2001-09-17 2003-03-27 Eli Lilly And Company Pesticidal formulations
US6733767B2 (en) 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
US6797701B2 (en) 1998-11-19 2004-09-28 Pfizer Inc. Antiparasitic formulations
WO2005063015A1 (en) 2003-12-19 2005-07-14 Merial Limited Stabilized formulation of ivermerctin feed premix
WO2007024719A2 (en) 2005-08-19 2007-03-01 Merial Limited Long acting injectable parasiticidal formulations
WO2011051159A1 (en) 2009-10-28 2011-05-05 Consiglio Nazionale Delle Ricerche Avermectins and milbemycins for the treatment of flavivirus infections
WO2011069143A1 (en) 2009-12-04 2011-06-09 Merial Limited Pesticidal bis-organosulfur compounds
WO2011075591A1 (en) 2009-12-17 2011-06-23 Merial Limited Anti parasitic dihydroazole compounds and compositions comprising same
WO2011123773A1 (en) 2010-04-02 2011-10-06 Merial Limited Parasiticidal compositions comprising multiple active agents, methods and uses thereof
WO2012068202A1 (en) 2010-11-16 2012-05-24 Merial Limited Novel monensin derivatives for the treatment and prevention of protozoal infections
EP2465851A1 (en) 2006-07-05 2012-06-20 Aventis Agriculture 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
WO2013003505A1 (en) 2011-06-27 2013-01-03 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
EP2550962A2 (en) 2008-11-19 2013-01-30 Merial Limited Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
WO2013039948A1 (en) 2011-09-12 2013-03-21 Merial Limited Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
WO2013074892A1 (en) 2011-11-17 2013-05-23 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
WO2013119442A1 (en) 2012-02-06 2013-08-15 Merial Limited Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
WO2013126694A1 (en) 2012-02-23 2013-08-29 Merial Limited Topical compositions comprising fipronil and permethrin and methods of use
EP2639228A2 (en) 2007-05-15 2013-09-18 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
WO2013158894A1 (en) 2012-04-20 2013-10-24 Merial Limited Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
WO2014081697A2 (en) 2012-11-20 2014-05-30 Merial Limited Anthelmintic compounds and compositions and method of using thereof
WO2014121064A1 (en) 2013-01-31 2014-08-07 Merial Limited Method for treating and curing leishmaniosis using fexinindazole
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
EP2886640A1 (en) 2013-12-18 2015-06-24 Riga Technical University Process for isolation of milbemycins A3 and A4
WO2015161224A1 (en) 2014-04-17 2015-10-22 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
WO2015179414A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
WO2016069983A1 (en) 2014-10-31 2016-05-06 Merial, Inc. Parasiticidal composition comprising fipronil
WO2016138339A1 (en) 2015-02-26 2016-09-01 Merial, Inc. Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof
WO2016164487A1 (en) 2015-04-08 2016-10-13 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
WO2016191389A2 (en) 2015-05-27 2016-12-01 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
US9662309B2 (en) 2004-11-09 2017-05-30 Bayer Intellectual Property Gmbh Anti-demodicosis agent
WO2017147352A1 (en) 2016-02-24 2017-08-31 Merial, Inc. Antiparasitic isoxazoline compounds, long-acting injectable formulations comprising them, methods and uses thereof
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
WO2019005700A1 (en) 2017-06-26 2019-01-03 Merial, Inc. DOUBLE-ACTING PARASITICIDE GRANULATE COMPOSITIONS, METHODS AND USES THEREOF
WO2019036407A1 (en) 2017-08-14 2019-02-21 Merial, Inc. PYRAZOLE-ISOXAZOLINE COMPOUNDS WITH PESTICIDE AND PARASITICIDE ACTIVITY
EP3498696A1 (en) 2008-11-14 2019-06-19 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino parasiticidal compounds
WO2019152808A1 (en) 2018-02-01 2019-08-08 Yale University Compositions and methods for inhibition of nuclear-penetrating antibodies
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020150032A1 (en) 2019-01-16 2020-07-23 Boehringer Ingelheim Animal Health USA Inc. Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
WO2020180635A1 (en) 2019-03-01 2020-09-10 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
WO2020191091A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
WO2021013825A1 (en) 2019-07-22 2021-01-28 Intervet International B.V. Soft chewable veterinary dosage form
WO2021242581A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5858164B2 (ja) * 1975-09-06 1983-12-23 イシカワジマハリマジユウコウギヨウ カブシキガイシヤ ハツリソウチ
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
EP0102702B1 (en) * 1982-07-22 1987-07-29 Imperial Chemical Industries Plc Methods and compositions of combating pests
JPS60141293A (ja) * 1983-12-28 1985-07-26 Kitasato Inst:The 新規制癌性抗生物質８１−４８４およびその製造法
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5290804A (en) * 1991-05-01 1994-03-01 Merck & Co., Inc. Anthelmintic milbemycin analogs of novel microorganisms
JP2952265B2 (ja) * 1993-11-29 1999-09-20 井筒屋化学産業株式会社 松類の枯損防止用組成物及び防止方法
EP4337015A1 (en) 2021-05-14 2024-03-20 Syngenta Crop Protection AG Insect, acarina and nematode pest control
WO2023203038A1 (en) 2022-04-19 2023-10-26 Syngenta Crop Protection Ag Insect, acarina and nematode pest control

Cited By (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463773A1 (fr) * 1979-08-23 1981-02-27 Sankyo Co Compose ayant des activites acaricides et anthelmintiques obtenu par culture d'un micro-organisme du genre streptomyces
EP0059074A1 (en) * 1981-02-23 1982-09-01 Sankyo Company Limited Anthelmintic composition and the use thereof
US5510251A (en) * 1984-06-05 1996-04-23 American Cyanamid Company Agents and method of production thereof
US4898821A (en) * 1984-09-14 1990-02-06 American Cyanamid Company Antibiotic compounds and their preparation
US5378617A (en) * 1986-03-12 1995-01-03 American Cyanamid Company Process for the production of macrolide compounds
US5721271A (en) * 1986-07-24 1998-02-24 Pfizer Inc. Parasiticidal milbemycin derivatives
US5620874A (en) * 1986-07-24 1997-04-15 Pfizer Inc. Process for producing parasiticidal milbemycin derivatives by culturing streptomyces
US5055596A (en) * 1987-11-03 1991-10-08 Beecham Group P.L.C. Derivatives of avermectin and milbemycin
US5573946A (en) * 1988-02-25 1996-11-12 Pfizer Inc. Biologically pure culture of Streptomyces hygroscopicus ATCC 53718 capable of producing antibiotic compounds
US5112746A (en) * 1988-07-05 1992-05-12 Pfizer Inc. Method for making antiparasitic agents
US5057498A (en) * 1988-07-05 1991-10-15 Pfizer Inc. Antiparastic agents
US4980370A (en) * 1988-07-05 1990-12-25 Pfizer Inc. Antiparasitic agents
US5073567A (en) * 1989-07-26 1991-12-17 Pfizer Inc. Antiparasitic agent
EP0410615A1 (en) * 1989-07-26 1991-01-30 Pfizer Limited Antiparasitic agent
US5556868A (en) * 1992-03-07 1996-09-17 Pfizer Inc Antiparasitic avermectin and milbemycin derivatives
US6063394A (en) * 1996-04-09 2000-05-16 Bayer Aktiengesellschaft Injection formulations of avermectins and milbemycins based on castor oil
US6733767B2 (en) 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
BG65440B1 (bg) * 1998-11-19 2008-08-29 Pfizer Inc. Антипаразитни форми
US6797701B2 (en) 1998-11-19 2004-09-28 Pfizer Inc. Antiparasitic formulations
WO2003024223A1 (en) 2001-09-17 2003-03-27 Eli Lilly And Company Pesticidal formulations
EP3488698A1 (en) 2001-09-17 2019-05-29 Elanco US Inc. Pesticidal formulations
EP2347654A1 (en) 2001-09-17 2011-07-27 Eli Lilly and Company Pesticidal formulations
WO2005063015A1 (en) 2003-12-19 2005-07-14 Merial Limited Stabilized formulation of ivermerctin feed premix
US7671034B2 (en) 2003-12-19 2010-03-02 Merial Limited Stabilized formulation of ivermectin feed premix with an extended shelf life
US9662309B2 (en) 2004-11-09 2017-05-30 Bayer Intellectual Property Gmbh Anti-demodicosis agent
EP3479818A1 (en) 2005-08-19 2019-05-08 Merial, Inc. Long acting injectable parasiticidal formulations
WO2007024719A2 (en) 2005-08-19 2007-03-01 Merial Limited Long acting injectable parasiticidal formulations
EP2465851A1 (en) 2006-07-05 2012-06-20 Aventis Agriculture 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
EP3088384A1 (en) 2007-05-15 2016-11-02 Merial, Inc. Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
EP2639228A2 (en) 2007-05-15 2013-09-18 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
EP3498696A1 (en) 2008-11-14 2019-06-19 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino parasiticidal compounds
EP2550962A2 (en) 2008-11-19 2013-01-30 Merial Limited Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
EP2327410A1 (en) * 2009-10-28 2011-06-01 Consiglio Nazionale Delle Ricerche - Infm Istituto Nazionale Per La Fisica Della Materia Avermectins and milbemycins for the treatment of flavivirus infections
WO2011051159A1 (en) 2009-10-28 2011-05-05 Consiglio Nazionale Delle Ricerche Avermectins and milbemycins for the treatment of flavivirus infections
US8741856B2 (en) 2009-10-28 2014-06-03 Consiglio Nazionale Delle Ricerche Avermectins and milbemycins for the treatment, prevention or amelioration of flavivirus infections
WO2011069143A1 (en) 2009-12-04 2011-06-09 Merial Limited Pesticidal bis-organosulfur compounds
EP3560923A1 (en) 2009-12-17 2019-10-30 Boehringer Ingelheim Animal Health USA Inc. Anti parasitic dihydroazole compounds and compositions comprising same
EP3078664A1 (en) 2009-12-17 2016-10-12 Merial Inc. Antiparasitic dihydroazole compositions
WO2011075591A1 (en) 2009-12-17 2011-06-23 Merial Limited Anti parasitic dihydroazole compounds and compositions comprising same
WO2011123773A1 (en) 2010-04-02 2011-10-06 Merial Limited Parasiticidal compositions comprising multiple active agents, methods and uses thereof
WO2012068202A1 (en) 2010-11-16 2012-05-24 Merial Limited Novel monensin derivatives for the treatment and prevention of protozoal infections
WO2013003505A1 (en) 2011-06-27 2013-01-03 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
EP3172964A1 (en) 2011-09-12 2017-05-31 Merial Inc. Parasiticidal compositions comprising an isoxazoline active agent, method and uses thereof
WO2013039948A1 (en) 2011-09-12 2013-03-21 Merial Limited Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
EP3788874A1 (en) 2011-09-12 2021-03-10 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising an isoxazoline active agent, method and uses thereof
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
WO2013074892A1 (en) 2011-11-17 2013-05-23 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
EP3766491A1 (en) 2012-02-06 2021-01-20 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
EP3061454A1 (en) 2012-02-06 2016-08-31 Merial, Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
WO2013119442A1 (en) 2012-02-06 2013-08-15 Merial Limited Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
EP3659439A1 (en) 2012-02-23 2020-06-03 Boehringer Ingelheim Animal Health USA Inc. Topical compositions comprising fipronil and permethrin and methods of use
WO2013126694A1 (en) 2012-02-23 2013-08-29 Merial Limited Topical compositions comprising fipronil and permethrin and methods of use
EP3453702A2 (en) 2012-04-20 2019-03-13 Merial, Inc. Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
EP3763706A1 (en) 2012-04-20 2021-01-13 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
WO2013158894A1 (en) 2012-04-20 2013-10-24 Merial Limited Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
EP3428162A1 (en) 2012-11-20 2019-01-16 Merial Inc. Anthelmintic compounds and compositions and method of using thereof
WO2014081697A2 (en) 2012-11-20 2014-05-30 Merial Limited Anthelmintic compounds and compositions and method of using thereof
WO2014121064A1 (en) 2013-01-31 2014-08-07 Merial Limited Method for treating and curing leishmaniosis using fexinindazole
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
EP3733664A1 (en) 2013-11-01 2020-11-04 Boehringer Ingelheim Animal Health USA Inc. Antiparisitic and pesticidal isoxazoline compounds
EP2886640A1 (en) 2013-12-18 2015-06-24 Riga Technical University Process for isolation of milbemycins A3 and A4
WO2015161224A1 (en) 2014-04-17 2015-10-22 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
WO2015179414A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
EP3517524A1 (en) 2014-06-19 2019-07-31 Merial Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
WO2016069983A1 (en) 2014-10-31 2016-05-06 Merial, Inc. Parasiticidal composition comprising fipronil
WO2016138339A1 (en) 2015-02-26 2016-09-01 Merial, Inc. Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof
WO2016164487A1 (en) 2015-04-08 2016-10-13 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
EP3922639A1 (en) 2015-05-20 2021-12-15 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
WO2016191389A2 (en) 2015-05-27 2016-12-01 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
WO2017147352A1 (en) 2016-02-24 2017-08-31 Merial, Inc. Antiparasitic isoxazoline compounds, long-acting injectable formulations comprising them, methods and uses thereof
EP3763211A1 (en) 2016-02-24 2021-01-13 Boehringer Ingelheim Animal Health USA Inc. Antiparasitic isoxazoline compounds, long-acting injectable formulations comprising them, methods and uses thereof
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
WO2019005700A1 (en) 2017-06-26 2019-01-03 Merial, Inc. DOUBLE-ACTING PARASITICIDE GRANULATE COMPOSITIONS, METHODS AND USES THEREOF
WO2019036407A1 (en) 2017-08-14 2019-02-21 Merial, Inc. PYRAZOLE-ISOXAZOLINE COMPOUNDS WITH PESTICIDE AND PARASITICIDE ACTIVITY
WO2019152808A1 (en) 2018-02-01 2019-08-08 Yale University Compositions and methods for inhibition of nuclear-penetrating antibodies
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
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ES415591A1 (es) 1976-07-01
IT986430B (it) 1975-01-30
ZA733857B (en) 1975-04-30
DE2329486C2 (de) 1984-01-12
AU5663173A (en) 1974-12-12
FR2187778A1 (me) 1974-01-18
IL42401A0 (en) 1973-07-30
SU588926A3 (ru) 1978-01-15
CH585789A5 (me) 1977-03-15
JPS4914624A (me) 1974-02-08
FR2187778B1 (me) 1976-06-11
DE2329486A1 (de) 1973-12-20
IL42401A (en) 1976-02-29
BR7304308D0 (pt) 1974-08-29
SU1360574A3 (ru) 1987-12-15
CH585514A5 (me) 1977-03-15

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Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19930607