GB1388887A - N-substituted n-heterocyclic compounds - Google Patents

N-substituted n-heterocyclic compounds

Info

Publication number
GB1388887A
GB1388887A GB3468772A GB3468772A GB1388887A GB 1388887 A GB1388887 A GB 1388887A GB 3468772 A GB3468772 A GB 3468772A GB 3468772 A GB3468772 A GB 3468772A GB 1388887 A GB1388887 A GB 1388887A
Authority
GB
United Kingdom
Prior art keywords
compounds
july
heterocyclic
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3468772A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Badische Anilin and Sodafabrik AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE, Badische Anilin and Sodafabrik AG filed Critical BASF SE
Publication of GB1388887A publication Critical patent/GB1388887A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1388887 N - (2,3 - diphenylpropyl)heterocyclic amines BADISCHE ANILIN- & SODAFABRIK AG 25 July 1972 [26 July 1971] 34687/72 Heading C2C The invention comprises compounds of formula and their pharmacologically useful salts wherein X is O, NH or NMe; m and n are each 1-3, but m + n is at least 4; p is 0 or 1, but when p is 1, m+n=2; and the Ph and heterocyclic radicals may be further substituted. In examples, these compounds are prepared by reacting a corresponding PhCH 2 CHPhCHO with the heterocyclic amine acid, simultaneously or subsequently, a reducing agent; in the latter case an intermediate enamine is first formed. The compounds may be subjected to optical resolution. Therapeutic compositions for oral or parenteral administration comprise compounds of the above formula, which are stated to cause a prolonged increase in blood pressure, stimulate the C.N.S., and counteract tetrabenzazineinduced paralysis of the eyelid in mice.
GB3468772A 1971-07-26 1972-07-25 N-substituted n-heterocyclic compounds Expired GB1388887A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712137275 DE2137275A1 (en) 1971-07-26 1971-07-26 N- (2,3-DIPHENYL-PROPYL-1) -CYCLOIMINE

Publications (1)

Publication Number Publication Date
GB1388887A true GB1388887A (en) 1975-03-26

Family

ID=5814829

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3468772A Expired GB1388887A (en) 1971-07-26 1972-07-25 N-substituted n-heterocyclic compounds

Country Status (5)

Country Link
BE (1) BE786745A (en)
DE (1) DE2137275A1 (en)
FR (1) FR2147164B1 (en)
GB (1) GB1388887A (en)
NL (1) NL7209703A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2825961A1 (en) * 1978-06-14 1980-01-03 Basf Ag FUNGICIDE AMINE
IL89997A0 (en) * 1988-04-25 1989-12-15 Lilly Co Eli Propanamine derivatives

Also Published As

Publication number Publication date
FR2147164A1 (en) 1973-03-09
DE2137275A1 (en) 1973-02-08
BE786745A (en) 1973-01-26
FR2147164B1 (en) 1975-11-28
NL7209703A (en) 1973-01-30

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees